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Christian Forst, PhD
Contact Information
UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390
Biography
Dr. Christian Forst has been an Assistant Professor in the Department of Clinical Sciences since Feb. 2008. Previously, he was Technical Staff Member in the Bioscience Division at Los Alamos National Laboratory from 1999 to 2008. From 1997 to 1999, he served as research associate in bioinformatics at the Beckman Institute, University of Illinois at Urbana-Champaign. Previous to this position he functioned as group leader in theory of molecular evolutionary dynamics at the Institute of Molecular Biotechnology, Jena, Germany.
Dr. Forst is author of over 40 peer-reviewed scientific articles which cover a spectrum of research areas such as chaotic behavior in population dynamic problems, generic properties of genotype-phenotype relationships, evolutionary dynamics and phenotypic error thresholds, theory of molecular evolution, evolution in molecular host-pathogen systems, metabolic pathway phylogenies, comparative analysis of pathway relationships, molecular biology foundation of host-pathogen interactions, drug and stress response networks and network proteomics. Highlights in his scientific career include the identification and theoretical description of neutral networks in genotype-phenotype maps and of the phenotypic error threshold in molecular evolution, the phylogenetic analysis of metabolic pathways, as well as the identification of a novel host-defence pathway against influenza infections.
He served and is still serving as ad hoc reviewer for journals, such as Advances in Complex Systems, Bioinformatics, BioMed Central Bioinformatics/Systems Biology, BioSilico, Bulletin of Mathematical Biology, Cell Biochemistry and Biophysics, Expert Opinion on Drug Discovery, Gene, Genome Biology, Journal of Theoretical Biology, Molecular Biology and Evolution, Molecular Systems Biology, The New Scientist, and Virus Research. Dr. Forst is a member of the editorial board of the International Journal of Cancer Genomics and Proteomics. He also served as reviewer on review panels of the National Institute of Health, US Department of Energy and the National Science Foundation. Dr. Forst was also a member of the review panel of the Life Sciences:Information Technology Program (IT:LS) of the Industry-University Cooperative Research Program (IUCRP aka UC Discovery Grants), Univ. of California, from 2000 to 2007.
Dr. Forst received a distinguished performance scholarship from the University of Vienna, Austria, in 1990 and a dissertation award with Magna cum Laude in 1993. He holds a BS in Astronomy, an MS in Chemistry and a PhD in Theoretical Chemistry, all from the University of Vienna, Austria.
Education
| Graduate School | University of Vienna - Austria (1993) |
| Graduate School | University of Vienna - Austria, Chemistry (1990) |
| Undergraduate | University of Vienna - Austria (1989) |
Research Interests
Publications
Orvedahl A, Sumpter R, Xiao G, Ng A, Zou Z, Tang Y, Narimatsu M, Gilpin C, Sun Q, Roth M, Forst CV, Wrana JL, Zhang YE, Luby-Phelps K, Xavier RJ, Xie Y, Levine B, Nature, 2011 Dec; 480 (7375):113-7
Mata MA, Satterly N, Versteeg GA, Frantz D, Wei S, Williams N, Schmolke M, Peña-Llopis S, Brugarolas J, Forst CV, White MA, García-Sastre A, Roth MG, Fontoura BM, Nature chemical biology, 2011 Oct; 7 (10):712-9
Tatebe K, Zeytun A, Ribeiro RM, Hoffmann R, Harrod KS, Forst CV, BMC bioinformatics, 2010 ; 11:170
Forst C.V., Flamm C., Hofacker I.L., Stadler P.F. , Bioinformatics , 2006; (7):67
Sohaee N, Forst CV, Journal of bioinformatics and computational biology, 2010 Dec; 8 (6):929-43
Stadler PF, Prohaska SJ, Forst CV, Krakauer DC, Theory in biosciences = Theorie in den Biowissenschaften, 2009 Aug; 128 (3):165-70
Gebert J., Motameny S., Faigle U., Forst C.V., Schrader R. , J. Comp. Biol. , 2008; (15):185-194
Forst C.V., Cabusora L., Mawuenyega K.G., and Chen X , Adv. Complex Sys. , 2006; (9):299-314
Forst C.V. , Drug Discovery Today , 2006; (11):220-227
Cabusora L., Sutton E., Fulmer A., Forst C.V. , Bioinformatics , 2005; (21):2898-2905
Related Links
Books
Forst CV, Springer Verlag (New York Dordrecht Heidelberg London) 2009
Honors/Awards
UT Southwestern Graduate School of Biomedical Sciences (2011)
Los Alamos National Laboratory, New Mexico (2006)
German Science Foundation (1996)
Univ. of Vienna, Austria (1993)
Univ. of Vienna, Austria (1990)
Nobel Laureate Conference, Lindau/Bodensee, Germany (1989)