Dr. Lu’s research interest is to use magnetic resonance imaging (MRI) technologies to study physiology and metabolism of the human brain, and to use this information for understanding how the brain functions and how clinical diagnosis of brain disorders can be improved. In particular, the focus of his research program is the measurement of cerebral blood flow, cerebral blood volume, blood oxygenation level, and cerebral metabolic rate of oxygen using advanced MRI techniques.
RESEARCH INTERESTS
Functional magnetic resonance imaging (fMRI)
Perfusion MRI
Cerebrovascular physiology
Diffusion MRI
MR physics and pulse sequence design
RECENT PUBLICATIONS
Lu, H., and van Zijl, P.C., "Experimental Separation of Intra and Extravascular BOLD Effects using Multi-echo VASO and BOLD fMRI at 1.5T and 3.0T." Magnetic Resonance in Medicine, 53:808-816, April 2005
Lu, H., Nagae-Poetscher, L.M., Golay, X., Lin D., Pomper M.G., and van Zijl, P.C., "Routine Clinical Brain MRI Sequences for Use at 3.0 Tesla." Journal of Magnetic Resonance Imaging, 22:13-22, July 2005
Lu, H., Basso, G., Serences, J.T., Yantis, S., Golay, X., and van Zijl, P.C., "Retinotopic mapping in human visual cortex using Vascular-Space-Occupancy (VASO) dependent fMRI." NeuroReport, 16:1635-1640, October 2005
Lu, H., Law, M., Johnson, G., Ge, Y., van Zijl, P.C., and Helpern, J.A., "Novel Approach to Measure Absolute Cerebral Blood Volume using Vascular-Space-Occupancy (VASO) Dependent MRI." Magnetic Resonance in Medicine, 54:1403-1411, December 2005
SIGNIFICANT PUBLICATIONS
Lu, H., Golay, X., Pekar, J.J., and van Zijl, P.C., "Functional Magnetic Resonance Imaging Based on Changes in Vascular Space Occupancy." Magnetic Resonance in Medicine, 50:263-274, 2003
Lu, H., Golay, X., Pekar, J.J., and van Zijl, P.C., "Sustained post-stimulus elevation in cerebral oxygen utilization following vascular recovery." Journal of Cerebral Blood Flow and Metabolism, 24:764-770, 2004
Lu, H., Nagae-Poetscher, L.M., Golay, X., Lin D., Pomper M.G., and van Zijl, P.C., "Routine Clinical Brain MRI Sequences for Use at 3.0 Tesla." Journal of Magnetic Resonance Imaging, 22:13-22, 2005
Lu, H., Law, M., Johnson, G., Ge, Y., van Zijl, P.C., and Helpern, J.A., "Novel Approach to Measure Absolute Cerebral Blood Volume using Vascular-Space-Occupancy (VASO) Dependent MRI." Magnetic Resonance in Medicine, 54:1403-1411, 2005
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