I am intereseted in the basic science and clinical applications of large dose per fraction radiation delivery using image-guided and stereotactic techniques. I am involved in the testing of these types of novel therapies in patients with cancer in the brain, chest, abdomen and pelvis.
RESEARCH INTERESTS
Stereotactic Body Radiation Therapy
Hypofractionated Radiation Therapy
Radiation Response Modifiers
RECENT PUBLICATIONS
Schefter, TE, Kavanagh, BD, Timmerman, RD, Cardenes, HR, Baron, A, Gaspar, LE, ?, "A phase I trial of stereotactic body radiation therapy (SBRT) for liver metastases" Int J Radiat Oncol Biol Phys, 62(5):1371-1378, 2005
Timmerman RD, Kavanagh BD, Cho LC, Papiez L, Xing L, "Stereotactic body radiation therapy in multiple organ sites" J Clin Oncol, 25(8):947-52, 2007
Park C, Papiez L, Zhang S, Story M, Timmerman RD, "Universal survival curve and single fraction equivalent dose: useful tools in understanding potency of ablative radiotherapy" Int J Radiat Oncol Biol Phys, 70(3):847-52, 2008
Heinzerling JH, Anderson JF, Papiez L, Boike T, Chien S, Zhang G, Abdulrahman R, Timmerman R, "Four-dimensional computed tomography scan analysis of tumor and organ motion at varying levels of abdominal compression during stereotactic treatment of lung and liver" Int J Radiat Oncol Biol Phys, 70(5):1571-8, 2008
Timmerman, RD, Bizekis, CS, Pass HI, Fong, Y, Dupuy, DE, Dawson, LA, and Lu, D, "Local Surgical, Ablative, and Radiation Treatment of Metastases" CA - A Journal for Clinicians, 59(3) May 2009
SIGNIFICANT PUBLICATIONS
Timmerman, R., Papiez, L., McGarry, R, Likes, L., DesRosiers, C., Bank, M., Frost, S., Randall, M., Williams, M., "Extracranial Stereotactic Radioablation: results of a phase I study in medically inoperable stage I non-small cell lung cancer" Chest, 124(5):1946-1955, 2003
Potters, L, Steinberg, M, Rose, C, Timmerman, R, Ryu, S, Hevezi, JM, Welsh, J, Mehta, M, Larson, DA, Janjan, NA, "American Society for Therapeutic Radiology and Oncology and American College of Radiology practice guidelines for the performance of stereotactic body radiation therapy" Int J Radiat Oncol Biol Phys, 60(4):1026-1032, 2004
Timmerman, R, McGarry, R, Yiannoutsos, C, Papiez, L, Tudor, K, DeLuca, J, Ewing, M, Abdulrahman, R, DeRosiers, C, Williams, M, Fletcher, J, "Excessive toxicity when treating central tumors in a phase II study of stereotactic body radiation therapy for medically inoperable early-stage lung cancer" J Clin Oncol, 24:4833-4839, 2006
Timmerman, RD, "An overview of hypofractionation and introduction to this issue of seminars in radiation oncology" Semin Radiat Oncol, 18(4):215-22, October 2008
Kavanagh, B., Timmerman, R.D., editors, "BOOK: Stereotactic Body Radiation Therapy" Publishers: Lippincott, Williams, and Wilkins, Baltimore, MD, 2005
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