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Amyn Habib

 
 
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Amyn Habib, M.D.

 Details of Research

Biographical Sketch Details of Research Personal Overview How to Contact
Amyn Habib
Name:
  Amyn A. Habib, M.D.
Academic Title:
  Assistant Professor
Primary Appointment:
  Neurology
School:
  Southwestern Medical School
Department Website:
  Department of Neurology: Chairman's Welcome
Lab Website:
  Habib Lab

 RESEARCH INTERESTS
 
Growth factor signaling in cancer
The role of inflammation in gliomagenesis
 
 RECENT PUBLICATIONS
 
Ramnarain DB, Park S, Lee DY, Hatanpaa KJ, Scoggin SO, Otu H, Libermann TA, Raisanen JM, Ashfaq R, Wong ET, Wu J, Elliott R, and Habib AA, "Differential gene expression analysis reveals generation of an autocrine loop by a mutant epidermal growth factor receptor in glioma cells" Cancer Res., 66 (2):867-874, 2006
DB Ramnarain, R Paulmurugan, S Park, BE Mickey, A Asaithamby, D Saha, MA Kelliher, P Mukhopadhyay, F Banani, CJ Madden, PS Wright, S Chakravarty, and AA Habib, "RIP1 links inflammatory and growth factor signaling pathways by regulating expression of the EGFR" Cell Death and Differentiation, 15:344-353, 2008
S Park, DB Ramnarain, KJ Hatanpaa, BE Mickey, D Saha, R Paulmurugan, CJ Madden, PS Wright, S Bhai, MA Ali, K Puttaparthi, W Hu, JL Elliott, O Stuve, and AA Habib, "The death domain containing kinase RIP1 regulates p27Kip 1 levels via a PI3K-Akt-Forkhead pathway" EMBO Reports, 9:766-73, August 2008
Park S, Hatanpaa KJ, Xie Y, Mickey BE, Madden CJ, Raisanen J, Ramnarain DB, Xiao G, Saha D, Boothman DA, Zhao D, Bachoo RM, Pieper RO, and Habib AA, "The receptor interacting protein inhibits p53 induction through NF-kappaB activation and confers a worse prognosis in glioblastoma" Cancer Research, 69:2809-2816, April 2009
Park S, Zhao D, Hatanpaa KJ, Mickey BE, Saha D, Boothman DA, Story MD, Wong ET, Burma S, Georgescu MM, Rangnekar VM, Chauncey SS, and Habib AA, "RIP1 activates PI3K-Akt via a dual mechanism involving NF-kappaB mediated inhibition of the mTOR-S6K-IRS1 negative feedback loop and downregulation of PTEN" Cancer Research, 69:4107-4111, 2009
 
 SIGNIFICANT PUBLICATIONS
 
Hognason T., Chatterjee S., Vartanian T., Ratan R. R., Ernewein K. M., and Habib A. A., "Epidermal growth factor receptor induced apoptosis: potentiation by inhibition of Ras signaling." FEBS Letters, 491:9-15, 2001
 
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