My primary interest is in developing Magnetic Resonance Imaging (MRI) tools for imaging novel agents to probe the tumor microenvironment, eg. 19F and ¹H based LacZ gene-reporter molecules, ¹H pO2 reporter molecules, macromolecular PARACEST contrast agents and nanoprobes. I am also interested in using MRI and MRS to investigate early changes following the onset of disease.
RECENT PUBLICATIONS
Jennewein M, Lewis MA, Zhao D, Tsyganov E, Slavine N, He J, Watkins L, Kodibagkar VD, O’Kelly S, Kulkarni P, Antich PP, Hermanne A, Rosch F, Mason RP, Thorpe PE, "Vascular Imaging of Solid Tumors in Rats with a Radioactive Arsenic-Labeled Antibody that Binds Exposed Phosphatidylserine" Clin Cancer Res, 14(5):1377-85, March 2008
Yu J, Kodibagkar VD*, Liu L, Mason RP, "A 19F-NMR approach using reporter molecule pairs to assess beta-galactosidase in human xenograft tumors in vivo" NMR Biomed, 21(7):704-712, February 2008
Liu L, Kodibagkar VD, Yu JX, Mason RP., "19F-NMR detection of lacZ gene expression via the enzymic hydrolysis of 2-fluoro-4-nitrophenyl {beta}-D-galactopyranoside in vivo in PC3 prostate tumor xenografts in the mouse." FASEB J, 2007
Kodibagkar VD, Yu J, Liu L, Hetherington HP, Mason RP., "Imaging beta-galactosidase activity using 19F chemical shift imaging of LacZ gene-reporter molecule 2-fluoro-4-nitrophenol-beta-D-galactopyranoside." Magn Reson Imaging., 24(7):959-962, September 2006
Kodibagkar VD, Cui W, Merritt ME, Mason RP., "Novel 1H NMR approach to quantitative tissue oximetry using hexamethyldisiloxane." Magn Reson Med., 55(4):743-748, April 2006
SIGNIFICANT PUBLICATIONS
Kodibagkar VD, Wang X, Pacheco-Torres J, Gulaka P, Mason RP, "Proton Imaging of Siloxanes to map Tissue Oxygenation Levels (PISTOL): a tool for quantitative tissue oximetry" NMR Biomed., 21(8):899-907, June 2008
Kodibagkar VD, Wang X, Mason RP, "Physical principles of quantitative nuclear magnetic resonance oximetry" Front Biosci, 13:1371-84, January 2008
Zhou Y, Gulaka P, Zhou J, Xiao M, Xu D, Hsieh JT, Kodibagkar VD, Sun X, "Preparation and Evaluation of a Radioisotope-incorporated Iron Oxide Core/Au Shell Nanoplatform for Dual Modality Imaging" J Biomed Nanotech, 4(4):474-481, January 2008
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