My primary interest is in developing Magnetic Resonance Imaging (MRI)tools for imaging novel agents to probe the tumor microenvironment, eg. 19F and 1H based LacZ gene-reporter molecules, 1H pO2 reporter molecule HMDSO, macromolecular PARACEST contrast agents. I am also interested in using MRI and MRS to investigate early changes following the onset of disease.
RECENT PUBLICATIONS
Liu L, Kodibagkar VD, Yu JX, Mason RP., "19F-NMR detection of lacZ gene expression via the enzymic hydrolysis of 2-fluoro-4-nitrophenyl {beta}-D-galactopyranoside in vivo in PC3 prostate tumor xenografts in the mouse." FASEB J, 2007
Kodibagkar VD, Yu J, Liu L, Hetherington HP, Mason RP., "Imaging beta-galactosidase activity using 19F chemical shift imaging of LacZ gene-reporter molecule 2-fluoro-4-nitrophenol-beta-D-galactopyranoside." Magn Reson Imaging., 24(7):959-962, September 2006
Kodibagkar VD, Cui W, Merritt ME, Mason RP., "Novel 1H NMR approach to quantitative tissue oximetry using hexamethyldisiloxane." Magn Reson Med., 55(4):743-748, April 2006
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