During recent years there has been an increased awareness of the need for adequate sedation and analgesia of critically ill pediatric patients. The choices of the treatment of pain are numerous, but in the Pediatric Intensive Care Unit (PICU) parenteral opioids are most commonly used. At equipotent doses, all mu agonist opioids (morphine, fentanyl, meperidine and codeine) produce similar physiologic effects and side effects. One of the most problematic side effects is opioid tolerance and withdrawal. My research centers on finding ways to manage pain control and sedation while avoiding the side effects of long term opioid use.
RESEARCH INTERESTS
Sedation
Pain control
Sedation
Sedation
RECENT PUBLICATIONS
Darnell, C, Thompson, J, Stromberg, D, Roy, L, Sheeran, P, "The Effect of Low Dose Naloxone Infusion on Fentanyl Requirements in Critically Ill Children" Pediatrics, 121/5:e1363-1371, May 2008
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