1. ADAMTS13 deficiency in TTP with or without HIV. 2. A controlled Study of TTP: Incidence Rates and Risk Factors. 3. Determination of the optimal platelet function test to detect aspirin and clopidogrel resistance in patients with stroke and coronary artery disease. 4. Defining hyperactive platelet syndrome in patients with thrombophilia.
RESEARCH INTERESTS
Thrombotic Thrombocytopenic Purpura
Platelet dysfunction
Hypercoagulability
Hemostasis
RECENT PUBLICATIONS
E Haley, N Babar, C Ritter, KA Downes, D Green, S Shurin, R Sarode, "The effect of ABO blood group on the collagen-binding assay for von Willebrand factor" Am J Hematol, 71:229-231, 2002
R Quinton, A Dyszkiewicz-Korpanty, J Yassine, R Sarode., "The Effects of a Pneumatic Tube Transport System on PFA-100? Closure Time and Whole Blood Platelet Aggregation." J Thromb Haemost, 2:354-356, 2004
KA Downes, R Yomtovian, HM Tsai, B Silver, C Rutherford, R Sarode, "Relapsed Thrombotic Thrombocytopenic Purpura Masquerading as an Acute Cerebrovascular Accident." J Clin Apheresis, In Press 2004
SIGNIFICANT PUBLICATIONS
GG Levy, WC Nichols, EC Lian, T Foroud, J McClintick, B McGee, A Yang , D Siemieniak, KR Stark, R Gruppo, R. Sarode, S Shurin, V Chandrasekaran, S Stabler, H Sabio, E Bouhassira, J Upshaw, D Ginsburg, HM Tsai., "Mutations in a Novel Member of the ADAMTS Gene Family Cause Thrombotic Thrombocytopenic Purpura." Nature, 413:488-494, 2001
HM Tsai, R Sarode, KA Downes, "Ultra Large Von Willebrand Factor Multimers and Normal ADAMTS13 Activity in the Umbilical Cord Blood" Thromb Res, 108:121-125, 2003
R Yomtovian, W Niklinski, B Silver, R Sarode, HM Tsai., "Rituximab for Thrombotic Thrombocytopenic Purpura. Report of A Case And Review of The Literature." Br J Haematol, 124:787-795, 2004
J Saavedra-Lozano, Y Cao, J Callison R Sarode, J Edgar, J Hatfield, L Picker, D. Peterson, O Ramilo, ES Vitetta, "An anti-CD45RO Immunotoxin Kills HIV-latently Infected Cells from Individuals on HAART with Little Effect of CD8 Memory" PNAS, USA, 101:2494-2499, 2004
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