NMR-based ligand screening of important biological target proteins
RECENT PUBLICATIONS
A.D. Ferguson, C.A. Amezcua, N.M. Halabi,. Y. Chelliah, M.K. Rosen, R. Ranganathan, J. Deisenhofer, "Signal transduction of TonB-dependent transporters" PNAS, 104:513-518, January 2007
A.D. Ferguson, V.M. Labunskyy, D.E. Fomenko, D. Arac, Y. Chelliah, C.A. Amezcua, J. Rizo, V.N. Gladyshev, and J. Deisenhofer, "NMR Structures of the Selenoproteins Sep15 and SelM Reveal Redox Activity of a New Thioredoxin-Like Family" JBC, 281:3536-3543, 2006
J.L. Best, C.A. Amezcua, B. Mayr, L. Flechner, C.M. Murawsky, B. Emerson, T. Zor, K.H. Gardner, and M. Montminy, "Identification of small-molecule antagonists that inhibit an activator:coactivator interaction" PNAS, 101:17623-17627, 2004
C.A. Amezcua, S.M. Harper, J. Rutter and K. Gardner, "Structure and Interactions of PAS kinase N-terminal PAS domain: Model for intramolecular kinase regulation" Structure, 10:1349-1361, 2002
J. Li, A.W.G. Burgett, L. Esser, C. Amezcua and P.G. Harran, "Total Synthesis of Nominal Diazonamides-Part2: On the true Structure and Origin of Natural Isolates" Angew. Chem. Int. Ed., 40(24):4770-4773, 2001
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