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Masashi Yanagisawa

 
 
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Masashi Yanagisawa, M.D., Ph.D.

 Details of Research

Biographical Sketch Details of Research Personal Overview How to Contact
Masashi Yanagisawa
Name:
  Masashi Yanagisawa, M.D., Ph.D.
Endowed Title:
  The Patrick E. Haggerty Distinguished Chair in Basic Biomedical Science
Academic Title:
  Professor
Primary Appointment:
  Biophysics and Molecular Genetics
School:
  Graduate School of Biomedical Sciences
Southwestern Medical School
Degree Program:
  Integrative Biology
Neuroscience
Affiliations:
  Howard Hughes Medical Institute
Department Website:
  Molecular Genetics Department
Lab Website:
  Masashi Yanagisawa Lab
Email:
  Masashi Yanagisawa, M.D., Ph.D.

 RESEARCH INTERESTS
 
Molecular genetics of sleep/wake regulation
Orphan GPCRs and their neuropeptide ligands
 
 RECENT PUBLICATIONS
 
Funato H, Tsai AL, Willie JT, Kisanuki Y, Williams SC, Sakurai T, Yanagisawa M., "Enhanced orexin receptor-2 signaling prevents diet-induced obesity and improves leptin sensitivity." Cell Metab., 9:64-76, January 2009
Barton M, Yanagisawa M., "Endothelin: 20 years from discovery to therapy." Can J. Physiol. Pharmacol., 86:485-98, 2008
Kelz MB, Sun Y, Chen J, Cheng Meng Q, Moore JT, Veasey SC, Dixon S, Thornton M, Funato H, Yanagisawa M., "An essential role for orexins in emergence from general anesthesia." Proc. Natl. Acad. Sci. USA, 105:1309-14, 2008
Mieda M, Williams SC, Richardson JA, Tanaka K, Yanagisawa M., "The dorsomedial hypothalamic nucleus as a putative food-entrainable circadian pacemaker." Proc. Natl. Acad. Sci. USA, 103:12150-5, 2006
Yamada T, Ohtani S, Sakurai T, Tsuji T, Kunieda T, Yanagisawa M., "Reduced expression of the endothelin receptor type B gene in piebald mice caused by insertion of a retroposon-like element in intron 1." J. Biol. Chem., 281:10799-807, 2006
 
 SIGNIFICANT PUBLICATIONS
 
Erik G. Puffenberger, Kiminori Hosoda, Sarah S. Washington, Kazuwa Nakao, Damiane deWit, Masashi Yanagisawa, Aravinda Chakravarti, "A missense mutation of the endothelin-B receptor gene in multigenic Hirschsprung’s disease" Cell, 79:1257-66, 1994
Kiminori Hosoda, Robert E. Hammer, James A. Richardson, Amy Greenstein Baynash, Jason C. Cheung, Adel Giaid, Masashi Yanagisawa, "Targeted and natural (piebald-lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice" Cell, 79:1267-76, 1994
Hiromasa Funato, Allen L. Tsai, Jon T. Willie, Yasushi Kisanuki, S. Clay Williams, Takeshi Sakurai, Masashi Yanagisawa, "Enhanced Orexin Receptor-2 Signaling Prevents Diet-Induced Obesity and Improves Leptin Sensitivity" Cell Metab., 9:64-76, 2009
 
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