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Susanne Mumby

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Susanne Mumby, Ph.D.

Details of Research

Name:		Susanne Mclain Mumby, Ph.D.
Academic Title:		Associate Professor
Primary Appointment:		Pharmacology
Secondary Appointment:		Graduate School of Biomedical Sciences Administration
School:		Graduate School of Biomedical Sciences Southwestern Medical School
Department Website:		Pharmacology
Email:		Susanne Mumby, Ph.D.

RESEARCH INTERESTS

	G Protein-Mediated Cell Signaling
	Structure and Function of Lipid Modificiations of Proteins

RECENT PUBLICATIONS

	Wyckoff, M.H., Chambliss, K.L., Mineo, C., Yahanna, I.S., Mendelsohn, M.E., Mumby, S.M., and Shaul, P.W., "Plasma membrane estrogen receptors are coupled to eNOS through G alpha i" J. Biol. Chem, 276:27071-27076, 2001
	Mumby, S.M., "Subcellular Localization of G Protein Subunits" Meth. Enzyol., 344:383-403, 2002
	Krumins, A.M. Barker, S.A., Huang, C., Sunahara, R.K., Yu, K., Wilkie, T.M., Gold, S.J., Mumby, S.M., "Differentially Regulated Expression of Endogenous RGS4 and RGS7." J. Biol. Chem., 279:2593-2599, 2004
	Mumby, S.M., "Gs Family of Heterotrimeric G. Proteins" Encyclopedia of Biological Chemistry, Vol. 2:337-342, 2004
	Han H, Fulin B, Sorrells L, Levitz R, Sinkovits R, and Mumby S, "Introduction to the AfCS Antibody Database: Tabulation of Our Experience with Commercially Available Antibodies" AfCS Research Reports, 1(7):doi:10.1038/afcs.da0 2003

SIGNIFICANT PUBLICATIONS

	Huang, C., Duncan, J.A., Gilman, A.G., and Mumby, S.M., "Persistent membrane association of activated and depalmitoylated G protein alpha subunits" Proc. Nat'l. Acad. Sci. USA, 96:412-417, 1999
	Mumby, S.M., Casey, P.J., Gilman, A.G., Gutowski, S., and Sternweis, P.C., "G protein gamma subunits contain a twenty-carbon isoprenoid" Proc. Nat'l. Acad. Sci. USA, 87:5873-5877, 1990
	Linder, M.E., Middleton, P., Hepler, J.R., Taussig, R., Gilman, A.G., and Mumby, S.M., "Lipid modifications of G proteins: alpha subunits are palmitoylated" Proc. Nat'l. Acad. Sci. USA, 90:3675-3679, 1993
	Huang, C., Hepler, J.R., Gilman, A.G., and Mumby, S.M., "Attenuation of Gi-andGq-mediated signaling by expression of RGS4 or GAIP in mammalian cells" Proc. Nat'l. Acad. Sci. USA, 94:6159-6163, 1997
	Huang, C., Hepler, J.R., Chen, L.T., Gilman, A.G., Anderson, R.G.W., and Mumby, S.M., "Organization of G proteins and adenylyl cyclase at the plasma membrane" Mol. Bio. Cell, 8:2365-2378, 1997

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