Kathryne and Gene Bishop Distinguished Chair in Pediatric Care at Children's Medical Center Associates First Capital Corporation Distinguished Chair in Pediatrics
Thomas, JA, Haudek, SB, Koroglu, T, Tsen, MF, Bryant, DD, White, DJ, Kusewitt, DF, Horton, J, and Giroir, B, "IRAK1 deletion disrupts cardiac Toll/IL-1 signaling in acute cardiac contractile dysfunction and lethal heart failure" Am J Physiol Heart Care Physiol, 285:H597-H606, 2003
White J, Carlson D, Thompson M, Maass DL, Sanders B, Giroir B, Horton JW, "Molecular and pharmacologic approaches to inhibiting nitric oxide after burn trauma" Am J Physiol Heart Care Physiol, 285:H1616-H1625, 2003
Garner LB, Willis MS, Carlson DL, DiMiao JM, White MD, Adams, GA, White DJ, Giroir BP, "Macrophage migration inhibitory factor (MIF) is a cardiac derived myocardial depressant factor" Am J Physiol Heart Care Physiol, 285:H2500-H0209, 2003
Barton P, Kalil A, Levin M, Goldstein B, Jefferson L, Brilli R, Takano J, Martin L, Quint P, Yeh T, Dalton H, Gessouron RM, Brown KE, Betts H, Macias W, Small DS, Wyss VL, Bates BM, Utterback BG, Giroir B, "Safety, Pharmacokinetics and pharmacodynamics of drotrecogin alfa (activated) in children with severe sepsis" Pediatrics, 113:7-17, January 2004
Graciano AL, Balko J, Rahn D, Giroir B, "The pediatric multiple organ dysfunction score (P-MODS): Development and validation of an objective scale to measure the severity of multiple organ dysfunction in critically ill children" Critical Care Medicine, 33(7):1484-1491, 2005
SIGNIFICANT PUBLICATIONS
Bryant, D, Becker, L, Richardson, J, Shelton, J, Franco, F, Peshock, R, and Giroir, B, "Cardiac failure in transgenic mice with myocardial expression of tumor necrosis factor-(alpha) (TNF)" Circulation, 97:1375-1381
Levin, M, Quint, PA, Goldstein, B, Barton, P, Bradley, JS, Shemie, SD, Yeh, T, Kim, SS, Cafaro, DP, Scannon, P, Giroir, B, "Recombinant bactericidal/permeability-increasing protein (rBPI21) as adjunctive treatment for children with severe meningococcal sepsis: a randomized trial" Lancet, 356:961-67, 2000
Braciano, AL, Bryant, DD, White, DJ, Horton, J, Bowles, NE and Giroir, B, "Targeted disruption of ICAM-1, P-selection genes improves cardiac function and survival in TNF-(alpha) transgenic mice" Am J Phys, Heart Circ Physiol, 280:H1464-71, 2001
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