Development of novel chemotherapy regimens for children with recurrent cancer
Evaluation of quality of life and late effects of childhood cancer survivors
New therapies for childhood brain tumors
RECENT PUBLICATIONS
Chi SN, Zimmerman MA, Yao X, Fletcher W, Cohen K, Burger P, Biegel J, Rorke-Adams LF, Fisher M, Janss A, Mazewski C, Goldman S, Manley P, Bowers DC, Bendel A, Rubin J, Turner CD, Marcus K, Goumnerova L, Roberts C, Ullrich N, Chordas C, Kieran MW, "A single-arm, open label multi-institutional phase II study of multi-agent intrathecal and systemic chemotherapy with radiation therapy for children with newly-diagnosed central nervous system atypical teratoid/rhabdoid tumor" Journal of Clinical Oncology, 27:385-389, 2009
Hudson MM, Mulrooney DA, Bowers DC, Sklar CA, Green DM, Donaldson SS, Oeffinger KC, Neglia JP, Meadows AT, Robison LL, "High-risk populations identified in Childhood Cancer Survivor Study investigations: implications for risk-based surveillance." Journal of Clinical Oncology, 27:2405-2414, 2009
El-Khashab MA, Gargan L, Margraf L, Koral K, Nejat F, Weprin B, Swift D. Bowers, DC, "Predictors of tumor progression among children with gangliogliomas" Journal of Neurosurgery - Pediatrics, 3:461-466, 2009
Bowers DC, Gargan L, Weprin BE, Mulne AF, Elterman RD, Munoz L, Giller CA, Winick NJ, "The impact of site of tumor recurrence upon survival for children with recurrent or progressive medulloblastoma" Journal of Neurosurgery - Pediatrics, 107:5-10, 2007
SIGNIFICANT PUBLICATIONS
Bowers DC, Fan S, Willimas JA, Rosen EM, Laterra J, "Hepatocyte growth factor activates the Akt pathway and inhibits chemotherapy and radiation induced cell death in human glioma cells" Cancer Research, 60 (15):4277-4283, 2000
Bowers DC. McNeil DE. Liu Y. Yasui Y. Stovall M. Gurney JG. Hudson MM. Donaldson SS. Packer RJ. Mitby PA. Kasper CE. Robison LL. Oeffinger KC., "Stroke as a late treatment effect of Hodgkin’s disease: a report from the Childhood Cancer Survivor Study" Journal of Clinical Oncology, 23:6508-6515, 2005
Bowers DC, Aquino VM, Leavey PJ, Bash RO, Journeycake JM, Tomlinson G, Mulne AF, Haynes HJ, Winick NJ, "Phase I study of oral cyclophosphamides and oral topotecan for children with recurrent or refractory solid tumors" Pediatric Blood and Cancer, 42:93-98, 2004
Bowers DC, Gargan L, Kapur P, Reisch JS, Mulne AF, Shapiro KN, Elterman RD, Winick NJ, Margraf LR, "Study of the MIB-1 labeling index as a predictor of tumor progression in pilocytic astrocytomas in children and adolescents" Journal of Clinical Oncology, 21:2963 - 2973, 2006
Bowers DC, Liu Y, Leisenring W, McNeil E, Stovall M, Gurney JG, Robison LL, Packer RJ, Oeffinger KC., "Late-occurring stroke among long-term survivors of childhood leukemia and brain tumors: a report from the Childhood Cancer Survivor Study." Journal of Clinical Oncology, 24:5277-5282, 2005
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