Development of stem cell transplant protocols for children with malignant and non-malignant disorders.
Development of treatment strategies to manage the complications of stem cell transplant and chemotherapy.
Management of bacterial and fungal infections in children with malignancies.
Outpatient management of febrile neutropenia in selected patients with cancer.
Phase I and II trials of new chemotherapeutic agents in children with cancer.
RECENT PUBLICATIONS
Bowers DC, Aquino VM, Leavey PJ, Bash RO, Journeycake JM, Tomlinson G, Mulne AF, and Winick NJ, "Phase I study of oral cyclophosphamide and oral topotecan for children with recurrent and refractory solid tumors." Pediatr Blood Cancer, 42:93-98, 2004
Aquino VM, Weitman SD, Winick NJ, Blaney S, Furman WL, Kepner JL, Krailo M, Qu W, Bernstein M, "Phase I study of tirapazamine and cyclophosphamide in childrenwith refractor solid tumors." J Clin Oncol, 22:1413-1419, 2004
Aquino VM, Weitman SD, Winick NJ, Blaney S, Furman WL, Kepner JL, Krailo M, Qu W, Bernstein M, "Phase I study of tirapazamine and cyclophosphamide in children with refractory solid tumors." J Clin Oncol, 22:1413-1419, 2004
Aquino VM, Harvey A, Garvin JH, Godder K, Nieder ML, Adams RH, Jackson GB, Sandler ES for the Pediatric Blood and Marrow Transplant Corsortium, "The use of supplemental glutamine to decrease morbidity in children undergoing stem cell transplantation: A Pediatric Blood and Marrow Transplant Consortium Study." Bone Marrow Transplant, 36:611-616, 2005
SIGNIFICANT PUBLICATIONS
Aquino VM, Fort D, Kamen B, "A phase II study of carboplatin in the treatment of low grade optic gliomas." Journal of Neuro-Oncology, 41:255-259, 1999
Aquino VM, Herrera L, Sandler ES, Buchanan GR, "Oral ciprofloxacin in the outpatient management of children with cancer with febril neutropenia at low risk of bacteremia." Cancer 2000, 88:1710-1714
Aquino VM, Herrera L, Sandler ES, Buchanan GR, "Oral ciprofloxacin in the outpatient management of children with cancer with febril neutropenia at low risk of bacteremia." Cancer, 88:1710-1714, 2000
Baorto EP,Aquino VM, Mullen CA, Buchanan GR, "Clinical parameters associated with low bacteremia risk in 1100 pediatric oncology patients with fever and neutropenia" Cancer, 92:909-913, 2001
Aquino VM, Sandler ES, Mustafa MM, Steele J, Buchanan GR, "A prospective double blind randomized trial of urokinase flushes to prevent bacteremia due to luminal colonization of central venous catheters." J Pediatr Hematol Oncol, 24:710-713, 2002
Aquino VM, Douek DC, Berryman B, Johnson M, Jain V, Collins RH, "Evaluation of thymic output by measurment of T-cell-receptor gene rearrangement excisional circles (TREC) in patients who have received fludarabine" Leukemia and Lymphoma, 44:343-348, 2003
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