Education: 1990, B.S. in Biology, University of Science and Technology of China 1997, Ph.D. in Biology, City University of New York
Professional Experiences: 1/07 to Present, Instructor, Department of Surgery, UT Southwestern Medical Center 11/03-12/06, Research Scientist, Department of Surgery, UT Southwestern Medical Center 02/02-07/03, Scientist, Reata Pharmaceuticals, Inc., Dallas, TX 06/99-01/02, Scientist, Department of Inflammation Diseases, Biogen, Inc., Cambridge, MA. 12/96-05/99, Postdoctoral Fellow, Center for Blood Research, Harvard Medical School, Boston, MA.
Professional Memberships 06/05-Present Shock Society 02/06-Present Surgical Infection Society 01/06-Present Society of Critical Care Medicine
Peer-reviewed Publications (in chronological order): 1. Jiang YW, Song J, Zang Q, Foster DA. Phosphatidylcholine-specific phospholipase D activity is elevated in v-Fps-transformed cells. Biochem Biophys Res Commun. 1994 Sep 15;203(2):1195-2003. 2. Zang Q, Frankel P, Foster DA. Selective activation of protein kinase C isoforms by v-Src. Cell Growth Differ. 1995 Nov;6(11):1367-73. 3. Jiang Y, Lu Z, Zang Q, Foster DA. Regulation of phosphatidic acid phosphohydrolase by epidermal growth factor-Reduced association with the EGF receptor followed by increased association with protein kinase C?O. J Biol Chem. 1996 Nov 22;271(47):29529-32. 4. Zang Q, Lu Z, Curto M, Barile N, Shalloway D, Foster DA. Association between v-Src and protein kinase C?O in v-Src-transformed fibroblasts. J Biol Chem. 1997 May 16;272(20):13275-80. 5. Lu Z, Hornia A, Jiang YW, Zang Q, Ohno S, Foster DA. Tumor promotion by depleting cells of protein kinase C ?O. Mol Cell Biol. 1997 Jun;17(6):3418-28. 6. Huang C, Zang Q, Takagi J, Springer TA. Structural and functional studies with antibodies to the integrin ?O2 subunit. A model for the I-like domain. J Biol Chem. 2000 Jul 14;275(28):21514-24. 7. Zang Q, Lu C, Huang C, Takagi J, Springer TA. The top of the inserted-like domain of the integrin lymphocyte function-associated antigen-1 ?O subunit contacts the ?? subunit ?O-propeller domain near ?O-sheet 3. J Biol Chem. 2000 Jul 21;275(29):22202-12. 8. Zang Q, Springer TA. Amino acid residues in the PSI domain and cysteine-rich repeats of the integrin beta2 subunit that restrain activation of the integrin ??(X)?O(2). J Biol Chem. 2001 Mar 9;276(10):6922-9. 9. Lu C, Shimaoka M, Zang Q, Takagi J, Springer TA. Locking in alternate conformations of the integrin ??L?O I domain with disulfide bonds reveals functional relationships among integrin domains. Proc Natl Acad Sci U S A. 2001 Feb 27;98(5):2393-8. 10. Schageman JJ, Ferguson DA, Zang Q, Spencer JA, Huff JW, Graff JM, Lian Y, Garner HR, Pertsemlidis A. Reading the fine print of the human genome. IEEE Eng Med Biol Mag. 2003 Mar-Apr;22(2):105-8. 11. Ferguson DA, Muenster MR, Zang Q, Spencer JA, Schageman JJ, Lian Y, Garner HR, Gaynor RB, Huff JW, Pertsemlidis A, Ashfag R, Schorge, J, Becerra C, Williams NS, Graff JM. Selective identification of secreted and transmembrane breast cancer markers using Escherichia coli ampicillin secretion trap. Cancer Res. 2005 Sep 15;65(18):8209-17. 12. Zang Q, Maass DL, White J, Jureta W. Horton JH. Cardiac Mitochondrial Damage and Loss of ROS Defense after Burn Injury: the Beneficial Effects of Antioxidant Therapy. Manuscript reviewed and under revision. J. Appl. Physiol. 2007 Jan;102(1):103-12. 13. Zang Q, Maass DL, Tsai SJ, Horton JW. Cardiac Mitochondrial Damage and Inflammation Responses in Sepsis. Surg Infect (Larchmt). 2007 Feb;8(1):41-54.
Patent: Graff, Jonathan M; Ferguson, Deborah A.; Zang, Qun; Spencer, Jeffrey A. Markers for diagnosing and treating breast and ovarian cancer. United States Patent Application 20050208499
