NAME: Radu Marches, Ph.D. POSITION TITLE: Assistant Professor, Cancer Immunobiology Center INSTITUTION AND LOCATION DEGREE, YEARS, FIELD OF STUDY B.S. 1982 - Bucharest Polytechnic Institute - Biochemistry Ph.D. 1992 - Institute of Biochemistry - Biochemistry
1993 - 1996 - Research Associate - UT Southwestern Medical 1996 -1997 - Assistant Instructor - UT Southwestern Medical 1997 - Present - Assistant Professor - UT Southwestern Medical
1. Racila, E., R. Hsueh, R. Marches, T.F. Tucker, P.H. Krammer, R.H. Scheuermann, and J.W. Uhr. 1996. Tumor dormancy and cell signaling: Anti-5-induced apoptosis in human B-lymphoma cells is not caused by an APO-1 - APO-1 ligand interaction. Proc. Natl. Acad. Sci. USA 93: 2165-2168. 2. Scheuermann, R.H., E. Racila, R. Hsueh, R. Marches, T. Tucker, and J.W. Uhr. 1996. Growth control and dormancy in malignant lymphoma. IN: Premalignancy and Tumor Dormancy (E. Yefenof and R.H. Scheuermann, Eds.), R.G. Landes Company, Austin, pp. 123-136. 3. Uhr, J.W., R. Marches, E. Racila, T.F. Tucker, R. Hsueh, N.E. Street, E.S. Vitetta, and R.H. Scheuermann. 1996. Role of antibody signaling in inducing tumor dormancy. Adv. Exp. Med. Biol. 406: 69-74. 4. Vitetta, E.S., T.F. Tucker, E. Racila, Y.-W. Huang, R. Marches, N. Lane, R. Scheuermann, N.E. Street, T. Watanabe, and J.W. Uhr. 1997. Tumor dormancy and cell signaling. V. Regrowth of the BCL1 tumor after dormancy is established. Blood, 89:4425-4436. 5. Marches, R., R.H. Scheuermann, and J.W. Uhr. 1998. Cancer dormancy: Role of cyclin-dependent kinase inhibitors in induction of cell cycle arrest mediated via membrane IgM. Cancer Res. 58: 691-697. 6. Marches, R., R. Hsueh, and J.W. Uhr. 1999. Cancer dormancy and cell signaling: Induction of p21WAF1 initiated by membrane IgM engagement increases survival of B lymphoma cells. Proc. Natl. Acad. Sci. USA 96: 8711-8715. 7. Marches, R. E.S Vitetta, and J.W. Uhr. 2001. A role for intracellular pH in membrane IgM-mediated cell death of human B lymphomas. Proc. Natl. Acad. Sci. USA 98: 3434-3439. 8. Uhr, J.W. and R. Marches. 2001. Dormancy in a model of murine B cell lymphoma. Semin. Cancer Biol. 11: 277-283. 9. Spiridon, C.I., M.A. Ghetie, J. Uhr, R. Marches, J.L. Li, G.L. Shen, and E.S. Vitetta. 2002. Targeting multiple Her-2 epitopes with monoclonal antibodies results in improved antigrowth activity of a human breast cancer cell line in vitro and in vivo. Clin Cancer Res. 8: 1720-1730.
