Magnetic Resonance Research

Magnetic Resonance (MR) research in the Department of Radiology at UT Southwestern Medical Center brings together a number of internationally recognized laboratories and investigators with a strong record of leadership in the basic development and clinical applications of MR imaging and spectroscopy.

This group strives to carry out fundamental research that leads either to the development of new techniques and interventions using MR or to an improved understanding of the pathophysiology of disease for diagnosis and treatment. One of our most important goals is to translate these advances rapidly into clinical practice, thereby improving the fundamental capabilities of diagnostic and theranostic imaging and improving the standard of patient care.

The overarching theme connecting our various research interests – a theme shared with the clinical MRI Section – is a push to obtain comprehensive structural/anatomic information as rapidly as possible so that the time saved may be invested in the determination of tissue and organ function using quantitative imaging.

Current projects in our collective research program broadly comprise rapid imaging through novel technical advancements, including whole body cancer screening and staging, improving tissue and organ characterization using perfusion, diffusion and contrast-enhanced kinetics, exploring endogenous contrast mechanisms using CEST, quantifying fat and iron in the liver, as well as metabolite and multinuclear imaging and spectroscopy. 

Translating these techniques into high-field MR at 7 Tesla for improved image quality and tissue/organ characterization is another evolving avenue of research.