Cyclotron and Radiochemistry

The Cyclotron and Radiochemistry Program is a UT Southwestern Medical Center-wide effort to develop the full capability of nuclear imaging, namely radioisotope-based imaging, for noninvasive assessment of physiological processes and abnormalities in animal models and in humans. Its mission is to facilitate translation of basic biomedical research into clinical practice.

The Cyclotron and Radiochemistry facility should be fully operational by the end of 2014. Equipped with a GE PETrace cyclotron (16.5 MeV and 130 µA of proton beam), the facility will be able to produce [15O], [13N], [11C], [18F] and other longer-lived radioisotopes (64Cu, 86Y, and 89Zr) at highly specific radioactivity for the development and delivery of a wide range of PET probes in a cGMP-certified radiopharmacy and production laboratory. 

While the facility remains under construction, the Program has already established a preclinical nuclear imaging laboratory that's equipped with two state-of-the-art small animal nuclear imaging scanners (Siemens Inveon PET/CT Multimodality System and NanoSPECT/CT Plus system) and a fully operational radiochemistry research facility.