Researchers find novel function for old protein in work that could lead to new ways to protect brain from stroke damage

Yingfei Wang, Ph.D.
Yingfei Wang, Ph.D.

One particular protein is the final executioner of events that result in the death of brain cells during stroke, researchers from UT Southwestern Medical Center and their collaborators report. This finding could ultimately lead to new ways to protect against brain damage.

Researchers discovered that the protein, macrophage migration inhibitory factor (MIF), breaks the cell’s DNA, resulting in brain cell death.

Yingfei Wang, Ph.D., Assistant Professor of Pathology and of Neurology and Neurotherapeutics at UT Southwestern, was lead author of the study.