Professor and Chair of Pathology
Research Interests: Post-transcriptional gene regulation and signaling in the immune and nervous system.
Faculty Investigative Pathology
Our diverse group of faculty share a common goal of probing fundamental mechanisms of disease through basic and applied investigations. Dominant themes of research include cancer biology and immunology, with expertise in aging, DNA repair, developmental and reproductive biology, bioinformatics, and signal transduction. Labs are staffed by accomplished graduate and medical students, postdoctoral scholars, technical personnel, and physicians. Highlights of the division include:
- Ties between the labs are strengthened by an annual retreat, as well as bimonthly seminars including the departmental seminar series and a pathophysiology of disease seminar given by pathology residents
- Wide array of departmental core facilities including molecular histology (Richardson) and flow cytometry
Numerous opportunities exist for collaborations aimed at maximizing the interactions between basic scientists and physicians in the elucidation of mechanisms of disease. We invite you to explore the individual webpages of our investigative faculty.
Adjunct Professor
Research Interests: Studies of murine bone pathology marrow transplantation (BMT) and natural killer (NK) cells.
Professor
Research Interests: Neuromuscular pathology, electron microscopy, and the evaluation of phenotypic alterations in genetically engineered mouse models.
Associate Professor
Director, Investigative Pathology
Research Interests: Understanding the molecular basis of reproduction and diseases of the reproductive tract, with an emphasis on the stem cells that drive these processes.
Assistant Professor
Chief of Microbiology, Children’s Medical Center
Research Interests: Development of molecular tools for the rapid diagnosis of infectious diseases. This includes implementation and application of new and emerging technologies that promise to improve our ability to diagnose disease in a rapid manner.
Assistant Professor
Research Interests: Immunology of multiple sclerosis, autoimmune disease, and transplantation.
Professor
Research Interests: Understanding the molecular mechanism of DNA repair and mutagenesis in eukaryotes and the roles of these processes in cancer associated with both spontaneous DNA damage and that caused by environmental carcinogens.
Assistant Professor
Associate Dean of Medical Student Research
Research Interests: Genetic and molecular underpinnings of childhood cancer. To address these issues, we are presently utilizing multiple animal model systems (including invertebrate and mammalian models) to dissect the biology of the most common soft-tissue sarcoma of childhood- the skeletal muscle-type tumor rhabdomyosarcoma.
Professor
Research Interests: Evaluation of new diagnostic tests in clinical microbiology.
Professor
Research Interests: Long term goals of Dr. Gazdar’s research efforts are to determine the molecular and genetic basis of human cancers, and to develop molecular insights to provide prognostic and diagnostic therapies in the treatment of human cancers.
Clinical Professor
Research Interests: Gastritis (Helicobacter pylori) and its associations, Eosinophilic esophagitis and Patho-epidemiologic studies based on analyses from large databases.
Ibrahim A. Hashim, M.Sc., Ph.D.
Professor
Chief of Clinical Pathology
Director of Clinical Chemistry
Research Interests: Elucidating the role of inflammatory cytokines and their mediators in the pathogenesis of heatstroke, trauma, and meningitis. I am also interested in proteomics and molecular heterogeneity of prolactin and of cytokines and on posttranslational modifications affecting their biological and immunological activities.
Associate Professor
Research Interests: Brain tumors and neuropathology.
Assistant Professor
Research Interests: Study of Huntington disease, frontotemporal dementia, multiple sclerosis, autism spectrum disorders, and inflammatory myopathies.
Associate Professor
Director of Autopsy, Children’s Medical Center
Research Interests: Perinatal and placental pathology and autopsy pathology.
Professor
Director of Chemistry, Children’s Medical Center
Research Interests: Inborn errors of metabolism, especially disorders of fatty acid metabolism.
Professor
Research Interests: Elucidating functions of Klotho and its related protein beta-Klotho.
Assistant Professor
Director of Tissue Repository
Research Interests: Identifying biomarkers of DCIS progression, and studying gastrointestinal and liver pathology pcancers using clinically annotated biospecimens.
Professor
Chief of Pathology Services, Parkland Memorial Hospital
Research Interests: General surgical pathology and urologic pathology.
Associate Professor
Director of Hematopathology
Research Interests: Translational studies involving myeloid neoplasms and plasma cell myeloma.
Assistant Professor
Director of Tissue and Transfusion Services, Children’s Medical Center
Research Interests: Clinical and translation applications of therapeutic apheresis and pediatric transfusion medicine.
Associate Professor
Research Interests: Development of molecular diagnostic assays and their applications in oncology and infectious disease.
Adjunct Professor
Research Interests: Development and elucidation of animal models for human diseases.
Assistant Professor
Clinical Director of Advanced Diagnostics, Children’s Medical Center
Research Interests: Development of clinical laboratory technologies with a focus on gastrointestinal and liver pathology and pediatric diseases.
Assistant Professor
Research Interests: Proteomics, mass spectrometry, and protein array methods development; mechanisms in autoimmune/neurodegenerative disorders and cancer epigenetics.
Assistant Professor
Research Interests: Autoimmune hepatitis; acute liver failure; pancreatic neoplasm; inflammatory bowel disease.
Associate Professor
Research Interests: To explore prognostic and predictive tumor biomarkers for breast cancer byimmunohistochemistry and molecular techniques.
Associate Professor
Interim Chief of Pediatric Pathology, Children’s Medical Center
Research Interests: Pediatric solid tumors
James Richardson, D.V.M., Ph.D.
Professor
Director of Sophomore Medical School Course
Research Interests: Analysis of murine phenotypes, comparative pathology, and developmental biology.
Richardson Lab/Molecular Pathology
Professor
Chief of Clinical Laboratory Services, UTH
Research Interests: TTP platelet function disorders, HIT, management of anticoagulation related bleeding, thrombophilia, and patient blood management.
Associate Professor
Research Interests: Related to breast cancer biomarkers and the impact of neoadjuvant chemotherapy on biomarker expression and the biology of HER2positive breast cancer.
Associate Professor
Research Interests: Molecular biology of cell surface molecules governing adhesion to and transmigration through vascular endothelium.
Associate Professor
Research Interests: Molecular genetics of DNA polymorphisms of value in forensic evidence examinations.
Professor
Director of Microbiology, Parkland Memorial Hospital
Research Interests: Define the prevalence of infection due to Trypanosoma cruzi (Chagas Disease) in the human population of the Toledo District of Belize.
Associate Professor
Associate Director of Anatomic Pathology
Medical Director of Histology, IHC Laboratories and Renal Pathology
Director of General Surgical Pathology – Zale Lipshy University Hospital
Research Interests: Immunopathology of solid organ transplantation. More specifically, my current work is looking at mechanisms involved in the development of chronic allograft injury, including alloimmunity, autoimmnunity, and non-immune related allograft injury.
Professor
Director of Neuropathology
Research Interests: Neurodegenerative diseases and forensic neuropathology
