Humoral Immunology

Resident training in Humoral Immunology is accomplished through formal didactic lectures and a one-month immunology rotation for the junior-year residents. This provides residents with an opportunity to learn immunology while getting involved in the day-to-day operations of a busy clinical immunology laboratory, located in Parkland Memorial Hospital.

On the first day of the rotation the residents receive a CD with the objectives, plan, and all the reading material for the rotation. During the first week of the rotation the residents observe bench work and rotate through all the different benches in the laboratory, interacting one-on-one with the technologist performing the tests to understand the method and procedure.

Each afternoon the resident is also expected to analyze immunofluorescence patterns on slides from patients with autoimmune or infectious diseases. The residents accompany the director of the clinical laboratory in daily rounds/didactic meetings at 1 p.m.

The resident is also expected to:

  • Interact with the laboratory technologists, learn the practical issues, apply the theoretical knowledge, and interact with clinicians regarding appropriate assays
  • Gather clinical data about patients tested for anti-parietal cell, mitochondrial, and smooth muscle antibodies, look at the slides, and sign them out with M. Qasim Ansari, M.D., every Thursday afternoon
  • Make weekly (Wednesdays) informal presentations to the laboratory staff regarding abnormal clinical results obtained that week
  • Read selected assignments from the reading list provided, then discuss daily topics with the faculty
  • Function as consultants to clinical faculty with questions concerning appropriate test selection and use of "send out" tests
  • Attend the Clinical Pathology Lectures, Clinical Pathology Rounds, and Internal Medicine Grand Rounds

At the end of the rotation, the residents also make a formal presentation to the laboratory director and laboratory personnel, and may also be called upon to present at the Clinical Pathology Rounds on an immunology-related topic or participate in a project in the laboratory.

At the end of the rotation, a quiz consisting of 50 immunology questions will be administered to determine the level of resident expertise. An exit interview with the faculty will follow with formal evaluation.

Duration

One month

Prerequisites

None

Objectives

Conferences

  • Daily sign-out of immunology reports
  • Weekly case discussions
  • Weekly Clinical Pathology rounds
  • Weekly Internal Medicine Grand Rounds
  • Weekly administrative meetings with lab manager and pathologist

Basic Reading

Selected articles in CD format are provided to the resident on the first day of the Humoral Immunology rotation. A list of other reading material including book chapters is provided on the CD.