Research Projects
Listed below are examples of several current basic science projects underway. The ”Read more” links at the end of each project listed will open a PDF in a new window listing a summary, methods, results and a brief discussion of the project.
Elimination of Mitochondria Related Bim/Bid Proteins Reduces Chondrocyte Apoptosis After Mechanical Injury
Eisner, E1; Shelton, JM1; Davis, CG2; 1 J; McClure, S1; Chen, CT1; Hotchkiss, RS2; Borrelli, J1 UT Southwestern Medical Center, Dallas TX; 2Washington University, St. Louis, MO Read more
The Role of G Protein-coupled Estrogen Receptor 1 in the Fracture Healing of Normal and Oophorectomized Mice
Bryan Reyes, Brigham Au, MD, James Phelps, MD, Orhan Oz, PhD, Rahul Banerjee, MD Read more
Single Impact Load Causes Post Traumatic Osteoarthritis in Rabbits
Joseph Borrelli, Jr., MD Read more: Part 1 and Part 2
Effect of BMP-2 and BMP-7 on Articular Cartilage Following an Impact Load
Paul Chin, MD, PhD, Chris Chen, PhD, Timothy Brown, Joseph Borrelli, Jr., MD Read more
A Biomechanical Analysis of Biotenodesis Screw Versus Bone Tunnel Methods in Flexor Hallucis Longus Tendon Transfer for Chronic Achilles Tendon Ruptures
B. Christian Balldin, MD, Jacob R. Zide, MD, Christopher C.T. Chen, PhD, George T. Liu, DPM Read more
Impaired Healing of Rotator Cuff Correlates with Altered MMP and Collagen Expression of Supraspinatus Tendon
Shindle, M1;Robertson, C1;Demetrakopoulos D1;Cordasco F1; Rodeo SA1;Warren R F1; Chen, CT2 1Hospital for Special Surgery, New York, NY, 2UT Southwestern, Dallas, TX Read more