Recent Publications

Agrawal D, Rockey DC. Sterile water in endoscopy: habit, opinion, or evidence. Gastrointest Endosc. (2013) 78(1):150-2.

Arora G, Gupta S, Rockey D. Gastrostomy score for 30-day mortality: good start but way to go. Gastrointest Endosc. (2012) Jul;76(1):224-5.

Bajaj JS, O’Leary JG, Wong F, Reddy KR, Subramanian R, Brown G, Noble, NA, Thacker LR, Kamath PR. Second infections independently increase mortality in hospitalized patients with cirrhosis: the North American consortium for the study of end-stage liver disease (NACSELD) experience.  Hepatology (2012) Dec;58(6):2328-35.

Mello M, Weideman R, Weideman M, Little B, Cryer B, Brown GR. Proton pump inhibitors increase the incidence of bone fractures in hepatitis C patients. Dig Dis Sci (2012) Sep;57(9):2416-22.

Browning JD, Burgess SC. Use of (2)H(2)O for estimating rates of gluconeogenesis: determination and correction of error due to transaldolase exchange. Am J Physiol Endocrinol Met. (2012) Dec 1;303(11):E1304-12

Satapati S, Sunny NE, Kucejova B, Fu X, He T, Mendez-Lucas A, Shelton JM, Perales JC, Browning JD, Burgess SC. Elevated TCA cycle function in the pathology of diet-induced hepatic insulin resistance and fatty liver. J Lipid Res. (2012) 53:1080-1092.

Turer AT, Browning JD, Ayers CR, Das SR, Khera A, Vega GL, Grundy SM, Scherer PE. Adiponectin as an independent predictor of the presence and degree of hepatic steatosis in the Dallas Heart Study. J Clin Endocrinol Metab. (2012) 97:E982-E986.

Colleran A, Collins P, O'Carroll C, Ahmed A, Mao X, McManus B, Kiely PA, Burstein E, Carmody RJ. Deubiquitination of NF-κB by ubiquitin-specific protease-7 promotes transcription. Proc Natl AcadSci USA. (2013) 110: 618-623.

Ziesche E, Kettner-Buhrow D, Weber A, Wittwer T, Jurida L, Soelch J, Mueller H, Newel D, Kronich P, Schneider H, Dittrich-Breiholz O, Bhaskara S, Hiebert S, Hottiger M, Li H, Burstein E, Schmitz L, Kracht M. The coactivator role of histone deacetylase 3 in IL-1-signaling involves deacetylation of p65 NF-κB. Nucleic Acids Res. (2013) 41:90-109.

Li H, Wittwer T, Weber A, Schneider H, Moreno R, Maine GN, Kracht M, Schmitz ML, Burstein E. Regulation of NF-κB activity by competition between RelA acetylation and ubiquitination. Oncogene. (2012) 31: 611-623.

Feagins LA, Iqbal R, Harford WV, Halai A, Cryer BL, Dunbar KB, Davila RE, Spechler, SJLow rate of postpolypectomy bleeding among patients who continue thienopyridine therapy during colonoscopy. Clin Gastrenterol Hepatol. (2013) Feb 9. [Epub ahead of print] PMID: 23403011

Cryer B, Li C, Simon LS, Singh G, Stillman MJ, Berger MF. GI-REASONS: A novel 6-month, prospective, randomized, open-label, blinded endpoint (PROBE) trial. Am J Gastrenterol. (2013) Mar;108(3):392-400.

Uddin FS, Iqbal R, Harford WV, Dunbar, KB, Cryer BL, Spechler SJ, Feagins LAProne positioning of obese patients for colonoscopy results in shortened cecal intubation times: a randomized trial. Dig Dis Sci. (2013) Mar;58(3):782-7.

Urrunaga NH, Singal AG, Cuthbert JA, Rockey DC. Hemorrhagic ascites. Clinical presentation and outcomes in patients with cirrhosis.  J Hepatol (2013) Jun:58(6): 1113-8

Singal AG, Rahimi R, Clark C, Ma Y, Cuthbert JA, Rockey DC and Amarasingham R. An automated model using electronic medical record data identifies patients with cirrhosis at high risk for readmission. Clin Gastroenterol Hepatol (2013) (in press)

Feagins LA, Melton SD, Iqbal R, Dunbar KB, Spechler SJ. Clinical implications of histologic abnormalities in colonic biopsy specimens from patients with ulcerative colitis in clinical remission. Inflam Bowel Dis (2013) Jun;19(7):1477-82.

Jodorkovsky D, Gearhart SL, Dunbar KB, Stein E, Clarke, JO. Biofeedback therapy for defecatory dysfunction: "real life" experience. J Clin Gastro (2013) Mar;47(3):252-5.

Singal A , Chan V, Getachew Y, Guerrero R , Reisch J, Cuthbert J. Predictors of liver transplant eligibility for patients with hepatocellular carcinoma in a safety net hospital. Dig Dis Sci. (2012) Feb;57(2):580-6.

Grant LM, Kleiner DE, Conjeevaram HS, Vuppalanchi R, Lee WM. Clinical and histological features of idiosyncratic acute liver injury caused by temozolomide.  Dig Dis Sci. (2013) May;58(5):1415-21.

Ding B, Wang W, Selvakumar T, Xi HS, Zhu H, Chow CW, Horton JD, Gronostajski RM, Kilpatrick RM. (2013). Temporal regulation of nuclear factor one occupancy by calcineurin/NFAT governs a voltage-sensitive developmental switch in late maturing neurons. J Neurosci. 33:2860-2872.

Deng Y, Wang ZV, Tao C, Gao N, Holland WL, Ferdous A, Repa JJ, Liang G, Ye J, Lehrman MA, Hill JA, Horton JD, Scherer PE. The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism. J Clin Invest. (2013) Jan 2;123(1):455-68.

Fabbrini E, Higgins PB, Magkos F, Bastarrachea RA, Voruganti VS, Comuzzie AG, Shade RE, Gastaldelli A, Horton JD, Omodei D, Patterson BW, Klein S. Metabolic response to high-carbohydrate and low-carbohydrate meals in a nonhuman primate model. Am J Physiol Endocrinol Metab. (2013) Feb 15;304(4):E444-51

Cheng E, Zhang X, Huo X, Yu C, Zhang Q, Wang DH, Spechler SJ, Souza RFOmeprazole blocks eotaxin-3 expression by oesophageal squamous cells from patients with eosinophilic oesophagitis and GORDGut. (2013) Jun;62(6):824-32.

Sussman DA, Kubiliun N, Mulani PM, Chao J, Gillis CA, Yang M, Lu M, T Abreu M. Comparison of medical costs among patients using adalimumab and infliximab: a retrospective study (COMPAIRS). Inflamm Bowel Dis. (2012) Nov;18(11):2043-55.

Kleiner DE, Chalasani NP, Lee WM, Fontana RJ, Bonkovsky HL, Watkins PB, Hayashi PH, Davern TJ, Navarro V, Reddy R, Talwalkar JA, Stolz A, Gu J, Barnhart H, Hoofnagle JH. Hepatic histological findings in suspected drug-induced liver injury: Systematic evaluation and clinical associations. Hepatology. (2013) Aug 28, in press.

Opio CK, Seremba E, Ocama P, Lalitha R, Kagimu M, Lee WMDiagnosis of alcohol misuse and alcoholic liver disease among patients in the medical emergency admission service of a large urban hospital in Sub-Saharan Africa; a cross sectional study. Pan Afr Med J. (2013) May 13;15:23.

Karkhanis J, Verna EC, Chang MS, Stravitz RT, Schilsky M, Lee WM, Brown RS Jr; the Acute Liver Failure Study Group. Steroid use in acute liver failure.  Hepatology. (2013) Aug 8, in press.

Stravitz RT, Sanyal AJ, Reisch J, Bajaj JS, Mirshahi F, Cheng J, Lee WM; Acute Liver Failure Study Group. Effects of N-acetylcysteine on cytokines in non-acetaminophen acute liver failure: potential mechanism of improvement in transplant-free survival. Liver Int. (2013) Oct;33(9):1324-31.

Singal AG, Nehra M, Adams-Huet B, Yopp AC, Tiro JA, Marrero JA, Lok AS, Lee WM. Detection of hepatocellular carcinoma at advanced stages among patients in the HALT-C trial: where did surveillance fail? Am J Gastroenterol. (2013) Mar;108(3):425-32.

Jones RD, Repa JJ, Russell DW, Dietschy JM, Turley SDDelineation of biochemical, molecular, and physiological changes accompanying bile acid pool size restoration in Cyp7a1(-/-) mice fed low levels of cholic acid. Am J Physiol Gastrointest Liver Physiol (2012)  303:G263-274.

Buchovecky CM, Turley SD, Brown HM, Kyle SM, McDonald JG, Liu B, Pieper AA, Huang W, Katz DM, Russell DW, Shendure J, Justice MJ. A suppressor screen in Mecp2 mutant mice implicates cholesterol metabolism in Rett syndrome. Nat Genetics  (2013) 45:1013-1020.

Ramirez CM, Lopez AM, Le LQ, Posey KS, Weinberg AG, and Turley SD. Ontogenic changes in lung cholesterol metabolism, lipid content, and histology in mice with Niemann-Pick type C disease. Biochim. Biophys. Acta – Molecular and Cell Biology of Lipids. (2013), in press.

Waljee AK, Mukherjee A, Singal AG, Zhang Y, Warren J, Balis U, Marrero J, Zhu J, Higgins PD. Comparison of imputation methods for missing laboratory data in medicine. BMJ Open. (2013) Aug 1;3(8).

Comunale MA, Wang M, Anbarasan N, Betesh L, Karabudak A, Moritz E, Devarajan K, Marrero J, Block TM, Mehta A. Total serum glycan analysis is superior to lectin-FLISA for the early detection of hepatocellular carcinoma. Proteomics Clin Appl. (2013) Jul 16. doi: 10.1002/prca.201200125. [Epub ahead of print]

Lamontagne A, Long RE, Comunale MA, Hafner J, Rodemich-Betesh L, Wang M, Marrero J, Di Bisceglie AM, Block T, Mehta A. Altered functionality of anti-bacterial antibodies in patients with chronic hepatitis C virus infection. PLoS One. (2013) June 4;8(6) e64992.

Marrero JA. Multidisciplinary management of hepatocellular carcinoma: where are we today? Semin Liver Dis.( 2013) Feb;33 Suppl 1:S3-S10.

Salgia RJ, Singal AG, Fu S, Pelletier S, Marrero JAImproved post-transplant survival in the United States for patients with cholangiocarcinoma after 2000.  Dig Dis Sci. (2013) Mar 16. [Epub ahead of print]

Padhya KT, Marrero JA, Singal AGRecent advances in the treatment of hepatocellular carcinoma.  urr Opin Gastroenterol. (2013) May;29(3):285-92.

Mayorga CA, Rockey DC. Clinical utility of a standardized electronic order set for the management of acute upper gastrointestinal hemorrhage in patients with cirrhosis. Clin Gastroenterol Hepatol. (2013) Apr 29. S1542-3565(13)00581-8.

Yu C, Zhang Q, Zhang HY, Zhang X, Huo X, Cheng E, Wang DH, Arbiser JL, Spechler SJ, Souza RFTargeting the intrinsic inflammatory pathway: honokiol exerts proapoptotic effects through STAT3 inhibition in transformed Barrett's cells. Am J Physiol Gastrointest Liver Physiol. (2012) Sep 1;303(5):G561-9.

Dunbar KB, Spechler SJThe risk of lymph-node metastases in patients with high-grade dysplasia or intramucosal carcinoma in Barrett's esophagus: A systematic review. Am J Gastroenterol (2012); 107:850-62.