Centers Affiliated with Internal Medicine

As part of one of the world’s foremost research institutions, the Department of Internal Medicine at UT Southwestern Medical Center conducts basic science and clinical research with the goal of bringing the latest discoveries from the “bench to the bedside.” We take a multidisciplinary approach to research, fostering an environment for physicians, scientists, and students that is both collaborative and cooperative.

Basic and clinical studies in many fields help UT Southwestern deliver the future of medicine, today, by working at the leading edge of research. Our discoveries make a difference.

Our research is supported by funding from major organizations, including the National Institutes of Health, Department of Veterans Affairs, American Heart Association, March of Dimes, National Kidney Foundation, and many more.

Center for Autophagy Research

UT Southwestern's Center for Autophagy Research uses state-of-the-art genetic, biochemical, and cell biological approaches to understand the central role that autophagy, a lysosomal degradation pathway, plays in physiology and human disease. The Center provides a stimulating scientific environment for investigators with diverse areas of expertise to discover the mechanisms by which autophagy functions in development, tissue homeostasis, innate immunity, metabolism, neurodegenerative diseases, aging, and cancer biology.

Hypothalamic Research Center

Together with the Taskforce on Obesity Research at UT Southwestern (TORS), faculty and staff within Hypothalamic Research hope to make discoveries that will help combat the growing problems of obesity and diabetes. Hypothalamic Research is in the Department of Internal Medicine at UT Southwestern, but also includes investigators from several other clinical and basic science areas throughout the Medical Center.

George M. O’Brien Kidney Research Core Center

The O'Brien Kidney Research Center, under the Division of Nephrology, supports research in the areas of kidney development and genetics, renal physiology, and chronic kidney disease that is conducted at UT Southwestern, neighboring institutions in North Texas, and the greater nephrology community in the U.S. and worldwide.

Charles and Jane Pak Center for Mineral Metabolism and Clinical Research

The Mineral Metabolism Clinic, part of Mineral Metabolism, specializes in many various mineral metabolism diseases such as osteoporosis, osteomalacia, Paget's disease, hyperparathyroidism, acid base bone metabolism, nephrolithiasis, kidney stone disease and prevention, and calcium disorders.

Touchstone Diabetes Center

The Touchstone Diabetes Center, under the Division of Endocrinology, is devoted to the study of the cells and tissues that are either contributing to or are affected by diabetes and its co-morbidities. 

Multidisciplinary Centers

The Centers listed below conduct clinical and basic research involving faculty members from the Department of Internal Medicine and a variety of other departments and programs.

Center for Human Nutrition

Faculty involved with UT Southwestern’s Center for Human Nutrition are devoted to discovering, teaching, and working collaboratively with fellow researchers. As clinical investigators, their mission is to understand the study of abnormal metabolism and to draw out the contributions of nutrition and genetics in human beings.

Center for Patient-Centered Outcomes Research

The UT Southwestern Center for Patient-Centered Outcomes Research (PCOR) was established at UT Southwestern in October 2013 through a grant by the Agency for Healthcare Research and Quality (AHRQ). The Center aims to increase the capacity of UT Southwestern researchers in patient-centered outcomes research (PCOR) and comparative effectiveness research (CER).

Esophageal Diseases Center

The Esophageal Diseases Center (EDC) is devoted to conducting innovative, translational research in a multidisciplinary setting in order to advance understanding of esophageal diseases, and to improve the treatment of patients with those diseases. The faculty of the EDC includes gastroenterologists (adult and pediatric), surgeons, oncologists, and pathologists devoted to the study of esophageal diseases.

Harold C. Simmons Comprehensive Cancer Center

The Harold C. Simmons Comprehensive Cancer Center is a multidisciplinary program responsible for the cancer care and cancer research conducted at UT Southwestern Medical Center. 

Eugene McDermott Center for Human Growth and Development

The McDermott Center provides expertise and resources for both clinicians and basic scientists to identify genes and sequence variation contributing to human diseases and traits.