Faculty and Research
Chad Brautigam, Ph.D. • Email • Lab Website
Chad’s lab uses biophysical methods to study protein:protein and protein:ligand interactions. He is also working to improve the presentation and analysis of biophysical data.
Kevin Gardner, Ph.D. • Email • Lab Website
The Gardner lab studies the biophysical and biochemical basis of environmental sensing domains, exploring natural regulation, and developing methods of artificial control.
Elizabeth Goldsmith, Ph.D. • Email • Lab Website
Betsy's lab studies how proteins are regulated by conformational changes, focusing on protein kinases and using crystallography, NMR, mass spectrometry, and biochemistry.
Nick Grishin, Ph.D. • Email • Lab Website
We work at the interface of biology, computer science, mathematics, and physics. Our group specializes in computational biology of proteins and combines sequence and structure analysis with evolutionary considerations to facilitate discoveries of biological significance.
Khuloud Jaqaman, Ph.D. • Email • Lab Website
Khuloud's lab develops integrative approaches combining single-molecule and super-resolution imaging, computational image analysis, and mathematical modeling to investigate the contribution of cell-surface receptor organization and interactions to cell signaling.
Zbyszek Otwinowski, Ph.D. • Email • Lab Website
The main research focus of the Otwinowski lab is on developing computational and statistical methods and protocols for macromolecular structure determination using X-ray crystallography.
Luke Rice, Ph.D. • Email • Lab Website
Luke’s lab studies microtubule dynamics, seeking to discover how complex behavior emerges from the biochemical properties of molecular components.
Jose Rizo-Rey, Ph.D. • Email
Jose’s lab studies the molecular mechanisms of intracellular membrane fusion, with particular focus on neurotransmitter release and its regulation during presynaptic plasticity.
Michael Rosen, Ph.D., Chair • Email • Lab Website
The Rosen lab studies the physical mechanisms of actin regulation. We seek to understand both the structure and dynamics of individual pathway components and also how and why those components are organized into micron-scale cellular assemblies.
Dan Rosenbaum, Ph.D. • Email
Dan's lab studies the structure and function of eukaryotic integral membrane proteins. The goal of his research is to understand how ligands and the membrane environment influence the conformational landscape of key membrane proteins involved in cellular signaling.
Diana Tomchick, Ph.D. • Email • Lab Website
Diana's lab is focused on the relationship of protein structure to biological function, primarily characterized via the technique of protein crystallography. She is also interested in improving protein crystallization techniques, crystallographic data acquisition, and experimental methods of phasing.
Hong Zhang, Ph.D. • Email • Lab Website
Hong's lab studies structure-function of various enzymes and regulators of NAD metabolic pathways and how NAD in turn influences gene expression such as circadian clock-mediated transcription regulation.
