Undergraduate Student Profiles

Each summer, faculty in the Department of Biophysics host a number of undergraduate students from around the country as part of  the SURF and QP-SURF programs. The Department also supports the work of future biophysicists through the Sara and Frank McKnight Undergraduate Prizes in Molecular Sciences, which was created by Steve McKnight, Chair of our sister department of Biochemistry here at UT Southwestern. 

Former Students

Laura Downes

Hometown: Louisville, Kentucky
Undergrad institution: University of Dallas (Physics)
Mentor: Luke Rice, Summer 2012
Project: Dissecting microtubule catastrophe using site-directed ab-tubulin mutants
Current position: Finishing undergrad!


Gregory Knutsen

Hometown: Overland Park, KS
Undergrad Institution: University of Dallas (Physics and Chemistry)
Current position: Baylor College of Dentistry (expected to graduate 5/2013)
Mentor: Mischa Machiu, Summer 2007
Project: Studies of the metal-binding properties of the Tp34 protein from Treponema pallidum in solution and in crystals.
Paper resulting from SURF studies: Brautigam, C.A., Deka, R.K., Ouyang, Z., Machius, M., Knutsen, G., Tomchick, D.R., and Norgard, M.V. (2012). Biophysical and Bioinformatic Analyses Implicate the Treponema pallidum Tp34 Lipoprotein (Tp0971) in Transition Metal Homeostasis. J. Bact. In press.


Nathaniel Schaffer

Nathaniel Schaffer

Hometown: Dallas, TX
Undergrad Institution: Washington University in St. Louis (Mathematics and Chemistry)
Mentor: Mischa Machius, Structural Biology lab, Summer 2006
Project: Studies of substrate binding to P450-BM3.
Paper resulting from SURF studies: Hegde, A., Haines, D.C., Bondlela, M., Chen, B., Schaffer, N., Tomchick, D.R., Machius, M., Nguyen, H., Chowdhary, P.K., Stewart, L., Lopez, C., & Peterson, J.A. (2007). Interactions of Substrates at the Surface of P450s Can Greatly Enhance Substrate Potency. Biochemistry, 46, 14010-14017
Where is he now? UT Southwestern Medical Center, M.D./Ph.D., Dept. of Physiology (expected to graduate 6/2016)