Postdoctoral Position Available

Biochemical and Biophysical investigation of RNA-mediated Gene Regulation

The research group of Yunsun Nam, Ph.D. at UT Southwestern is seeking a postdoctoral scholar. Our laboratory is housed in newly renovated space at the heart of the Cecil H. and Ida Green Center for Reproductive Biology Sciences.

The overarching goal of our group is to elucidate the mechanistic details of RNA-regulated gene expression, by investigating the structure-function relationship of various protein/nucleic acid complexes. We are particularly interested in the gene regulation pathways relevant to mammalian development and cancer. Postdoctoral scholars will have many opportunities to learn the newest methods in biochemistry and biophysics, in addition to working in an exciting, fast evolving area in the field of biological and biomedical sciences. We use various approaches, including X-ray crystallography, NMR spectroscopy, electron microscopy, molecular biology, nucleic acid and protein biochemistry, high throughput sequencing, and mammalian cell-based studies. For more information, please refer to the lab website.   

Candidates must have a Ph.D. degree and a strong background in biochemistry (protein or nucleic acid) and/or structural biology. Interested individuals should submit a CV as a single pdf file, including contact information for three references, by email to Dr. Nam. Yunsun.Nam@UTSouthwestern.edu 

Postdoctoral Fellows

Rustam Ali

Rustam Ali

Hometown: Muzaffarpur, India
Undergrad: School of Biotechnology, Faculty of Engineering Sciences, DAVV, Indore, India (Biotechnology)
Graduate Program: Molecular Biophysics Unit, Indian Institute of Science, Bangalore, India (NMR/Biophysics)
Postdoc Mentor: Mike Rosen
Project: 1) NMR studies of actin monomer dynamics, and their roles in actin filament dynamics; 2) NMR studies of phase separated liquid droplets
Paper: “Methyl labeling and TROSY NMR spectroscopy of proteins expressed in the eukaryote Pichia pastoris”


Lindsay Case

Lindsay Case

Hometown: Rockwall, Texas
Undergrad: Franklin and Marshall College (Biology)
Graduate Program: University of North Carolina, Chapel Hill (Cell and Developmental Biology)
Postdoc Mentor: Mike Rosen
Project: Regulation of integrin clustering and macromolecular complex assembly on supported lipid bilayers
Paper: Coming Soon!


Baoyu Chen

Jonathon Ditlev

Hometown: Bloomington, Minnesota
Undergrad: Calvin College (Biomedical Sciences)
Graduate Program: University of Connecticut Health Center (Biomedical Sciences)
Postdoc Mentor: Mike Rosen
Project: Regulation of the dynamics and stability of supramolecular clusters on artificial membranes
Paper: Coming Soon!


Baoyu Chen

Zhiqiang Hou

Hometown: China
Undergrad: Liaoning University, University of Chinese Academy of Sciences (Biological Science)
Graduate Program: Institute of Biophysics, Chinese Academy of Science. (Biophysics)
Postdoc Mentor: Hong Zhang
Project: Structure and function of circadian clock proteins
Paper: Coming Soon!


Baoyu Chen

Mark Kittisopikul

Hometown: New Lenox, Illinois
Undergrad: University of Chicago (Biological Chemistry, Mathematics)
Graduate Program: UT Southwestern (Systems Microbiology)
Postdoc Mentor: Khuloud Jaqaman
Project: Ultrastructure of the nuclear lamins in the lamina and nucleoplasm
Paper: “Localized cell death focuses mechanical forces during 3D patterning in a biofilm”


Baoyu Chen

Xiaoxia Liu

Hometown: Xiamen, Fujian, China
Undergrad: Xiamen University (Chemistry)
Graduate Program: Xiamen University (Chemical Biology)
Postdoc Mentor: Jose Rizo-Rey
Project: Dissecting the multiple functions of Munc13 in synaptic vesicle fusion
Paper: “Prioritization of charge over geometry in transition state analogues of a dual specificity protein kinase”


Baoyu Chen

Xiaoyan Liu

Hometown: Shanghai, China
Undergrad: East China University of Science and Technology (Biochemistry)
Graduate Program: Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences (Biochemistry and Molecular Biology)
Postdoc Mentor: Hong Zhang
Project: Crystal Study of Brd4 and Circadian-related genes
Paper: Coming Soon!


Baoyu Chen

Chi Pak

Hometown: Dallas, Texas
Undergrad: Baylor University (Neuroscience)
Graduate Program: Colorado State University (Cell and Molecular Biology)
Postdoc Mentor: Mike Rosen
Project: Physical mechanism of liquid-liquid phase separation for an intrinsically disordered protein
Paper: Coming Soon!


Baoyu Chen

Yun-zu Pan

Hometown: Chia-Yi, Taiwan
Undergrad: Institute of Food and Nutrition, Providence University (Science)
Graduate Program: Institute of Bioinformatics and Structural Biology, University of National Tsing-Hua University (Life Science)
Postdoc Mentor: Jose Rizo-Rey
Project: Use of pseudocontact shifts for NMR studies of the neurotransmitter release machinery
Paper: “NMR structure and calcium-binding properties of the tellurite resistance protein TerD from Klebsiella pneumonia”


Dustin Schaffer

Dustin Schaeffer

Hometown: Antioch, California
Undergrad: UC San Diego (Molecular Biology)
Graduate Program: University of Washington (Bioengineering)
Postdoc Mentor: Nick Grishin
Project: Structural classification of protein domains from structures by automated sequences and structure comparison
Paper: Coming soon!


Baoyu Chen

Zhenhua Shao

Hometown: Shandong province, China
Undergrad: Anhui University (Biological Science)
Graduate Program: University of Science and Technology of China (Structural Biology)
Postdoc Mentor: Dan Rosenbaum
Project: Structure study of G-protein coupled receptor
Paper: Coming Soon!


Baoyu Chen

Lijing Su

Hometown: Xiamen, Fujian, China
Undergrad: University of Science and Technology of China (Bioscience)
Graduate Program: UT Southwestern Medical Center (Integrative Biology)
Postdoc Mentor: Hong Zhang and Bruce Beutler
Project: Structural Biology of Toll-like receptors with small molecule agonists
Paper: Coming Soon!


Baoyu Chen

Bradley VanderWielen

Hometown: Gallatin, Tennessee
Undergrad: Pennsylvania State University (Biochemistry)
Graduate Program: University of Cincinnati (Molecular Genetics)
Postdoc Mentor: Luke Rice
Project: Conformation and recognition in microtubule dynamics
Paper: "Transcriptional Repression in the Notch Pathway: thermodynamic characterization of CSL-MINT (msx2-interacting nuclear target protein) complexes"


Jie Yin

Jie Yin

 
Hometown: Wuhan City, China
Undergrad institution: Wuhan University (Biology)
Graduate institution: Institute of Biophysics, Chinese Academy of Sciences, Beijing (Biochemistry and Molecular Biology)
Postdoc Mentor: Daniel Rosenbaum 
Project: G-Protein Coupled Receptor structural biology
Paper: “Crystal structure of the human OX2 orexin receptor bound to the insomnia drug suvorexant”