Research in Biochemistry

Biochemistry at UT Southwestern Medical Center represents a rich variety of diverse disciplines ranging from chemical synthesis and metabolism to structural biology and disease states. Research within the Department of Biochemistry is pursued along three major areas: biochemistry/molecular biology, biophysics and chemistry. A major thread of chemistry links and binds our faculty together within this Department.
Chemical Investigation
Natural Product Isolation and Synthesis
Chuo Chen, Ph.D.
Associate Professor
Jef DeBrabander, Ph.D.
Professor
John MacMillan, Ph.D.
Assistant Professor
Uttam Tambar, Ph.D.
Assistant Professor
Organometallic and Medicinal Chemistry
J. Russell Falck, Ph.D.
Professor
Total Synthesis of Complex Molecules
László Kürti, Ph.D.
Assistant Professor
Joseph Ready, Ph.D.
Associate Professor
Metabolic Research
Amino and Ketoacid Metabolism
David Te-Chao Chuang, Ph.D.
Professor
Richard Max Wynn, Ph.D.
Associate Professor
P450 Metabolism
Ronald Estabrook, Ph.D.
Professor Emeritus
Biology of Glycoconjugates
Jennifer J Kohler, Ph.D.
Assistant Professor
Lipids and Nuclear Hormones
David Mangelsdorf, Ph.D.
Professor
Metabolites of Both Simple and Complex Carbohydrates
Benjamin Tu, Ph.D.
Assistant Professor
Kosaku Uyeda, Ph.D.
Professor
High-Throughput Screening and Small-Molecule Studies
Small-Molecule Isolation and Mechanisms of Action
Michael Roth, Ph.D.
Professor
Bruce Posner, Ph.D.
Associate Professor
Noelle Williams, Ph.D.
Associate Professor
Structure and Function Studies
X-ray Crystallography
Dominika Borek, Ph.D.
Assistant Professor
Chad Brautigam, Ph.D.
Assistant Professor
Johann Deisenhofer, Ph.D.
Professor
Elizabeth Goldsmith, Ph.D.
Professor
Zbyszek Otwinowski, Ph.D.
Professor
Luke Rice, Ph.D.
Assistant Professor
Daniel Rosenbaum, Ph.D.
Assistant Professor
Diana Tomchick, Ph.D.
Professor
Hong Zhang, Ph.D.
Associate Professor
Xuewu Zhang, Ph.D.
Assistant Professor
NMR Structural Analysis
Kevin Gardner, Ph.D.
Professor
Jose Rizo-Rey, Ph.D.
Professor
Michael Rosen, Ph.D.
Professor
Computational Biology
Nick Grishin, Ph.D.
Professor
Molecular Biology/Biochemistry
Gene Regulation
Richard Bruick, Ph.D.
Associate Professor
Cheng-Ming Chiang, Ph.D.
Professor
Masato Kato, Ph.D.
Assistant Professor
Steven McKnight, Ph.D.
Professor
Carole Mendelson, Ph.D.
Professor
Functions for RNA and Nucleic Acids
David Reid Corey, Ph.D.
Professor
Qinghua Liu, Ph.D.
Associate Professor
Signaling Mechanisms
Marie-Alda Gilles-Gonzalez, Ph.D.
Associate Professor
Kim Orth, Ph.D.
Professor
Vanessa Sperandio, Ph.D.
Professor
Disease States Studies
The Role of Oncogenes in Producing Cancer
Robert Hammer, Ph.D.
Professor
Molecular Engineering of Photonic Probes
Wen-Hong Li, Ph.D.
Associate Professor
Peptidomimetics
Gomika Udugamasooriya, Ph.D.
Assistant Professor