Recent Publications from AIRC Staff and Collaborators

  • 2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas, C Choi, SK Ganji, RJ DeBerardinis, KJ Hatanpaa, D Rakheja, Z Kovacs, X Yang, T Mashimo, JM Raisanen, I Marin-Valencia, JM Pascual, CJ Madden, BE Mickey, CR Malloy, R Bachoo & EA Maher, Nature Medicine, 18: 624-629 (2012).
  • A Preliminary Investigation of Corpus Callosum and Anterior Commissure Aberrations in Aggressive Youth with Bipolar Disorders, K Saxena, L Tamm, A Walley, A Simmons, N Rollins, J Chia, JC Soares, GJ Emslie, X Fan & H Huang, Journal of Child and Adolescent Psychopharmacology, 22, 112-9 (2012).
  • A second generation MRI contrast agent for imaging zinc ions in vivo, LM De León-Rodríguez, AJM Lubag, JA López, G Andreu-De-Riquer, JC Alvarado-Monzón & AD Sherry, MedChemComm, 4, 480-483 (2012).
  • Advantages of paramagnetic chemical exchange saturation transfer (CEST) complexes having slow to intermediate water exchange properties as responsive MRI agents, TC Soesbe, Y Wu & AD Sherry, NMR Biomed. Oct 11 (2012). doi: 10.1002/nbm.2874. [Epub ahead of print].
  • Amphiphilic EuDOTA-Tetraamide Complexes Form Micelles with Enhanced CEST Sensitivity, OM Evbuomwan, GE Kiefer & AD Sherry, European Journal of Inorganic Chemistry, 12, 2126-2134 (2012).
  • Analysis of tumor metabolism reveals mitochondrial glucose oxidation in genetically diverse human glioblastomas in the mouse brain in vivo, I Marin-Valencia, C Yang, T Mashimo, S Cho, H Baek, X-L Yang, KN Rajagopalan, M Maddie, V Vemireddy, Z Zhao, L Cai, L Good, BP Tu, KJ Hatanpaa, BE Mickey, JM Matés, JM Pascual, EA Maher, CR Malloy, RJ DeBerardinis & RM Bachoo, Cell Metabolism, 15, 827-837 (2012).
  • CEST: From basic principles to applications, challenges and opportunities, E Vinogradov, AD Sherry & RE Lenkinski, J Magn Reson., 2012 Dec 6. pii: S1090-7807(12)00368-0. doi: 10.1016/j.jmr.2012.11.024. [Epub ahead of print].
  • Comparison of Kinetic Models for Analysis of Pyruvate-to-Lactate Exchange by Hyperpolarized 13C NMR, C Harrison, C Yang, A Jindal, RJ DeBerardinis, MA Hooshyar, M Merritt, AD Sherry & CR Malloy, NMR in Biomedicine, 25, 1286-94 (2012).
  • Compressive Sensing Could Accelerate 1H MR Metabolic Imaging in the Clinic, S Geethanath, H Baek, SK Ganji, Y Ding, RD Sims, C Choi, MA Lewis & VD Kodibagkar, Radiology, 262:985-94 (2012).
  • Dissolution DNP-NMR spectroscopy using galvinoxyl as a polarizing agent, LL Lumata, ME Merritt, CR Malloy, AD Sherry, J van Tol, L Song & Z Kovacs, J of Magnetic Resonance, 227C, 14-19 (2012).
  • Dynamic monitoring of carnitine and acetylcarnitine in the trimethylamine signal after exercise in human skeletal muscle by 7T (1) H-MRS. J Ren, S Lakoski, RG Haller, AD Sherry & CR Malloy, Magn Reson Med, 69,7-17 (2012).
  • Elevated TCA cycle function in the pathology of diet-induced hepatic insulin resistance and fatty liver. S Satapati, NE Sunny, B Kucejova, X Fu, TT He, A Méndez-Lucas, JM Shelton, JC Perales, JD Browning & SC Burgess. Journal of Lipid Research, 53, 1080-1092 (2012).
  • Europium(III) DOTA-tetraamide complexes as redox active MRI sensors, J Ratnakar, S Viswanathan, Z Kovács, A Jindal, K Green & AD Sherry , JACS, 134, 5798-800 (2012).
  • Fast Dissolution Dynamic Nuclear Polarization NMR of 13C-Enriched 89Y-DOTA Complex: Experimental and Theoretical Considerations, L Lumata, M Merritt, C Malloy, AD Sherry & Z Kovacs, Applied Magnetic Resonance, 43, 69-79 (2012).
  • Glucose metabolism via the pentose phosphate pathway, glycolysis and Krebs cycle in an orthotopic mouse model of human brain tumors. I Marin-Valencia, SK Cho, D Rakheja, KJ Hatanpaa, P Kapur, T Mashimo, A Jindal, V Vemireddy, LB Good, J Raisanen, X Sun, B Mickey, C Choi, M Takahashi, O Togao, JM Pascual, RJ Deberardinis, EA Maher, CR Malloy & RM Bachoo, Cancer Research, 2012 Mar 1. doi: 10.1002/nbm.2787. [Epub ahead of print], accepted.
  • Impact of Gd 3+ on DNP of [1- 13C]pyruvate doped with trityl OX063, BDPA, or 4-oxo-TEMPO, L Lumata, ME Merritt, CR Malloy, AD Sherry & Z Kovacs, Journal of Physical Chemistry A, 116, 5129-5138 (2012).
  • In vivo determination of human breast fat composition by (1) H magnetic resonance spectroscopy at 7 T, IE Dimitrov, D Douglas, J Ren, NB Smith, AG. Webb, AD Sherry & CR Malloy, Mag Reson Med, 67:20-6 (2012).
  • Keyhole chemical exchange saturation transfer, G Varma, RE Lenkinski & E Vinogradov, Magn Reson Med. 2012 Jan 13. doi: 10.1002/mrm.23310. [Epub ahead of print].
  • Liver-Specific PGC-1beta Deficiency Leads to Impaired Mitochondrial Function and Lipogenic Response to Fasting-Refeeding, KT Chambers, Z Chen, PA Crawford, X Fu, SC Burgess, L Lai, TC Leone, DP Kelly & BN Finck, PLoS One. 7, e52645 (2012).
  • Metabolic manifestations of insulin deficiency do not occur without glucagon action, Y Lee, ED Berglund, MY Wang, X Fu, X Yu, MJ Charron, SC Burgess & RH Unger, Proc Natl Acad Sci U S A, 109, 14972-6 (2012).
  • Metabolism of [U-(13) C]glucose in human brain tumors in vivo , EA Maher, I Marin-Valencia, RM Bachoo, T Mashimo, J Raisanen, K Hatanpaa, A Jindal, FM Jeffrey, C Choi, C Madden, D Mathews, JM Pascual, BE Mickey, CR Malloy & RJ DeBerardinis. NMR in Biomedicine, (2012) doi: 10.1002/nbm.2794. [Epub ahead of print].
  • Nanoparticle-based PARACEST agents: the quenching effect of silica nanoparticles on the CEST signal from surface-conjugated chelates, OM Evbuomwan, ME Merritt, GE Kiefer & AD Sherry, Contrast Media Mol Imaging, 7, 19-25 (2012).
  • On improving the speed and reliability of T2-Relaxation-Under-Spin-Tagging (TRUST) MRI, F Xu, J Uh, P Liu & H Lu, Magnetic Resonance in Medicine, 68 :198-204 (2012).
  • pCEST: Positive contrast using Chemical Exchange Saturation Transfer, E Vinogradov, TC Soesbe, JA Balschi, AD Sherry & RE Lenkinski, J .Magn. Reson., 215, 64-73 (2012).
  • Phase-adjusted echo time (PATE)-averaging (1) H MRS: application for improved glutamine quantification at 2.89 T, AP Prescot, T Richards, SR Dager, C Choi & PF Renshaw, NMR Biomed., (2012) Mar 12. [Epub ahead of print].
  • Positron emission tomography of copper metabolism in the Atp7b -/- knock-out mouse model of wilson’s disease, F Peng, S Lutsenko, X Sun & O Muzik, Mol Imaging Biol. 14: 70-8 (2012).
  • Reply to: Intramyocellular lipids vs. intramyocellular triglycerides, J Ren , AD Sherry & CR Malloy, Magn Reson Med, 67, 299 (2012).
  • Synthesis and characterization of a hypoxia-sensitive MRI probe, F Rojas-Quijano, G Tircso, E Tircsone Benyo, Z Baranyai, H Hoang, F Kalman, P Gulaka, V Kodibagkar, S Aime, Z Kovács, AD Sherry, Chemistry, 18, 9669-9676 (2012).
  • The efficiency of DPPH as a polarising agent for DNP-NMR spectroscopy, L Lumata, M Merritt, C Khemtong, SJ Ratnakar, J van Tol, L Yu, L Song & Z Kovacs, RSC Adv. 2, 12812-12817 (2012).
  • Use of 2H2O for estimating rates of gluconeogenesis: Determination and correction of error due to transaldolase exchange, JD Browning & SC Burgess, 303, E1304-12 (2012). Epub 2012 Oct 2.
  • Evidence for transaldolase activity in the isolated heart supplied with [U-13C3]glycerol, ES Jin, AD Sherry & CR Malloy, Journal of Biological Chemistry, 288, 2914 - 2922 (2013).
  • Hepatic glucose production pathways after three days of a high-fat diet, ES Jin, SA Beddow, CR Malloy & VT Samuel, Metabolism, 62, 152-622 (2013).
  • The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging edited by Merbach, Toth and Helm, Chapter 5 entitled Stability and Toxicity of Contrast Agents, E Brücher, G Tircsó, Z Baranyai, Z Kovács & AD Sherry, Wiley VCH (2013).
  • Heptanoate as a neural fuel: energetic and neurotransmitter precursors in normal and glucose transporter I-deficient (G1D) brain, I Marin-Valencia, LB Good, Q Ma, CR Malloy & JM Pascual, J Cereb Blood Flow Metab., 33, 175-182 (2013).
  • Numerical analysis of correlations between the NMR chemical shifts of hyperpolarized 89Y complexes and their chemical structures, Y Xing, AK Jindal, P Zhao, Z Kovacs & AD Sherry, in preparation.
  • Selective Excitation for Enhanced Detection of pH and Flux in Hyperpolarized NMR Experiments, Crystal Harrison, Ashish Jindal, Charles Storey, M.A. Hooshyar, Matthew E. Merritt, A. Dean Sherry, and Craig R. Malloy, Magn. Reson. in preparation.
  • Introduction to 13C NMR for Isotopomer Analysis of the Citric Acid Cycle, CR Malloy, E Maher, I Marin-Valencia, B Mickey, RJ DeBerardinis & AD Sherry, in press.
  • Cortical metabolism in pyruvate dehydrogenase deficiency revealed by ex vivo multiplet 13C NMR of the adult mouse brain, Marin-Valencia I, Good LB, Ma Q, Malloy CR, Patel MS & Pascual JM, Neurochem Int. 2012 Aug 3. [Epub ahead of print]. In press.