Recent Publications from AIRC Staff and Collaborators

  • (31) P-MRS of healthy human brain: ATP synthesis, metabolite concentrations, pH, and T1 relaxation times, J Ren, AD Sherry & CR Malloy, NMR Biomed., 28, 1455-62 (2015). 
  • A pH-Responsive MRI Agent that Can Be Activated Beyond the Tissue Magnetization Transfer Window,  X Wang, Y W2, T Soesbe, J Yu, P Zhao, GE Kiefer& AD Sherry, Angew Chem Int Ed Engl., 54,8662-4 (2015).
  • A roadmap for interpreting 13C metabolite labeling patterns from cells, JM Buescher, MR Antoniewicz, LG Boros, SC Burgess, H Brunengraber, CB Clish, RJ DeBerardinis, O Feron, C Frezza, B Ghesquiere, E Gottlieb, K Hiller, RG Jones, JJ Kamphorst, RG Kibbey, AC Kimmelman, JW Locasale, SY Lunt, ODK Maddocks, C Malloy, CM Metallo, EJ Meuillet, J Munger, JD Nöh, K., Rabinowitz, M Ralser, U Sauer, G Stephanopoulos, J St-Pierre, DA Tennant, C Wittmann, MG Vander Heiden, A Vazquez, K Vousden, JD Young,  N Zamboni & SM Fendt, Current Opinion in Biotechnology, 34, 189-201 (2015).
  • A switched-mode breast coil for 7 tesla MRI using forced-current excitation. J Cui, J Bosshard, J Rispoli, I Dimitrov, S Cheshkov, M McDougall, C Malloy & Wright S.  IEEE Trans Biomed Eng., 62, 1777-83 (2015).
  • Basic MR Relaxation Mechanisms & Contrast Agent Design. LM De León-Rodríguez, AF Martins, MC Pinho MC, NM Rofsky & AD Sherry, J Magn Reson Imaging., 42, 545-65 (2015).
  • Conditions for 13C NMR detection of 2-hydroxyglutarate in tissue extracts from isocitrate dehydrogenase-mutated gliomas, K Pichumani, T Mashimo, HM Baek, J Ratnakar, B Mickey, RJ DeBerardinis, EA Maher, RM Bachoo, CR Malloy & Z Kovacs, Anal Biochem, 15; 481, 4-6 (2015).
  • Exchange kinetics by inversion transfer: Integrated analysis of the phosphorus metabolite kinetic exchanges in resting human skeletal muscle at 7 T, J Ren, B Yang, Sherry &  CR Malloy, Magn Reson Med, 73, 1359-69 (2015).
  • Hyperpolarized 13C NMR Detects Rapid Drug-induced Changes in Cardiac Metabolism,   C Khemtong, NR Carpenter, LL Lumata, ME Merritt, KX Moreno, Z Kovacs, CR Malloy & AD Sherry, Magn Reson Med, 74, 312 - 319 (2015).
  • Hyperpolarized (15)N-pyridine Derivatives as pH-Sensitive MRI Agents, W Jiang, L Lumata, W Chen, S Zhang, Z Kovacs, AD Sherry, & C Khemtong, Sci Rep., 5, 9104 (2015).
  • Influence of Liver Triglycerides on Suppression of Glucose Production by Insulin in Men, ES Jin, M Szuszkiewicz-Garcia, JD Browning, JD Baxter, N Abate & CR Malloy, Men. J Clin Endocrinol Metab., 100, 235 - 243 (2015).
  • Limitations of detection of anaplerosis and pyruvate cycling from metabolism of [1-(13)C] acetate. SC Burgess, ME Merritt, JG Jones, JD Browning, AD Sherry & CR Malloy, Nat Med., 21,108-9 (2015).
  • Molecular platform for design and synthesis of targeted dual-modality imaging probes, A Kumar A, S Zhang, G Hao, G Hassan, S Ramezani, K Sagiyama, ST Lo, M Takahashi, AD Sherry, OK Öz OK, Z Kovacs & X Sun, Bioconjug Chem., 26: 549-58 (2015).
  • Production of hyperpolarized 13CO2 from [1-13C]pyruvate in perfused liver does reflect total anaplerosis but is not a reliable biomarker of glucose production, KX Moreno, CL Moore, SC Burgess, AD Sherry, CR Malloy & ME Merritt, Metabolomics, 11, 1144 - 1156 (2015).
  • The ratio of acetate-to-glucose oxidation in astrocytes from a single (13) C NMR spectrum of cerebral cortex.  I Marin-Valencia, MA Hooshyar, K Pichumani, AD Sherry, & CR Malloy, J Neurochem., 132, 99-109 (2015). 
  • 1H MRS characterization of neurochemical profiles in orthotopic mouse models of human brain tumors.  Hulsey KM, Mashimo T, Banerjee A, Soesbe TC, Spence JS, Vemireddy V, Maher EA, Bachoo RM & Choi C,  NMR in Biomedicine, 28:108-115 (2015).
  • Development and performance of a 129-GHz dynamic nuclear polarizer in an ultra-wide bore superconducting magnet, LL Lumata, R Martin, AK Jindal, Z Kovacs, MS Conradi, ME Merritt, MAGMA, Apr;28, 195-205 (2015).
  • Hyperpolarized (13)C Magnetic Resonance and Its Use in Metabolic Assessment of Cultured Cells and Perfused Organs, L Lumata, C Yang, M Ragavan, N Carpenter, RJ DeBerardinis & ME Merritt, Methods in Enzymology, Methods Enzymol., 73-106 (2015).
  • Nuclear spin hyperpolarization of the solvent using signal amplification by reversible exchange (SABRE), KX Moreno, K Nasr, M Milne, AD Sherry & WJ Goux, Journal of Magnetic Resonance, 257 , 15 - 23 (2015).
  • In vivo 1H MRSI of glycine in brain tumors at 3T.  SK Ganji, EA Maher& C Choi. Magnetic Resonance in Medicine, 2015 Feb 4. doi: 10.1002/mrm.25588. [Epub ahead of print].
  • [68Ga]-HP-DO3A-nitroimidazole: a promising agent for PET detection of tumor hypoxia. Y Wu, G Hao, S Ramezani, D Saha, D Zhao, X Sun & AD Sherry, Contrast Media Mol Imaging. 2015 Jun 29. doi: 10.1002/cmmi.1649. [Epub ahead of print].
  • A simple approach to evaluate the kinetic rate constant for ATP synthesis in resting human skeletal muscle at 7 T, J Ren, AD Sherry & CR Malloy, NMR in Biomedicine, 2015 May 6. doi: 10.1002/nbm.3310. [Epub ahead of print].
  • Numerical Analysis of Correlations between the NMR Chemical Shifts of Hyperpolarized 89Y Complexes and their Chemical Structures, Y Xing, AK Jindal, P Zhao, Z Kovacs & AD Sherry, in preparation.