Recent Publications from AIRC Staff and Collaborators

  • A general chemical shift decomposition method for hyperpolarized 13 C metabolite magnetic, JX Wang, ME Merritt, D Sherry & CR Malloy, Magn Reson Chem., 54, 665-73 (2016).
  • Accelerated chemical shift imaging of hyperpolarized (13) C metabolites, JX Wang, ME Merritt, AD Sherry & CR Malloy, Magn Reson Med., 2016 Oct;76(4):1033-8. doi: 10.1002/mrm.26286. Epub 2016 Jul 4.
  • An Oral Load of [13C3]Glycerol and Blood NMR Analysis Detect Fatty Acid Esterification, Pentose Phosphate Pathway and Glycerol Metabolism through the Tricarboxylic Acid Cycle in Human Liver, ES Jin, ADS Sherry & CR Malloy, J Biol Chem., 291, 19031-41 (2016).
  • Assessing Cardiac Metabolism: A Scientific Statement From the American Heart Association, H Taegtmeyer, ME Young , GD Lopaschuk, ED Abel, H Brunengraber, V Darley-Usmar, C Des Rosiers , R Gerszten, JF Glatz, JL Griffin, RJ Gropler, HG Holzhuetter, JR Kizer, ED Lewandowski, CR Malloy, S Neubauer, LR Peterson, MA Portman, FA Recchia, JE Van Eyk & TJWang TJ, Circ Res., 118,1659-701 (2016).
  • Band Inversion Amplifies 31P-31P Nuclear Overhauser Effects: Relaxation Mechanism and Dynamic Behavior of ATP in the Human Brain by 31P MRS at 7T, J Ren, AD Sherry & CR Malloy, Mag. Res in Med., 2016 Apr 8. doi: 10.1002/mrm.26236. [Epub ahead of print].
  • Efficient 31P Band Inversion Transfer Approach for Measuring Creatine Kinase Activity, ATP Synthesis and Molecular Dynamics in the Human Brain at 7T, J Ren, AD Sherry & CR Malloy, Magn Reson Med. 2016 Nov 20. doi: 10.1002/mrm.26560. [Epub ahead of print].
  • Hepatic Arterial Infusion of Low-Density Lipoprotein Docosahexaenoic Acid Nanoparticles Selectively Disrupts Redox Balance in Hepatoma Cells and Reduces Growth of Orthotopic Liver Tumors in Rats,X Wen, L Reynolds, RS Mulik, SY Kim, T Van Treuren, LH Nguyen, H Zhu, IR Corbin, Gastroenterology, 150, 488-98 (2016).
  • Hepatic Gluconeogenesis Influences 13C Enrichment in Lactate in Human Brain Tumors During Metabolism of [1,2-13C]acetate, K Pichumani, T Mashimo, V Vemireddy, Z Kovacs, J Ratnakar, B Mickey, CR Malloy, DeBerardinis, RM Bachoo , EA Maher, Neurochem Int., 97, 133-6 (2016).
  • Impact of Ho(3+)-doping on (13)C Dynamic Nuclear Polarization Using Trityl OX063 Free Radical, A Kiswandhi , P Niedbalski, C Parish, P Kaur, A Martins, L Fidelino, C Khemtong, L Song, AD Sherry & L Lumata, Phys Chem Chem Phys. 18, 21351-9 (2016).
  • Integration of 13C Isotopomer Methods and Hyperpolarization Provides a Comprehensive Picture of Metabolism, AD Sherry & CR Malloy, eMagRes, 2016, 1, 885–900. DOI 10.1002/9780470034590 .emrstm1468. (2016).
  • "Investigation into the distinct subcellular effects of docosahexaenoic acid loaded low-density lipoprotein nanoparticles in normal and malignant murine liver cells, LR Moss, RS Mulik, T Van Treuren, SY Kim & IR Corbin, Biochim Biophys Acta., 1860, 2363-76 (2016).
  • Metabolic Heterogeneity in Human Lung Tumors, CT Hensley, B Faubert, Q Yuan, N Lev-Cohain, E Jin, J Kim, L Jiang, B Ko, R Skelton, L Loudat, M Wodzak, C Klimko, E McMillan, Y Butt, M Ni, D Oliver, J Torrealba, CR Malloy, K Kernstine, RE Lenkinski & RJ DeBerardinis, Cell, 164, 681-94 (2016).
  • Metabolism of hyperpolarized [1-13 C]pyruvate through alternate pathways in rat liver, ES Jin, KX Moreno, JX Wang, L Fidelino, ME Merritt, AD Sherry & CR Malloy, NMR Biomed., 29, 66-74 (2016).
  • Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver, S Satapati, B Kucejova, JA Duarte, JA Fletcher, L Reynolds, NE Sunny, T He, L Nair, K Livingston, X Fu, ME Merritt, AD Sherry, CR Malloy, JM Shelton, J Lambert, EJ Parks, I Corbin, Magnuson MA, JD Browning & SC Burgess, J Clin Invest., 126, 1605 (2016).
  • Multiband Spectral-Spatial RF Excitation for Hyperpolarized [2 13C]Dihydroxyacetone 13C-MR Metabolism Studies. Magnetic resonance in medicine, I Marco-Rius, P Cao, C von Morze, M Merritt, KX Moreno, GY Chang, MA Ohliger, D Pearce, J Kurhanewicz, PE Larson & DB Vigneron, Magn Reson Med., 2016 Mar 28. doi: 10.1002/mrm.26226. [Epub ahead of print].
  • Novel application of complimentary imaging techniques to examine in vivo glucose metabolism in the kidney, T Hato, AN Friedman, HE Mang , Z Plotkin, S Dube, GD Hutchins, PR Territo, BP McCarthy, AA Riley, K Pichumani, CR Malloy, RA Harris, PC Dagher & TA Sutton, Am J Physiol Renal Physiol. (2016) Jan 13:ajprenal.00535.2015. doi: 10.1152/ajprenal.00535.2015. [Epub ahead of print].
  • Oxidative Conversion of a Europium(II)-Based T1 Agent to a Europium(III)-Based paraCEST Agent that can be Detected In Vivo by Magnetic Resonance Imaging, AM Funk, V Clavijo Jordan, AD Sherry, SJ Ratnakar & Z Kovacs, Angew Chem Int Ed Engl., 55, 5024-7 (2016).
  • Phosphatidylserine-targeted liposome for enhanced glioma-selective imaging. L Zhang, AA Habib, D Zhao, Oncotarget, 2016 May 25. doi: 10.18632/oncotarget.9584. [Epub ahead of print].
  • The Relationship between NMR Chemical Shifts of Thermally Polarized and Hyperpolarized 89 Y Complexes and Their Solution Structures, Y Xing, AK Jindal, M Regueiro-Figueroa, M Le Fur, N Kervarec, P Zhao, Z Kovacs, L Valencia, P Pérez-Lourido, R Tripier, D Esteban-Gómez, C Platas-Iglesias & AD Sherry, Chemistry. 2016 Oct 10. doi: 10.1002/chem.201602901.
  • A Belfatto, DA White, RP Mason, Z Zhang, S Stojadinovic, G Baroni & P Cerveri, Tumor radio-sensitivity assessment by means of volume data and magnetic resonance indices measured on prostate tumor bearing rats. Med Phys., 43,1275 (2016).
  • Unexpected Changes in the Population of Coordination Isomers for the Lanthanide Ion Complexes of DOTMA-Tetraglycinate, C Kumas, WS Fernando, P Zhao, M Regueiro-Figueroa, GE Kiefer, AF Martins, C Platas-Iglesias & AD Sherry AD, Inorg Chem. 2016 Sep 7. [Epub ahead of print] PubMed PMID: 27603690.
  • CM Walker, M Merritt, JX Wang & JA Bankson , Use of a Multi-compartment Dynamic Single Enzyme Phantom for Studies of Hyperpolarized Magnetic Resonance Agents, J Vis Exp., Apr 15;(110). (2016)
  • Zinc-sensitive MRI contrast agent detects differential release of Zn(II) ions from the healthy vs. malignant mouse prostate, MV Clavijo Jordan, ST Lo, S Chen, C Preihs, S Chirayil, S Zhang, P Kapur, WH Li, LM De Leon-Rodriguez, AJ Lubag, NM Rofsky & AD Sherry AD, Proc Natl Acad Sci U S A, 113, E5464-71 (2016).