Recent Publications from AIRC Staff and Collaborators

  • A Comprehensive Analysis of Myocardial Substrate Preference Emphasizes the Need For a Synchronized Fluxomic/Metabolomic Research Design, M Ragavan, A Kirpich, X2 Fu, SC Burgess, LM McIntyre & ME Merritt, Am J Physiol Heart Circ Physiol., 312, H1215-H1223 (2017).
  • An Adjustable-length Dipole Using Forced-Current Excitation for 7T MR, J Cui, IE Dimitrov, S Cheshkov, M Gu, CR Malloy & SM Wright, Transactions on Biomedical Engineering, in Press.
  • Automated modification and fusion of voxel models to construct body phantoms with heterogeneous breast tissue: Application to MRI simulations, JV Rispoli, SM Wright, CR Malloy & MP McDougall, J Biomed Graph Comput., 7, 1-7 (2017).
  • Cancer Metabolism and Tumor Heterogeneity: Imaging Perspectives Using MR Imaging and Spectroscopy, L Gigin, K Keshari & JM Park, Contrast Media Mol Imaging, 6053879l (2017).
  • Detection of 2-hydroxyglutarate in brain tumors by triple-refocusing MR spectroscopy at 3T in vivo, Z An, SK Ganji, V Tiwari, MC Pinho, T Patel, S Barnett, E Pan, BE Mickey, EA Maher & C Choi, Magn Reson Med., 78, 40-48 (2017).
  • Effects of visceral adiposity on glycerol pathways in gluconeogenesis, IJ Neeland, C Hughes, CR Ayers, CR Malloy & ES Jin, Metabolism, 67, 80-89 (2017).
  • Electrochemical investigation of the Eu3+/2+ redox couple in complexes with variable numbers of glycinamide and acetate pendant arms, J Ratnakar, M Brunett, B Adebesin, A Funk, Z Kovacs, AD Sherry, LA Ekanger, MJ Allen & K Green, EurJIC, in process 11/22/17.
  • Enantiomeric recognition of D- and L-lactate by CEST with the aid of a paramagnetic shift reagent, L Zhang, AF Martins, P Zhao, M Tieu, D Esteban-Gomez, GT McCandless, C Platas-Iglesias & Sherry AD, J Am Chem Soc., 2017 Oct 30. doi: 10.1021/jacs.7b08292. [Epub ahead of print].
  • Hyperpolarized Sodium [1-13C]-Glycerate as a Probe for Assessing Glycolysis in Vivo, JM Park, M Wu, K Datta, S-C Liu, A Castillo, He Lough, DM Spielman & KL Billingsley, J Am Chem Soc., 139, 6629-6634 (2017).
  • Hyperpolarized δ-[1-13 C]gluconolactone as a probe of the pentose phosphate pathway, KX Moreno, CE Harrison, ME Merritt, Z Kovacs, CR Malloy & AD Sherry,  NMR Biomed.,  30, e3713 (2017).
  • Imaging Extracellular Lactate In Vitro and In Vivo Using CEST MRI and a Paramagnetic Shift Reagent, L Zhang, AF Martins, Y Mai, P Zhao, AM Funk, MV Clavijo Jordan, S Zhang, W Chen, Y Wu & AD Sherry, Chemistry,23, 1752-1756  (2017).
  • In Vivo Assessment of Intracellular Redox State in Rat Liver Using Hyperpolarized [1-13C]Alanine, JM Park, C Khemtong,  SC Liu, RE Hurd & DM Spielman, Magn Reson Med., May;77, 1741-1748 (2017).
  • Influence of Dy3+ and Tb3+ doping on 13C dynamic nuclear polarization, P Niedbalski, C Parish, A Kiswandhi, L Fidelino, C Khemtong, Z Hayati, L Song, A Martins, AD Sherry & L Lumata, J Chem Phys., 7, 146, 014303 (2017).
  • Intramyocellular lipid excess in the mitochondrial disorder MELAS: MRS determination at 7T, S Golla, J Ren, CR Malloy, JM Pascual, Neurol Genet, 3, e160 (2017).
  • Lactate Metabolism in Human Lung Tumors, B Faubert, KY Li, L Cai, CT Hensley, J Kim, LG Zacharias, C Yang, QN Do, S Doucette, D Burguete, H Li, G Huet, Q Yuan, T Wigal, Y Butt, M Ni, J Torrealba, D Oliver, RE Lenkinski, CR Malloy, JW Wachsmann, JD Young, K Kernstine & RJ DeBerardinis, Cell, 171, 358-371.e9 (2017).
  • Lanthanide-based T2ex and CEST complexes provide new insights into the design of pH sensitive MRI agents, L Zhang, AF Martins, P Zhao, Y Wu, G Tircso & AD Sherry, Angew Chem Int Ed Engl., 2017 Oct 11; PubMed PMID: 29024242.
  • Measurement of 13C Turnover into Glutamate and Glutamine Pools in Brain Tumor Patients, K Pichumani, T Mashimo, V Vemireddy, OB Ijare, BE Mickey, CR Malloy, I Marin-Valencia, DS Baskin, RM Bachoo & EA Maher, FEBS Letter, ( 2017) ep 30. doi: 10.1002/1873-3468.12867. [Epub ahead of print].
  • Measurement of glycine in healthy and tumorous brain by triple-refocusing MRS at 3 T in vivo, V Tiwari, Z An, SK Ganji, J Baxter, TR Patel, E Pan, BE Mickey, EA Maher, MC Pinho MC & C Choi, NMR Biomed., 30 (9), (2107).
  • Measuring glucose cerebral metabolism in the healthy mouse using hyperpolarized 13C magnetic resonance, M Mishkovsky, B Anderson, M Karlsson, MH Lerche, AD Sherry, R Gruetter, Z Kovacs & A Comment, Sci Rep.,7, 11719 (2017).
  • Monitoring acute metabolic changes in the liver and kidneys induced by fructose and glucose using hyperpolarized [2-13 C]dihydroxyacetone, I Marco-Rius, C von Morze, R Sriram, P Cao, GY Chang, E Milshteyn, RA Bok, MA Ohliger, D Pearce, J Kurhanewicz, PE Larson, DB Vigneron & MM Merritt, Magnetic Resonance in Medicine, 77(1):65-73 (2017).
  • On-bead combinatorial synthesis and imaging of europium(III)-based paraCEST agents aids in identification of chemical features that enhance CEST sensitivity, J Singh, V Rustagi, S Zhang, AD Sherry & DG Udugamasooriya, Magn Reson Chem., 55, 747-753 (2017).
  • Oxidation of [U-13 C]glucose in the human brain at 7T under steady state conditions, S Cheshkov, E Dimitrov, V Jakkamsetti, L Good, D Kelly, K Rajasekaran, R DeBerardinis, JM Pascual, AD Sherry & CR Malloy, Magn Reson Med., 2017 Jan 23. doi: 10.1002/mrm.26603. [Epub ahead of print].
  • Oxidation of [U-13C]glucose in the Human Brain at 7T under Steady State Conditions, S Cheshkov, IE Dimitrov, V Jakkamsetti, L Good, D Kelly, K Rajasekaran, RJ DeBerardinis, JM Pascual, AD Sherry & CR Malloy, Magn Reson Med, 78, 2065-2071 (2017).
  • Protonation of carboxyl groups in EuDOTA-tetraamide complexes results in catalytic prototropic exchange and quenching of the CEST signal, L Zhang, OM Evbuomwan, M Tieu, P Zhao, AF Martins & AD Sherry, Philos Trans A Math Phys Eng Sci., 375 (2107).
  • Real-time in vivo detection of H2O2 using hyperpolarized 13C-thiourea, A Wibowo, JM Park, Shie-C Liu, C Khosla & DM Spielman, ACS Chem. Biol., 2017 Jun 5. doi: 10.1021/acschembio.7b00130. [Epub ahead of print], (2017).
  • The rate of lactate production from glucose in hearts is not altered by per-deuteration of glucose, AM Funk, BL Anderson, X Wen, T Hever, C Khemtong, Z Kovacs, AD Sherry & CR Malloy, J Magn Reson., 284, 86-93 (2017).
  • Transition Metal Doping Reveals Link Between Electron T1 Reduction and 13C Dynamic Nuclear Polarization Efficiency, P Niedbalski, CR Parish, Q Wang, Z Hayati, L Song, AF Martins, AD Sherry & LL Lumata, J Phys Chem A., 2017 Nov 10. doi: 10.1021/acs.jpca.7b09448. [Epub ahead of print].
  • Tumor physiological changes during hypofractionated stereotactic body radiation therapy assessed using multi-parametric magnetic resonance imaging; H Zhou, Z Zhang, R Denney, J Williams, J Gerberich, S Stojadinovic, D Saha, JM Shelton & Mason RP1, Oncotarget, 8, 37464-37477 (2017).