Recent Publications from AIRC Staff and Collaborators

  • Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver, S Satapati, B Kucejova, JA Duarte, JA Fletcher, L Reynolds, NE Sunny, T He, L Nair, K Livingston, X Fu, ME Merritt, AD Sherry, CR Malloy, JM Shelton, J Lambert, EJ Parks, I Corbin, Magnuson MA, JD Browning & SC Burgess, J Clin Invest., 126, 1605 (2016).
  • Oxidative Conversion of a Europium(II)-Based T1 Agent to a Europium(III)-Based paraCEST Agent that can be Detected In Vivo by Magnetic Resonance Imaging, AM Funk, V Clavijo Jordan, AD Sherry, SJ Ratnakar & Z Kovacs, Angew Chem Int Ed Engl., 55, 5024-7 (2016).
  • Tumor radio-sensitivity assessment by means of volume data and magnetic resonance indices measured on prostate tumor bearing rats, A Belfatto, DA White, RP Mason, Z Zhang, S Stojadinovic, G Baroni & P Cerveri, Med Phys., 43,1275 (2016).
  • Unexpected Changes in the Population of Coordination Isomers for the Lanthanide Ion Complexes of DOTMA-Tetraglycinate, C Kumas, WS Fernando, P Zhao, M Regueiro-Figueroa, GE Kiefer, AF Martins, C Platas-Iglesias & AD Sherry AD, Inorg Chem., 2016 Sep 7. [Epub ahead of print].
  • Use of a Multi-compartment Dynamic Single Enzyme Phantom for Studies of Hyperpolarized Magnetic Resonance Agents, CM Walker, M Merritt, JX Wang & JA Bankson , J Vis Exp., 110; Apr 15 (2016).
  • Zinc-sensitive MRI contrast agent detects differential release of Zn(II) ions from the healthy vs. malignant mouse prostate, MV Clavijo Jordan, ST Lo, S Chen, C Preihs, S Chirayil, S Zhang, P Kapur, WH Li, LM De Leon-Rodriguez, AJ Lubag, NM Rofsky & AD Sherry AD, Proc Natl Acad Sci U S A, 113, E5464-71 (2016).
  • Prospective Longitudinal Analysis of 2-Hydroxyglutarate Magnetic Resonance Spectroscopy Identifies Broad Clinical Utility for the Management of Patients With IDH-Mutant Glioma, C Changho, JM Raisanen, SK Ganji, S Zhang, SS McNeil, Z An, A Madan, K J Hatanpaa, V Vemireddy, CA Sheppard, D Oliver, KM Hulsey, V Tiwari, T Mashimo, J Battiste, S Barnett, CJ Madden, TR Patel, E Pan, CR Malloy, BE Mickey, RM Bachoo & EA Maher, J of Oncology, Vol 34, NUM33, Nov 20 (2016).
  • Impact of Ho(3+)-doping on (13)C Dynamic Nuclear Polarization Using Trityl OX063 Free Radical, A Kiswandhi , P Niedbalski, C Parish, P Kaur, A Martins, L Fidelino, C Khemtong, L Song, AD Sherry & L Lumata, Phys Chem Chem Phys, 18, 21351-9 (2016).
  • The Relationship between NMR Chemical Shifts of Thermally Polarized and Hyperpolarized 89 Y Complexes and Their Solution Structures, Y Xing, AK Jindal, M Regueiro-Figueroa, M Le Fur, N Kervarec, P Zhao, Z Kovacs, L Valencia, P Pérez-Lourido, R Tripier, D Esteban-Gómez, C Platas-Iglesias & AD Sherry, Chemistry, 22, 16657-16667 (2016).
  • Hepatic Arterial Infusion of Low-Density Lipoprotein Docosahexaenoic Acid Nanoparticles Selectively Disrupts Redox Balance in Hepatoma Cells and Reduces Growth of Orthotopic Liver Tumors in Rats,X Wen, L Reynolds, RS Mulik, SY Kim, T Van Treuren, LH Nguyen, H Zhu, IR Corbin, Gastroenterology, 150, 488-98 (2016).
  • Phosphatidylserine-targeted liposome for enhanced glioma-selective imaging. L Zhang, AA Habib, D Zhao,Oncotarget, 7, 38693-38706 (2016).
  • "Prospective Longitudinal Analysis of 2-Hydroxyglutarate Magnetic Resonance Spectroscopy Identifies Broad Clinical Utility for the Management of Patients With IDH-Mutant Glioma, Changho Choi, ….Elizabeth A. Maher, J of Clinical Oncology, V 34, 33, Nov 20 (2016).
  • Multiband Spectral-Spatial RF Excitation for Hyperpolarized [2 13C]Dihydroxyacetone 13C-MR Metabolism Studies. Magnetic resonance in medicine, I Marco-Rius, P Cao, C von Morze, M Merritt, KX Moreno, GY Chang, MA Ohliger, D Pearce, J Kurhanewicz, PE Larson & DB Vigneron, Magn Reson Med, Mar 28. (2016). [Epub ahead of print]
  • Monitoring acute metabolic changes in the liver and kidneys induced by fructose and glucose using hyperpolarized [2-13 C]dihydroxyacetone, I Marco-Rius, C von Morze, R Sriram, P Cao, GY Chang, E Milshteyn, RA Bok, MA Ohliger, D Pearce, J Kurhanewicz, PE Larson, DB Vigneron & MM Merritt, Magn Reson Med, Nov 12 (2016). Issue online: 27 December 2016.
  • Integration of 13C Isotopomer Methods and Hyperpolarization Provides a Comprehensive Picture of Metabolism, AD Sherry & CR Malloy, eMagRes, 2016, 1, 885–900 (2016).
  • "Effects of visceral adiposity on glycerol pathways in gluconeogenesis, IJ Neeland, C Hughes, CR Ayers, CR Malloy & ES Jin, Metabolism, 67, 80-89 (2017).
  • Influence of Dy3+ and Tb3+ doping on 13C dynamic nuclear polarization, P Niedbalski, C Parish, A Kiswandhi, L Fidelino, C Khemtong, Z Hayati, L Song, A Martins, AD Sherry & L Lumata, J Chem Phy, 7, 146, 014303 (2017).
  • Band Inversion Amplifies 31P-31P Nuclear Overhauser Effects: Relaxation Mechanism and Dynamic Behavior of ATP in the Human Brain by 31P MRS at 7T, J Ren, AD Sherry & CR Malloy, Magn Reson Med, 77, 1409-1418 (2017).
  • Real-time in vivo detection of H2O2 using hyperpolarized 13C-thiourea, A Wibowo, JM Park, Shie-C Liu, C Khosla & DM Spielman, ACS Chem. Biol, Publication Date (Web): 28 Apr (2017).
  • Oxidation of [U-13C]glucose in the Human Brain at 7T under Steady State Conditions, S Cheshkov, IE Dimitrov, V Jakkamsetti, L Good, D Kelly, K Rajasekaran, RJ DeBerardinis, JM Pascual, AD Sherry & CR Malloy, Magn Reson Med, Jan 23 (2017).  
  • Hyperpolarized Sodium [1-13C]-Glycerate as a Probe for Assessing Glycolysis in Vivo, JM Park, M Wu, K Datta, S-C Liu, A Castillo, He Lough, DM Spielman & KL Billingsley, May 4, (2017).
  • Oxidation of [U-13 C]glucose in the human brain at 7T under steady state conditions, S Cheshkov, E Dimitrov, V Jakkamsetti, L Good, D Kelly, K Rajasekaran, R DeBerardinis, JM Pascual, AD Sherry & CR Malloy, Magn Reson Med, Jan 23 (2017). [Epub ahead of print].
  • Hyperpolarized δ-[1- 13 C]gluconolactone as a probe of the pentose phosphate pathway, KX Moreno, CE Harrison, ME Merritt, Z Kovacs, CR Malloy & AD Sherry, NMR Biomed, Mar 8 (2017) [Epub ahead of print].
  • On-bead combinatorial synthesis and imaging of europium(III)-based paraCEST agents aids in identification of chemical features that enhance CEST sensitivity, J Singh, V Rustagi, S Zhang, AD Sherry & DG Udugamasooriya DG, Magn Reson Chem, Feb 21 (2017) . [Epub ahead of print].
  • A Comprehensive Analysis of Myocardial Substrate Preference Emphasizes the Need For a Synchronized Fluxomic/Metabolomic Research Design, M Ragavan, A Kirpich, X2 Fu, SC Burgess, LM McIntyre & ME Merritt, Am J Physiol Heart Circ Physiol, Apr 1, (2017). [Epub ahead of print].
  • In Vivo Assessment of Intracellular Redox State in Rat Liver Using Hyperpolarized [1-13C]Alanine, JM Park, C Khemtong, SC Liu, RE Hurd & DM Spielman. Magn Reson Med, Mar 5 (2017). Issue online: 18 April (2017).
  • An Adjustable-length Dipole Using Forced-Current Excitation for 7T MR, J Cui, IE Dimitrov, S Cheshkov, M Gu, CR Malloy & SM Wright, Trans on Biomedical Engineering, in Press.