AIRC Faculty Patents

Hyperpolarized 89-ytrrium and methods relating thereto

 Z Kovacs, ME Merritt, and AD Sherry
U.S. Patent App. No. 61/104,487 (2008).

Measurement of Gluconeogenesis and Intermediary Metabolism Using Stable Isotopes

J Jones, AD Sherry and CR Malloy
US Patent 7,256,047, Issued: Aug 14, 2007.

Bifunctional polyazamacrocyclic chelating agents

Z Kovacs, GE Kiefer, C Bensimon, AD Sherry, and G Tirsco
PCT Int. Appl, WO 2007104135 (2007).

Bifunctional Polyazamacrocyclic Chelating Agents

Z Kovacs, GE Kiefer, C Bensimon, AD Sherry and G Tircso
PCT Int. Appl.  WO104135 (2007).

Paramagnetic Metal ion-based Macrocyclic Magnetization Transfer (MT) Contrast Agents and Method of Use

AD Sherry, S Zhang and K Wu
U.S. Patent 6,875,419, Filed: Nov. 20, 2001, Issued: April 5, 2005.

Improved Process for Making a Chelating Agent for Labeling Biomolecules using Preformed Active Esters

Z Kovacs, DS Mudigonda and AD Sherry
U.S. Patent 6,838,557, Filed: Nov 2002, Issued: Jan 4, 2005.

Preformed Carboxylated Active Ester for Labeling Biomolecules

Z Kovacs, DS Mudigonda and AD Sherry
U.S. Patent 6,852,854, Filed Nov 2002, Issued: Feb 8, 2005.

Process for making a chelating agent for labeling biomolecules using preformed active esters

Z Kovacs, DS Mudigonda and AD Sherry
U.S. Patent 6,838,557, Filed Nov. 2002, Issued: Jan 4, 2005.

Preparation of Cyclic Tertiary Amine Chelating Agents for Labeling Biomolecule Using Preformed Active Esters

Z Kovacs, DS Mudigonda and AD Sherry
US 6838557 (2005).

pH Sensitive MRI Contrast Agents

AD Sherry, S Zhang and K Wu
U.S. Patent 6,746,662. Filed: Feb. 9, 2000; Issued Jun. 8, 2004.

Lactate Dehydrogenase as a Novel Target and Reagent for Diabetes Therapy

C Newgard, M Jensen, AD Sherry and S Burgess
UTSD: 0984. Filed: January 21, 2003.

Selection of Coordination Geometry to Adjust Water Exchange Rates of Paramagnetic Metal Ion-Based Macrocyclic Contrast Agents

AD Sherry, M Woods and Z Kovacs
US Patent Filed: July 2003.

Thin film fiber optic electrode sensor array and apparatus for concurrent viewing and chemical sensing of a sample

P Pantano, ES Jin, SS Khan and HW Stokes, Jr.
U.S. Patent  # US 6487326 B1. Filed: Nov 29, 1999. Issued: Nov 26, 2002.

Methods for Determining Gluconeogenesis, Anapleurosis, and Pyruvate Recycling

J Jones, AD Sherry, FMH Jeffrey, GL Cottam and CR Malloy
U.S. Patent 6,329,208. Filed: July 16, 1998; Issued: December 11, 2001.

Determination of Intracellular Sodium and Potassium Ions by NMR

AD Sherry, CR Malloy and N Bansal
U.S. Patent 5,951,473. Filed: 5/24/94; Issued: 9/14/99.

Polyazamacrocyclofluoromonoalkylphosphonic Acids and Their Complexes for use as Contrast Agents

AD Sherry and GE Kiefer
European Patent Issued, 10/27/98.

13C Isotopomer Analysis in Intact Tissues using {13C}Homonuclear Decoupling

AD Sherry, CR Malloy, and P Zhao
U.S. Patent 5,597,548. Filed: 7/3/95. Issued: 1/28/97.

Polyazamacrocyclic Compounds for Complexation of Metal Ions

AD Sherry and GE Kiefer
European Patent Issued, 11/21/97.

Phosphorylated Polyazamacrocyclic Compounds for Complexation of Metal Ions

AD Sherry and GE Kiefer
U.S. Patent 5,630,997. Filed: 11/8/94. Issued: May 20, 1997.

Molecular Sieve-Enclosed Transition and Rare Earth Metal Ions as Contrast Agents for the Gastrointestinal Tract

S Young, K Balkus, and AD Sherry
Japanese Patent Issued: November 7, 1997.

Molecular Sieve-Enclosed Transition and Rare Earth Metal Ions as Contrast Agents for the Gastrointestinal Tract

S Young, K Balkus, and AD Sherry
Singapore Patent 9607688-0 Issued: November 14, 1997.

Polyazamacrocyclic Compounds for Complexation of Metal Ions

AD Sherry, I Lazar, E Brucher and R Ramasamy
European Patent Issued, 10/23/96.

Method of Determining Sources of Acetyl-CoA Under Nonsteady-State Conditions

CR Malloy and FMH Jeffrey
U.S. Patent 5,413,917. Filed: July 18, 1990. Issued: May 9, 1995.

Carboxamide Modified Polyamine Chelators and Radioactive Complexes Thereof for Conjugation to Antibodies

WJ Kruper, Jr., WA Fordyce and AD Sherry
U.S. Patent 5,739,322. Filed: Apr. 13, 1.995  Issued:  April 14, 1998.

Polyazamacrocycles for Complexation of Metal Ions

AD Sherry, I Lazar, E Brucher and R Ramasamy
U.S. Patent 5,342,606  Filed: November 19, 1990 Issued: Aug. 30, 1994.

Synthesis if Polyazamacrocyles with More Than One Type of Side-Chain Chelating Group (MRI methods)

AD Sherry and J van Westrenen
U.S. Patent 5,316,757 Filed: December 13, 1.991 Issued: May 31, 1994.

Synthesis if Polyazamacrocyles with More Than One Type of Side-Chain Chelating Group (Synthetic method, composition)

AD Sherry and J.van Westrenen
U.S. Patent 5,428,155.  Filed:  May 27, 1994. Issued: June 27, 1995.

Preparation of 1,4,10,13-Tetraoxa-7,16-Diazacyclooctadecane Metal Chelates and Salts as Radioprotectants

J Emri, B Gyori, Z Kovacs, E Brucher, LB Sztanyik and L Varga
PCT Int. Appl. WO 91 10,655 (1991) (Chem. Abst. 1991, 115, 183388t); US5,440,031 (1995).

Alkyl Phosphonate Polyazamacrocyclic Chelates for MRI

AD Sherry and GE Kiefer
U.S. Patent 5,362,476. Filed: July 13, 1992; Issued:  Nov. 8, 1994.

Zeolite-Enclosed Transition and Rare Earth Metal Ions as Contrast Agents for the Gastrointestinal Tract

K Balkus, AD Sherry and S Young
U.S. Patent 5,122,363.  Filed: Dec. 7, 1990 Issued: Jun. 16, 1992.

Carboxamide Modified Polyamine Chelators and Radioactive Complexes Thereof for Conjugation to Antibodies

WJ Kruper, Jr., WA Fordyce and AD Sherry
U.S. Patent 5,310,535.  Filed:  Apr. 24, 1992 Issued:  May 10, 1994.

Triazamacrocyclic NMR Contrast Agents and Methods for Their Use

AD Sherry
U.S. Patent 4,983,376 Filed: Dec. 28, 1988 Issued: Jan. 8, 1991.

NMR Contrast Agents and Methods For Their Use

AD Sherry
U.S. Patent 4,983,376. Filed: Dec. 28, 1988. Issued: January 8, 1991.

Using Polyazamacrocyclic Compounds for Intracellular Measurement of Metal Ions Using MRS

AD Sherry, I Lazar, E Brucher and R Ramasamy
U.S. Patent 5,188,816  Filed:  November 26, 1991 Issued: February 23, 1993. 

Molecular Sieve-Enclosed Transition and Rare Earth Metal Ions as Contrast Agents for the Gastrointestinal Tract

S Young, K Balkus, and AD Sherry
U.S.Patent 5,429,814. Filed: December 7,1990. Issued: July 4, 1995.

Gadolinium Chelates as NMR Contrast Agents

AD Sherry
U.S. Patent 4,639,365 Filed: Oct. 18, 1984. Issued: Jan 27, 1987.

High Affinity VEGF-Receptor Antagonists

T Kodadek, DG Udugamasooriya, and RA Brekken
(USTD:1918).
Patent application number: 20110077201 Filed Jul. 10, 2007

Peptoid ligands for Isolation and Treatment of Autoimmune T Cells

T Kodadek, A Gocke, DG Udugamasooriya
(USTD:2121). Filed:  May 28, 2010

High density lipoprotein-like peptide-phospholipid scaffold (HPPS) Nanoparticles

G Zheng, ZH Zhang, I Corbin, J Chen
WO 2009/073984 A1.