Pharmacological Sciences Faculty

David Mangelsdorf, Ph.D.
Track Chair


Joseph Albanesi, Ph.D.
Professor
Research Interests: Mechanisms of membrane fusion; role of lipids in membrane trafficking; membrane vesiculation of dynamin


Steven Altschuler, Ph.D.
Associate Professor
Altschuler/Wu Lab
Research Interests: Single cell perturbation analysis of cell signaling pathways


Rolf A. Brekken, Ph.D.
Associate Professor
Brekken Lab
Research Interests: Tumor-host interactions in pancreatic cancer


Yuh Min Chook, Ph.D.
Associate Professor
Chook Lab
Research Interests: Structures and mechanisms of nuclear transport and the nuclear pore complex


Melanie Cobb, Ph.D.
Professor
Research Interests: Protein kinase cascades; MAP kinases; signal-transduction mechanisms


David R. Corey, Ph.D.
Professor
Corey Lab
Research Interests: Engineering proteins and nucleic acids for novel function


J. R. Falck, Ph.D.
Professor
Falck Lab
Research Interests: Total synthesis of natural products; synthetic methodology; organometallics; eicosanoids; medicinal chemistry


Kevin H. Gardner, Ph.D.
Professor
Gardner Lab
Research Interests: NMR-based structural studies of proteins involved in transcriptional regulation


Alfred Gilman, M.D., Ph.D.
Regental Professor Emeritus
Professor Emeritus
Research Interests: Hormonal regulation of cyclic AMP metabolism; mechanisms of control of hormone-sensitive adenylate cyclase; regulatory GTP-binding proteins


Joel Goodman, Ph.D.
Professor
Goodman Lab
Research Interests: Intracellular sorting of newly synthesized proteins; organelle biogenesis and membrane structure and function; the yeast peroxisome as a model of organellar assembly


Jin Jiang, Ph.D.
Professor
Jiang Lab
Research Interests: Signal-transduction pathways in development and human disease; genetic control of organ growth and patterning; tumor suppressor genes


Jane E. Johnson, Ph.D.
Professor
Johnson Lab
Research Interests: Molecular biology of mammalian neural development


Steven Kliewer, Ph.D.
Professor
Mangelsdorf/Kliewer Lab
Research Interests: Physiology of nuclear receptors


Mark Lehrman, Ph.D.
Professor
Lehrman Lab
Research Interests: Informational carbohydrates in the endoplasmic reticulum:  roles in protein folding, stress responses, and human disease


David Mangelsdorf, Ph.D.
Professor
Mangelsdorf/Kliewer Lab
Research Interests: Mechanism of nuclear hormone receptor action; role of retinoids in cancer; transcriptional regulation of lipid metabolism


John Minna, M.D.
Professor
Research Interests: Molecular genetics of human cancer; growth factors, and signal transduction in human tumors


Margaret Phillips, Ph.D.
Professor
Phillips Lab
Research Interests: Polyamine and pyrimidine metabolism in trypanosome and malaria parasites


Rama Ranganathan, M.D., Ph.D.
Professor
Ranganathan Lab
Research Interests: Structural basis for signal processing in Drosophila photoreceptors


Jose Rizo-Rey, Ph.D.
Professor
Rizo-Rey Lab
Research Interests: Structural analysis by nuclear magnetic resonance of proteins involved in calcium-triggered synaptic vesicle exocytosis


Michael Rosen, Ph.D.
Professor
Rosen Lab
Research Interests: Analysis of the structural, biochemical, and cell biological mechanisms that regulate the actin cytoskeleton


Elliott Ross, Ph.D.
Professor
Ross Lab
Research Interests: Mechanisms and regulatory behavior of G-protein signaling; regulated protein-protein interactions in signal transduction


Dean Smith, M.D., Ph.D.
Associate Professor
Smith Lab
Research Interests: Sensory transduction in Drosophila melanogaster


Paul Sternweis, Ph.D.
Professor
Research Interests: Regulation of intracellular events by cell-surface receptors; structure and function of GTP-dependent regulatory proteins and their effectors


Ronald Taussig, Ph.D.
Associate Professor
Research Interests: G protein-mediated signaling


Jonathan Terman, Ph.D.
Assistant Professor
Terman Lab
Research Interests: Axonal growth and guidance; neuronal connectivity; axonal regeneration


Thomas Wilkie, Ph.D.
Associate Professor
Wilkie Lab
Research Interests: Signal-transduction pathways in mammalian development and energy homeostasis


Lani Wu, Ph.D.
Associate Professor
Altschuler and Wu Lab
Research Interests: Design principles in biological networks


Hongtao Yu, Ph.D.
Professor
Yu Lab
Research Interests: Study of cell division cycle


Guang Zhao
Research Interests: Growth factor-mediated signal transduction in embryonic stem-cell biology, germ-cell fate determination and nuclear reprogramming


Yingming Zhao, Ph.D.
Associate Professor
Research Interests:
Functional proteomics and mass spectrometry