Computational and Systems Biology Faculty

Steven Altschuler, Ph.D. (UC San Diego, Mathematics)
Associate Professor
Altschuler and Wu Lab
Research Interests:
Understanding the origins, functions, and consequences of signaling heterogeneity in cancer and metabolism


Min Chen, Ph.D. (University of Texas at Austin, Statistics)
Assistant Professor
Research Interests:
Statistical and computational methods for problems in molecular biology and genetics; microarray; GWAS; next generation sequencing; pathway-based genomics analysis; eQTL


Johann Deisenhofer, Ph.D. (Technical University of Munich, Physics)
Professor
Regental Professor
Deisenhoffer Lab
Research Interests: Structural biology; membrane proteins; protein stability and function


Kevin Gardner, Ph.D. (Yale University, Molecular Biophysics and Biochemistry)
Professor
Gardner Lab
Research Interests:
Biophysical and biochemical studies of photoreceptors and other signaling proteins


Nick Grishin, Ph.D. (UT Southwestern, Molecular Biophysics)
Associate Professor
Grishin Lab
Research Interests:
Computational biology; analysis of protein sequences and structures


Robin Hiesinger, Ph.D. (University of Freiburg)
Assistant Professor
Hiesinger Lab
Research Interests:
Neurogenetics; brain wiring, synaptic specification and function in Drosophila; computational approach to 4D visualization


Khuloud Jaqaman, Ph.D.
Assistant Professor
Jaqaman Lab
Research Interests: Quantitative single-molecule imaging of receptor organization and signaling; linking molecular and cellular behavior across multiple scales; computational image analysis and data multiplexing


Zbyszek Otwinowski, Ph.D. (University of Chicago, Biochemistry)
Associate Professor
Otwinowski Lab
Research Interests:
Three-dimensional structures of biological molecules


Rama Ranganathan, MD, Ph.D.(UC San Diego, Biology)
Professor
Ranganathan Lab
Research Interests: Structural basis for signal processing in Drosophila photoreceptors


Luke Rice, Ph.D.  (Yale University, Molecular Biophysics and Biochemistry)
Assistant Professor
Rice Lab
Research Interests:
Integrating structure, kinetics, and computation to understand the molecular determinants and regulatory mechanisms of microtubule dynamics


Michael Rosen, Ph.D. (Harvard University, Organic Chemistry)
Professor
Rosen Lab
Research Interests:
Study directed toward understanding the structural, biochemical and cell biological mechanisms of cytoskeletal regulation by the Rho GTPases, with long term objective of quantitative understand of how the cytoskeleton integrates biological inputs to create complex but coherent outputs


Elliott Ross, Ph.D. (Cornell University, Biochemistry) 
Professor
Ross Lab
Research Interests:
Mechanisms of G-protein signaling; amplification, selectivity, response timing; structure/function of GTPase-activating proteins and associated receptors


Lani Wu, Ph.D. (UC San Diego, Mathematics)
Associate Professor
Altschuler and Wu Lab
Research Interests:
Identifying design principles underlying signaling networks in cell polarity and migration


Guanghua (Andy) Xiao, Ph.D. (University of Minnesota, Statistics)
Assistant Professor
Xiao Lab
Research Interests:
Statistical methods for genomics/proteomics and in spatial/image analysis


Xian-Jin Xie, Ph.D. (University of Iowa, Biostatistics)
Associate Professor
Research Interests:
Model diagnosis and goodness-of-fit tests; survival analysis and categorical data analysis; methods on correlated data


Yang Xie, Ph.D.
Assistant Professor
Research Interests:
Processing and analysis of high throughput data; false discovery rate estimation; integrated analysis methodology; Bayesian analysis methodology; design and analysis of clinical trials


Chin-Rang Yang, Ph.D. (University of Wisconsin, Human Oncology and Developmental Biology)
Assistant Professor
Research Interests:
Computational reconstruction of biological networks; in silico biology; biological data mining