Cell Regulation Faculty

Paul Sternweis, Ph.D.
Program Chair
Professor
Research Interests: Regulation of intracellular events by cell-surface receptors; structure and function of GTP-dependent regulatory proteins and their effectors


Joseph Albanesi, Ph.D.
Professor
Research Interests: Mechanisms of membrane fusion; role of lipids in membrane trafficking; membrane vesiculation of dynamin


Neal Alto, Ph.D.
Associate Professor
Alto Lab
Research Interests: The intersection between human signal-transduction and bacterial pathogenesis; use of biochemical and cell biological analysis to define molecular mechanisms of microbial infectious disease


Steven Altschuler, Ph.D.
Associate Professor
Altschuler Lab
Research Interests: Design principles underlying the spatial-temporal organization of molecular networks


James Bibb, Ph.D.
Associate Professor
Bibb Lab
Research Interests: Protein phosphorylation/dephosphorylation related to neural function


Michael Brown, M.D.
Professor
Brown-Goldstein Lab
Research Interests: Regulation of gene expression; cell-surface receptor function; genetics and biochemistry of lipoprotein and cholesterol metabolism


Cheng-Ming Chiang, Ph.D.
Professor
Chiang Lab
Research Interests: Mechanisms of transcriptional regulation and epigenetic control; chromatin remodeling and histone tail modification; sumoylation and ubiquitination; functional interplay between oncoproteins and tumor suppressor proteins; general transcription factors and cofactors


Melanie Cobb, Ph.D.
Professor
Research Interests: Protein kinase cascades; MAP kinases; signal-transduction mechanisms


Russell DeBose-Boyd, Ph.D.
Professor
DeBose-Boyd Lab
Research Interests: Regulation of HMG-CoA reductase and sterol metabolism


Joseph Goldstein, M.D.
Professor
Brown-Goldstein Lab
Research Interests: Genetics and biochemistry of lipoprotein and cholesterol metabolism; cell-surface receptor function; regulation of gene expression


Joel Goodman, Ph.D.
Professor
Goodman Lab
Research Interests: Intracellular sorting of newly synthesized proteins; organelle biogenesis and membrane structure and function; the yeast peroxisome as a model of organellar assembly


F. Kent Hamra, Ph.D.
Assistant Professor
Hamra Lab
Research Interests: Signal transduction pathways that regulate stem cell development; application of sperm stem cells to biology and medicine


Jer-Tsong (J.T.) Hsieh, Ph.D.
Professor
Research Interests: Human cancer gene therapy; signaling defects in urogenital cancers


Lily Huang, Ph.D.
Assistant Professor
Huang Lab
Research Interests: Cytokine receptor; signal transduction; hematopoiesis; structure-function analysis of protein; cancer 


Khuloud Jaqaman, Ph.D.
Assistant Professor
Jaqaman Lab
Research Interests: Quantitative single-molecule imaging of receptor organization and signaling; linking molecular and cellular behavior across multiple scales; computational image analysis and data multiplexing.


Steve Jiang, Ph.D.
Professor
Research Interests:  


Steven Kliewer, Ph.D.
Professor
Mangelsdorf-Kliewer Lab
Research Interests: Physiology of nuclear receptors


Mark Lehrman, Ph.D.
Professor
Lehrman Lab
Research Interests: Informational carbohydrates in the endoplasmic reticulum: roles in protein folding, stress responses, and human disease


Jen Liou, Ph.D.
Assistant Professor
Research Interests: Spatial and temporal regulation of cellular signaling events; mechanisms and physiological roles of store-operated calcium signaling


James Malter, M.D. 
Professor
Malter Lab
Research Interests: Post-transcriptional gene regulation and signaling in the immune and nervous system. 


David Mangelsdorf, Ph.D.
Professor
Mangelsdorf-Kliewer Lab
Research Interests: Mechanism of nuclear hormone receptor action; role of retinoids in cancer; transcriptional regulation of lipid metabolism


Denise Marciano, M.D.,  Ph.D.
Assistant Professor
Marciano Lab
Research Interests: Regulation of cell-cell adhesion during tubule and glomerular formation and in polycystic kidney disease


Carole Mendelson, Ph.D.
Professor
Mendelson Lab
Research Interests: Molecular mechanisms in tissue-specific, developmental, and hormonal regulation of eukaryotic gene expression


John Minna, M.D.
Professor
Research Interests: Molecular genetics of human cancer; growth factors and signal transduction in human tumors


Kate Luby-Phelps, Ph.D.
Professor
Research Interests: Light microscope imaging of structure and function in living cells and tissues


Ryan Potts, Ph.D. 
Assistant Professor
Potts Lab
Research Interests: Role of ubiquitin ligases in tumor initiation and progression, vesicular trafficking, and genome stability. 


Rama Ranganathan, M.D., Ph.D.
Professor
Ranganathan Lab
Research Interest: Biophysical mechanisms that underlie cellular signal transduction in sensory neurons


Michael Reese, Ph.D.
Assistant Professor
Reese Lab
Research Interests:  


Daniel Rosenbaum, Ph.D.
Assistant Professor
Rosenbaum Lab
Research Interests: Structure and mechanism of integral membrane signaling proteins


Elliott Ross, Ph.D.
Professor
Ross Lab
Research Interests: Mechanisms and regulatory behavior of G-protein signaling; regulated protein-protein interactions in signal transduction


Michael Roth, Ph.D.
Professor
Roth Lab
Research Interests: Recognition and sorting of cell-surface glycoproteins


David Russell, Ph.D.
Professor
Russell Lab
Research Interests: Steroid and bile-acid metabolism; molecular genetics; gene regulation; protein structure-function


Amit Sawant, Ph.D.
Assistant Professor
Research Interests: 


Philipp Scherer, Ph.D.
Professor
Scherer Lab
Research Interests: Identification and physiological characterization of novel secretory proteins that serve as potential links between the adipocyte and the processes of whole body energy homeostasis; inflammation and cancer; beta cell biology


Sandra Schmid, Ph.D.
Professor
Schmid Lab
Research Interests: Mechanisms governing and regulation of clathrin-mediated endocytosis, structure and function of the GTPase dynamin


Joachim Seemann, Ph.D.
Associate Professor
Seeman Lab
Research Interest: Biogenesis of the Golgi apparatus


Dean Smith, M.D., Ph.D.
Professor
Smith Lab
Research Interest: Sensory transduction in Drosophila melanogaster


William Snell, Ph.D.
Professor
Snell Lab
Research Interests: Cell-cell interactions and signal transduction during fertilization in Chlamydomonas; cellular and molecular mechanisms of cell-cell fusion


Ronald Taussig, Ph.D.
Associate Professor
Research Interest: G protein-mediated signaling


Lance Terada, M.D.
Professor
Research Interests: Vascular biology; oxidant biochemistry; signal transduction; acute lung injury


Michael White, Ph.D.
Professor
White Lab
Research Interests: Molecular mechanisms for control of cell growth and differentiation


Angelique Whitehurst, Ph.D.
Assistant Professor
Whitehurst Lab
Resaearch Interests:  


Lani Wu, Ph.D.
Associate Professor
Altschuler/Wu Lab
Research Interest: Design principles underlying the formation of cellular polarity


Helen Yin, Ph.D.
Professor
Yin Lab
Research Interest: Mechanisms for signal transduction through the actin cytoskeleton


Gang Yu, Ph.D.
Associate Professor
Yu Lab
Research Interests: Biochemistry of signal transduction, gene regulation, and membrane protein complexes; molecular and cellular mechanisms of neurogenesis, neuroplasticity, and neurodegeneration


Hongtao Yu, Ph.D.
Professor
Yu Lab
Research Interest: Study of cell division cycle