Clinical Research Design and Analysis (DCS 5301)

Clinical Research Design & Analysis is designed to teach basic and intermediate level principles in research design, formulation of the research question, identifying primary and secondary hypotheses, types of experimental structures, use of control groups and pre-specified hypotheses, surrogate measurements, analysis of incomplete data, meaning of P values and confidence intervals, identification of bias, and flaws in study design. Course objectives are:

  1. Formulation of the research question
  2. Identification of primary and secondary hypotheses
  3. Understand types of experimental structures
  4. Use of control groups and pre-specified hypotheses
  5. Understand surrogate measurements
  6. Analysis of incomplete data
  7. Meaning of P values and confidence intervals
  8. Identification of bias and flaws in study design

Prerequisites: None

Credit: 3 credit hours, required for all program students

Grading Criteria: Pass/Fail, based on the following requirements: research protocol assignments, presentation of research protocol to the class, final examination with 60 multiple choice questions, and attendance. It is strongly recommended that students attend all sessions.

Semester Offered: Fall

Course Director:
Milton Packer, MD
Professor and Chair
Dept. of Clinical Sciences
Phone: 214-648-0491
Fax: 214-648-6417

Course Administrator:
Mack Dressler
Dept. of Clinical Sciences
Phone: 214-648-2558
Fax: 214-648-3494