Postdoctoral Training Opportunities

UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. In accordance with federal and state law, the University prohibits unlawful discrimination, including harassment, on the basis of: race; color; religion; national origin; gender, including sexual harassment; age; disability; citizenship; and veteran status. In addition, it is UT Southwestern policy to prohibit discrimination on the basis of sexual orientation, gender identity, or gender expression.

Advanced Imaging Research Center Hematology Oncology, Internal Medicine Pathology
Biochemistry Human Growth and Development, Eugene McDermott Center
Pediatrics
Biophysics Hypertension, Internal Medicine Pharmacology
Cancer, Simmons Cancer Center Immunology Physiology
Cardiology, Internal Medicine Infectious Diseases, Internal Medicine Plastic Surgery
Cardiothoracic Surgery Microbiology Psychiatry
Cell Biology Mineral Metabolism, Internal Medicine Pulmonary, Internal Medicine
Center for Human Nutrition Molecular Biology
Radiation Oncology
Children's Research Institute at UT Southwestern Molecular Genetics
Radiology
Clinical Sciences
Nephrology, Internal Medicine Surgery
Dermatology Neurology and Neurotherapeutics Systems Biology, Cecil H. and Ida Green Center
Developmental Biology Neuroscience Therapeutic Oncology Research, Hamon Center
Digestive and Liver Diseases, Internal Medicine Obstetrics & Gynecology Urology
Endocrinology Ophthalmology
Genetics of Host Defense Center
Otolaryngology - Head & Neck Surgery

Advanced Imaging Research Center

Chemistry for Molecular Imaging (344)

The UT Southwestern Medical Center has recently established the Cyclotron and Radiochemistry Program, which encompasses a GE PETTrace cyclotron, three small animal scanners (a Siemens Inveon PET/CT Multimodality System, a Bioscan NanoSPECT/CT Plus system, and an ASPECT M2 1T MRI system), and state-of-the-art chemistry and radiochemistry laboratories and quality assurance facilities equipped with high-end analytical instruments including ICP/MS, Q-TOF LC/MS, FPLC, and HPLC. With research focus on design, synthesis, and biological evaluations of targeted imaging probes for noninvasive disease detection and therapy assessment, the Program is poised to stand at the forefront of molecular imaging.

The Program has an immediate opening for a postdoctoral researcher for design and synthesis of molecular imaging probes. Candidates with Ph.D. in synthetic or medicinal chemistry and career interests in molecular imaging are encouraged to apply. Hands-on experience with small animal imaging, medical radioisotopes, and live animals is desirable but not required. Interested individuals should send current curriculum vitae and contact information for three references to:

Hancheng Cai, Ph.D.
Assistant Professor
Department of Radiology and Advanced Imaging Research Center
Chief Radiochemist, Cyclotron and Radiochemistry Program
UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75390-8542
hancheng.cai@utsouthwestern.edu

Neuroimaging and Brain Connectivity (334)

The Advanced Imaging Research Center (AIRC) at UT Southwestern Medical Center is seeking a postdoctoral scholar with strong physical and neuroanatomical background. The candidate must have a Ph.D. or equivalent and should have a background in biomedical engineering, electronic engineering, biophysics, computer science or other related areas. Outstanding candidates with experience in diffusion MRI data acquisition/analysis, tractography analysis, and image analysis of developing brain connectome are encouraged to apply. Good computer programming skills in Matlab and C will be a plus.

Consideration of applications will begin immediately and continue until the position is filled. To apply send a CV, a brief statement of research interest, and contact information of three references to:

Hao Huang, Ph.D.
Advanced Imaging Research Center
University of Texas Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75390-8542
Phone: 214-645-2881
Fax: 214-645-2885
hao.huang@utsouthwestern.edu 

Brain MR Spectroscopy (332)

The Advanced Imaging Research Center (AIRC) at UT Southwestern Medical Center is seeking one or two postdoctoral researchers to work in magnetic resonance spectroscopy (MRS) and imaging (MRI). We have several on-going MR projects developing new data acquisition/analysis strategy and applications in brain tumors in humans and animals. AIRC possesses research-dedicated several 3T and 7T whole-body MR scanners (Philips) and 9.4T horizontal-bore animal MR scanner (Agilent).

Candidates should have a Ph.D. or equivalent and background in experimental MRS/MRI. Outstanding candidates with experience in 1H/13C MRS data acquisition/analysis and MR sequence programming in the Philips environments are encouraged to apply. Good computer programming skills in MATLAB and C will be a plus.

Consideration of applications will begin immediately and continue until the position is filled.

To apply, send a CV with three references and a brief statement of research interest to:

Changho Choi, Ph.D.
Advanced Imaging Research Center
University of Texas Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75390-8542
Phone: 214-645-2805
Fax: 214-645-2885
changho.choi@utsouthwestern.edu

Non-Small Cell Lung Carcinoma (327)

A postdoctoral position is available in the laboratory of Matthew Merritt, Ph.D., in the Advanced Imaging Research Center of UT Southwestern Medical Center to study the effects of a novel treatment on the progression of non-small cell lung carcinoma. Our laboratory has several exciting projects related to physical, biological and medical sciences.

Candidates must hold a Ph.D. and/or M.D. degree. Projects will utilize NMR and/or MRI if necessary, and candidates with additional experience in intermediary metabolism considered are strongly encouraged to apply. Experience leading to publication in peer-reviewed journals is recommended.

Interested individuals should send a CV, statement of interests, and a list of three references to:
Matthew Merritt, Ph.D.
UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75390-9185
matthew.merritt@utsouthwestern.edu

Biochemistry, Department of

Glucose Signaling in Lipogenesis (351)

A postdoctoral position is available in the laboratory of Kosaku Uyeda, Ph.D., in the Department of Biochemistry to study the mechanisms of action and regulation of a transcription factor discovered in this laboratory, termed “Carbohydrate response element binding protein, ChREBP.” ChREBP is one of two essential transcription factors in liver responsible for lipogenesis. ChREBP increases the transcription of all lipogenic enzyme genes in response to high carbohydrate diets. Ongoing investigations use biochemical, and physiological techniques to characterize the mechanism of glucose signaling and structure-function relationship of ChREBP to regulate fat synthesis. We are seeking candidates with biochemical, molecular biology, or obesity/diabetes interest and backgrounds that have earned a Ph.D. or M.D. degree in one of those areas.
CV’s and references should be sent to Dr. Uyeda at kosaku.uyeda@utsouthwestern.edu

Mass Spectrometry and Protemics (325)

A postdoctoral position is available in the Mirzaei Lab in the Department of Biochemistry at the University of Texas Southwestern Medical Center. This position is made available by funding from the Welch Foundation. This position is for one year, and reappointment beyond the first year of employment is contingent upon the availability of funding and satisfactory performance.

The successful applicant will have the opportunity to work on developing technology for identification of protein targets of small molecule drug candidates. The position will involve tissue culture, advanced HPLC, mass spectrometry utilizing the proteomics core facility at UT Southwestern led by Dr. Mirzaei, and bioinformatics. The mass spectrometry center at UTSW employs some of the most advanced instruments including QExactive plus, Orbitrap Elite, Quantiva, and 6500 Qtrap which will be available to the postdoctoral trainee.

Applicants must have a Ph.D. in Analytical Chemistry, Biochemistry, Chemistry, Biology, or related closely field. Proven track record of successful research and publication is required. Experience in HPLC, mass spectrometry, molecular biology, and biochemistry is highly valued.

Applications should be submitted online and must include a cover letter, full curriculum vitae, and statement of research interests. Three letters of reference should also be emailed directly to Dr. Mirzaei at hamid.mirzaei@utsouthwestern.edu.

Cancer Biomarker, Targeted Proteomics (326)

A postdoctoral position is available in the Mirzaei Lab in the Department of Biochemistry at the University of Texas Southwestern Medical Center. This position is made available by funding from Cancer Prevention Research Institute of Texas. This position is for one year, and reappointment beyond the first year of employment is contingent upon the availability of funding and satisfactory performance.

The successful applicant will work closely with members of Mirzaei lab, the proteomics core facility at UT Southwestern, and cancer center members pursuing high priority cancer targets. Thus, a dynamic, transdisciplinary and collaborative perspective will be highly valued. The mass spectrometry center at UTSW employs some of the most advanced instruments including QExactive plus, Orbitrap Elite, Quantiva and 6500 Qtrap which will be available to the postdoctoral trainee. This recruitment is for a project that is focused on developing SRM based biomarker assays in cancer. The position will involve tissue handling and processing, mass spectrometry and bioinformatics.

Applicants must have a Ph.D. in Analytical Chemistry, Biochemistry, Chemistry, Biology, or related closely field. Proven track record of successful research and publication is required. Experience in HPLC, mass spectrometry, molecular biology, and biochemistry is highly valued.

Applications should be submitted online and must include a cover letter, full curriculum vitae, and statement of research interests. Three letters of reference should also be emailed directly to Dr. Mirzaei at hamid.mirzaei@utsouthwestern.edu.

Biophysics, Department of

Biochemical and Biophysical investigation of RNA-mediated Gene Regulation (339)

The research group of Yunsun Nam, Ph.D. at UT Southwestern Medical Center is seeking a postdoctoral scholar. Our laboratory is housed in newly renovated space at the heart of the Cecil H. and Ida Green Center for Reproductive Biology Sciences, Department of Obstetrics and Gynecology at UT Southwestern Medical Center.

The overarching goal of our group is to elucidate the mechanistic details of RNA-regulated gene expression, by investigating the structure-function relationship of various protein/nucleic acid complexes. We are particularly interested in the gene regulation pathways relevant to mammalian development and cancer. Postdoctoral scholars will have many opportunities to learn the newest methods in biochemistry and biophysics, in addition to working in an exciting, fast-evolving area in the field of biological and biomedical sciences. We use various approaches, including X-ray crystallography, NMR spectroscopy, molecular biology, nucleic acid and protein biochemistry, high throughput sequencing, and eukaryotic cell-based studies. For more information, please refer to the Yunsun Nam Lab website.

Candidates must have a Ph.D. degree and a strong background in biochemistry (protein or nucleic acid) and/or structural biology. Interested individuals should submit a CV as a single pdf file, including contact information for 3 references, by email to: yunsun.nam@utsouthwestern.edu.

Cancer, Simmons Cancer Center

Molecular Mechanisms Regulating Tumor Maintenance (358)

The Division of Hematology/Oncology and Simmons Cancer Center of UT Southwestern Medical Center are seeking two postdoctoral positions in the laboratory of Pier Paolo Scaglioni, M.D.

Areas of interest include:

  1. Cancer Metabolism: Characterization of the role of mutant KRAS in reprogramming lipid biogenesis in lung cancer.
  2. Cancer maintenance: Identification of the mechanisms that mediate the maintenance of mutant KRAS lung cancer. 
  3. Regulation of oncogenic networks: Study of the role of the SUMO E3 ligase PIAS1 in the regulation of PML nuclear bodies and c-MYC.

These research topics will be addressed with a combination of molecular/cellular biology techniques and mouse cancer models.

Position Requirements: Candidates must hold an M.D. and/or a Ph.D. degree. Experience in the field of cellular/cancer biology leading to publication in peer-reviewed journals is recommended.

Interested individuals should send the following information:

  1. A statement of interest explaining why the candidate is interested in the position and how the position might further the candidate’s career goals. 
  2. An updated CV.
  3. Names and contact information of three references.

Pier Paolo Scaglioni, M.D.
Assistant Professor
UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75390-8852
pier.scaglioni@utsouthwestern.edu
Scaglioni Lab

The role of gametogenic proteins in cancer (340)

A postdoctoral position is available in the laboratory of Angelique Whitehurst in the Simmons Cancer Center of UT Southwestern Medical Center to study the role of tumor-activated gametogenic proteins in supporting tumorigenic behaviors. Our laboratory has a number of projects related to cancer biology and the role of anomolously expressed proteins in tumorigenesis.

Candidates must hold a Ph.D. and/or M.D. degree. Experience in cell or molecular biology, biochemestry, and/or whole animal models is preferred. Applicants should have at least one first-author publication in a peer-reviewed journal.
Interested individuals should send a CV, statement of interests, and a list of three references to:
Angelique Whitehurst, Ph.D.
UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75390-8807
angelique.whitehurst@utsouthwestern.edu
Whitehurst Lab

Bioinformatics, Genomics and Personalized Medicine in Kidney Cancer (337)

A postdoctoral position is available for a highly-motivated scholar to work in the area of genomics and personalized medicine in kidney cancer. The project is focused on integrating high-throughput data from next-generation sequencing, gene expression, and other genetic and epigenetic analyses using clinical samples and pre-clinical models. The successful candidate will have the opportunity to be part of a team made up of researchers, physicians and clinical geneticists that cares for patients with kidney cancer and will be involved in the evaluation of personalized patient cancer genomes. The ultimate goal is to leverage understanding of the molecular genetics and biology of kidney cancer to improve patient treatments. For more information about the research program, please see, http://www3.utsouthwestern.edu/brugarolaslab/.

Candidates must have a Ph.D. in statistical genetics, bioinformatics, computer science, or a related field. The candidate should also have programming experience using Python, Perl, Java, or C/C++ and be familiar with tools such as R/Bioconductor or Matlab. A track record of productivity is essential. Successful applicants will have the opportunity to work in a translational research program spanning from molecular genetics to the clinic.

Interested candidates should send a CV, statement of research interests and the names of three references to:
James Brugarolas, M.D., Ph.D.
5323 Harry Hines Blvd.
Dallas, TX 75390-9133
james.brugarolas@utsouthwestern.edu

Molecular Mechanisms and Translational Research in Kidney Cancer (336)

A postdoctoral research scholar position is available in the Brugarolas lab for a highly-motivated scholar to study signaling mechanisms in renal cancer. For more information, visit the lab website

Candidates must hold a Ph.D. degree and have a track record of productivity with publications in well-established journals. Successful applicants will have the opportunity to work in a translational research program spanning from the molecular genetics to the clinic.

Interested candidates should send a CV, statement of research interests and the names of three references to:
James Brugarolas, M.D., Ph.D.
5323 Harry Hines Blvd.
Dallas, TX 75390-9133
james.brugarolas@utsouthwestern.edu

Cell Stress and Cancer Nanomedicine (335)

A postdoctoral position is now open for research focused on the effects of tumor-specific ‘NAD(P)H:quinone oxidoNQO1 bioactivatable’ drugs on altering cancer metabolism. The project will also develop novel noninvasive cancer imaging modalities of cancer metabolism.

Prospective candidates will have the opportunity to work in a highly productive multi-disciplinary environment with a team of experts in basic research using state-of-the-art cancer metabolism and imaging technology. Funding provided by a grant from the Pancreatic Action Network and American Association for Cancer Research. Salary will be dictated by NIH guidelines and the position is open only for junior postdoctoral candidates.

Applicants must hold a Ph.D. degree with strong background in cancer biology, molecular biology, and cancer metabolism. Candidates just out of their Ph.D. training will be preferred.

Please email curriculum vitae (CV), as well as names and contact information of three (3) references to:

David A. Boothman, Ph.D.
Professor, Department of Pharmacology
Associate Director for Translational Research
Simmons Comprehensive Cancer Center
University of Texas Southwestern Medical Center
Dallas, TX 75390-8807
david.boothman@utsouthwestern.edu

Chromatin Transcriptional Regulation (328)

A postdoctoral position is available to study mechanisms of chromatin-dependent transcription and posttranslational modification of transcription factors, cofactors and the general transcription machinery. In vitro-reconstituted chromatin transcription systems are frequently used in the lab to identify factors and pathways leading to gene activation and repression. Current focuses include transcription mechanisms and chromatin dynamics regulated by p53, AP-1, HPV-encoded E2 and E6 proteins, and Brd4 BET family proteins.

The candidate must have a Ph.D. and a strong background in transcription, chromatin, protein biochemistry, molecular biology is preferred.

Please forward your CV and names of three referees to:
Cheng-Ming Chiang, Ph.D.
Simmons Comprehensive Cancer Center
UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75390-8807
Phone: 214-645-6128
Fax: 214-645-6347
cheng-ming.chiang@utsouthwestern.edu

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Cell Biology

Mechanisms of cilium-generated signaling (342)

A postdoctoral research position is open in the laboratory of William J. Snell, Ph.D., in the Department of Cell Biology at UT Southwestern Medical Center to study cellular and molecular mechanisms of cilium-generated signaling using the green alga Chlamydomonas as a model system. The primary cilium is well established as a key sensory and signaling organelle that is essential for development and homeostasis. Disruption of ciliary structure/function in humans leads to multiple disorders collectively termed the ciliopathies. Attesting to the ancient function of the organelle in sensory transduction, Chlamydomonas uses its two flagella/cilia for signaling during sexual reproduction.

Chlamydomonas offers several advantages as a system for studying cilium-generated signaling and regulation of the protein composition of the ciliary membrane. In addition to being able to use genetic, molecular biological, and ultrastructural approaches, it is particularly simple to isolate cilia from Chlamydomonas in quantities sufficient for biochemical studies. We have several ongoing projects, but the project a candidate works on will be arrived at based on specific interests and background. Applicants must have a Ph.D. and research training appropriate for our system. To apply, please email a copy of your resume, contact information for at least 3 referees, and a cover letter outlining your research interests. Visit the Snell Lab to learn more about our research.

William J. Snell, Ph.D.
Department of Cell Biology
University of Texas Southwestern Medical Center
6000 Harry Hines Blvd.
Dallas, TX 75390-9039
Phone: 214-648-3966
william.snell@utsouthwestern.edu

Primary Cilia and Cellular Signaling Pathways (#311)

The focus of the current research in our laboratory is to understand mechanisms of cellular signaling at the level of the primary cilia, and its relevance to human health and disease. The first cellular organelle to be described in biology, the primary cilium was long mistaken as a vestigial appendage. The primary cilia are now considered as vital sensory organelles for detection and transmission of a broad range of chemical and mechanical signals in most cells. Signaling mediated by the primary cilia plays fundamental roles in cellular differentiation, polarity, and cell cycle control. We utilize a variety of biochemical, cell biological, and reverse genetic approaches to understanding signaling mediated by cilia, and dissecting their role during cell cycle control and carcinogenesis. A detailed description of current lab projects can be found at the Mukhopadhyay Lab

One postdoctoral position is available in our laboratory to study multiple aspects of ciliary signaling. Candidates must have a recent Ph.D. or M.D./Ph.D., with less than three years of prior postdoctoral experience, and a demonstrated research record with at least one first author publication. Preference will be given to applicants with a strong background in cell and molecular biology, protein biochemistry, or mouse genetics. Please email saikat.mukhopadhyay@utsouthwestern.edu a copy of your current curriculum vitae, contact information for references, and a cover letter highlighting your prospective research plan.

Children's Research Institute at UT Southwestern

Functional Cancer Epigenomics (355)

A postdoctoral position is available in the laboratory of Jian Xu, Ph.D., in the Children’s Research Institute at UT Southwestern Medical Center to study the functional genomics of stem cells and cancer. Our laboratory focuses on the intersection of transcriptional control with stem cell biology, hematopoiesis and cancer. We employ epigenetics, functional genomics, genome editing, biochemistry, and mouse genetics to define epigenetic and genetic programs that control blood stem cell development, and how these processes go awry in cancer progression. The Xu lab at UTSW brings together enthusiastic scientists with diverse backgrounds, and provides a wide range of perspectives in a multi-disciplinary and collaborative team setting.

The successful candidate must hold a Ph.D. and/or M.D. degree with a strong background in molecular biology, genetics, biochemistry, or a related field. The ideal candidate will exhibit independence, flexibility, and creativity with a record of scientific productivity. Previous experience in epigenetics, cancer genomics, bioinformatics, and/or mouse models is strongly preferred.

To apply: please submit CV, a short summary of research interest and experience, and a list of three references to:

Jian Xu, Ph.D.
UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75390-8502
jian.xu@utsouthwestern.edu
Children's Research Institute at UT Southwestern

Dermatology, Department of

Molecular Mechanisms Regulating Tumorigenesis (314)

A postdoctoral research scholar position is immediately available in the laboratory of Lu Q. Le, M.D., Ph.D., in the Department of Dermatology and Simmons Comprehensive Cancer Center at UT Southwestern Medical Center.

This postdoctoral position is for highly motivated individuals interested in Cancer Biology and Stem Cell Biology to investigate early, initiating genetic and mircroenvironmental events that regulate tumorigenesis. Our research focuses on the identification of the cell origin and on elucidating the roles of microenvironment in tumor development.

We dissect the cellular and molecular mechanisms of carcinogensis from a developmental perspective using Neurofibromatosis Type 1 (NF1), a common tumor predisposition human genetic disorder, as a model. The laboratory is a collaborative effort between the Department of Dermatology and the Cancer Center, offering an extraordinarily rich environment that encompasses both basic and translational research. Candidates must hold a Ph.D., M.D./Ph.D., or M.D. degree and should possess good communication skills.
Interested candidates should send an updated CV, with names and contact information for three professional references, to:

Lu Q. Le, M.D., Ph.D.
Department of Dermatology
Simmons Comprehensive Cancer Center
UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75390-9069
lu.le@utsouthwestern.edu

Developmental Biology

Bioinformatics, Genomics, and Personalized Medicine in Kidney Cancer (337)

A postdoctoral position is available for a highly-motivated scholar to work in the area of genomics and personalized medicine in kidney cancer. The project is focused on integrating high-throughput data from next-generation sequencing, gene expression, and other genetic and epigenetic analyses using clinical samples and pre-clinical models. The successful candidate will have the opportunity to be part of a team made up of researchers, physicians and clinical geneticists that cares for patients with kidney cancer and will be involved in the evaluation of personalized patient cancer genomes. The ultimate goal is to leverage understanding of the molecular genetics and biology of kidney cancer to improve patient treatments. For more information about the research program, please see the Brugarolas Lab website

Candidates must have a Ph.D. in statistical genetics, bioinformatics, computer science, or a related field. The candidate should also have programming experience using Python, Perl, Java, or C/C++ and be familiar with tools such as R/Bioconductor or Matlab. A track record of productivity is essential. Successful applicants will have the opportunity to work in a translational research program spanning from molecular genetics to the clinic. 

Interested candidates should send a CV, statement of research interests and the names of three references to:
James Brugarolas, M.D., Ph.D.
5323 Harry Hines Blvd.
Dallas, TX 75390-9133
james.brugarolas@utsouthwestern.edu

Molecular Mechanisms and Translational Research in Kidney Cancer (336)

A postdoctoral research scholar position is available in the Brugarolas Lab for a highly-motivated scholar to study signaling mechanisms in renal cancer. 

Candidates must hold a Ph.D. degree and have a track record of productivity with publications in well-established journals. Successful applicants will have the opportunity to work in a translational research program spanning from the molecular genetics to the clinic.

Interested candidates should send a CV, statement of research interests and the names of three references to:
James Brugarolas, M.D., Ph.D.
5323 Harry Hines Blvd.
Dallas, TX 75390-9133
james.brugarolas@utsouthwestern.edu

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Hematology Oncology, Internal Medicine

Molecular Mechanisms Regulating Tumor Maintenance (358)

The Division of Hematology/Oncology and Simmons Cancer Center of UT Southwestern Medical Center are seeking two postdoctoral positions in the laboratory of Pier Paolo Scaglioni, M.D.

Areas of interest include:

  1. Cancer Metabolism: Characterization of the role of mutant KRAS in reprogramming lipid biogenesis in lung cancer.
  2. Cancer maintenance: Identification of the mechanisms that mediate the maintenance of mutant KRAS lung cancer. 
  3. Regulation of oncogenic networks: Study of the role of the SUMO E3 ligase PIAS1 in the regulation of PML nuclear bodies and c-MYC.

These research topics will be addressed with a combination of molecular/cellular biology techniques and mouse cancer models.

Position Requirements: Candidates must hold an M.D. and/or a Ph.D. degree. Experience in the field of cellular/cancer biology leading to publication in peer-reviewed journals is recommended.

Interested individuals should send the following information:

  1. A statement of interest explaining why the candidate is interested in the position and how the position might further the candidate’s career goals. 
  2. An updated CV.
  3. Names and contact information of three references.

Pier Paolo Scaglioni, M.D.
Assistant Professor
UT Southwestern Medical Center
5323 Harry Hines Blvd. 
Dallas, TX 75390-8852
pier.scaglioni@utsouthwestern.edu
Scaglioni Lab

Immunology, Department of

Pathogenic Mechanisms of M.Tuberculosis (329)

A postdoctoral position is available in the laboratory of Nicolai van Oers, Ph.D., in the Department of Immunology of UT Southwestern Medical center to study the pathogenic mechanisms of M. tuberculosis. Using RNA sequencing strategies, we have discovered a population of M. tuberculosis-encoded small RNAs (18-30 nucleotides) that are released in infected human macrophages. Several of these RNAs were also identified in the lung lesions of monkeys with latent tuberculosis infection.

Candidates must hold a Ph.D. and/or M.D. degree. We are seeking a postdoctoral researcher with molecular biology and/or biochemistry experience to identify and characterize a novel small RNA/microRNA-like processing system in mycobacteria. These studies are part of a collaborative effort with Tawanda Gumbo, M.D., with funding provided by the Gates Foundation. Interested individuals should send a CV, statement of interest, and a list of three references to:

Nicolai van Oers, Ph.D.
UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75390-9093
nicolai.vanoers@utsouthwestern.edu
van Oers Lab

Infectious Diseases, Internal Medicine

Innate immunity and Autoimmune Diseases (352)

A postdoctoral position is available in the lab of Nan Yan, Ph.D., in the Department of Internal Medicine to study innate immunity and autoimmune diseases. Candidates must have a Ph.D. and/or M.D. degree. Candidates should also have strong molecular biology, microbiology, or immunology background with extensive mouse experience. Candidates should be highly motivated and have recent publications from previous work.

Please send curriculum vitae and three letters of reference by email to:

Nan Yan, Ph.D.
Department of Internal Medicine
Division of Infectious Diseases
University of Texas Southwestern Medical Center
nan.yan@utsouthwestern.edu
Nan Yan Lab

Microbiology, Department of

Bacterial gene regulation and Lyme disease pathogenesis (341)

A postdoctoral position is available in the laboratory of Michael Norgard, Ph.D., in the Microbiology Department to study virulence gene regulation in Borrelia burgdorferi, the Lyme disease spirochete. Studies will focus on the RpoN (Sigma54)-RpoS alternative sigma factor regulatory cascade and, in particular, the role of BosR as an accessory molecule for pathway activation (see Z. Ouyang et al. 2010. BosR [BB0647] controls the RpoN-RpoS regulatory pathway and virulence expression in Borrelia burgdorferi by a novel DNA-binding mechanism. PLoS Pathogens 7: e1001272). The position offers the opportunity to conduct research in an attractive, dynamic research environment with outstanding resources. Candidates must have a Ph.D. with a background in bacterial genetics, gene regulation, bacterial pathogenesis, and molecular biology. Experience in spirochetology, animal models, and/or tick biology is preferred. Please send a C.V. and three letters of recommendation to:

Michael V. Norgard, Ph.D.
Chair, Department of Microbiology
UT Southwestern Medical Center
6000 Harry Hines Blvd.
Dallas, TX 75390-9048
michael.norgard@utsouthwestern.edu

Obstetrics and Gynecology, Department of

Biochemical and Biophysical investigation of RNA-mediated Gene Regulation (339)

The research group of Yunsun Nam, Ph.D., at UT Southwestern Medical Center is seeking a postdoctoral scholar. Our laboratory is housed in newly renovated space at the heart of the Cecil H. and Ida Green Center for Reproductive Biology Sciences, Department of Obstetrics and Gynecology at UT Southwestern Medical Center.

The overarching goal of our group is to elucidate the mechanistic details of RNA-regulated gene expression, by investigating the structure-function relationship of various protein/nucleic acid complexes. We are particularly interested in the gene regulation pathways relevant to mammalian development and cancer. Postdoctoral scholars will have many opportunities to learn the newest methods in biochemistry and biophysics, in addition to working in an exciting, fast-evolving area in the field of biological and biomedical sciences. We use various approaches, including X-ray crystallography, NMR spectroscopy, molecular biology, nucleic acid and protein biochemistry, high throughput sequencing, and eukaryotic cell-based studies. For more information, please refer to the Yunsun Nam Lab website.

Candidates must have a Ph.D. degree and a strong background in biochemistry (protein or nucleic acid) and/or structural biology. Interested individuals should submit a CV as a single pdf file, including contact information for 3 references, by email to: yunsun.nam@utsouthwestern.edu.

Hematophietic Stem Cells (338)

A postdoctoral position is available in the Bai Laboratory in the Green Center for Reproductive Biology of UT Southwestern Medical Center to study hematopoiesis development. Our laboratory has several exciting projects related to study transcriptional mechanisms that regulate the differentiation of hematopoietic stem cells (HSC). The potential project for this position will focus on identification of novel chromatin factors regulating HSC cell fate determination during normal and malignant hematopoiesis using a combination of genetic, biochemical, and genomic approaches.

Candidates must hold a Ph.D. and/or M.D. degree. Experience in genetics, molecular biology, or developmental biology leading to publication in peer-reviewed journals is recommended.

Interested individuals should send a CV, statement of interests, and a list of three references to:

Xiaoying Bai, Ph.D.
UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75390-8511
xiaoying.bai@utsouthwestern.edu
New faculty at the Green Center

Ophthalmology, Department of 

Genetics of Eye Disease (343)

A postdoctoral research opportunity in eye genetics is now available in the laboratory of V. Vinod Mootha, M.D., in the Department of Ophthalmology and the McDermott Center for Human Genetics at UT Southwestern Medical Center. Our NIH funded lab aims to identify novel genes underlying Fuchs’ endothelial corneal dystrophy and other anterior segment eye disorders. We are seeking a highly motivated fellow with a strong, proven publication record for a special opportunity to combine the new tools of genomics with functional studies. The candidate must hold a Ph.D. and/or M.D. degree and ideally have strong molecular and cellular biology skills. Qualified applicants should send a CV, a brief statement of research interests and goals, and contact information for three references to:
vinod.mootha@utsouthwestern.edu

V. Vinod Mootha, M.D.
UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75390-9057
Mootha Lab 

Cellular Mechanisms of Ocular Disease (331)

A postdoctoral position is currently available in the laboratory of John Hulleman, Ph.D., in the Department of Ophthalmology at the University of Texas Southwestern Medical Center. The Hulleman Laboratory is committed to understanding the underlying causes of inherited and idiopathic retinal disorders and developing novel therapies for them.

The successful candidate who will fill this position will apply chemical biology, functional genomics, and high-throughput screening approaches to understand the role of extracellular matrix proteins and stress-responsive signaling in the causation of retinal diseases. The candidate must be highly motivated and hardworking. The ideal candidate would be proficient in conventional molecular biology and biochemistry skills, protein analysis, as well as cell culture techniques.
Candidates must have a Ph.D. and/or M.D. degree, less than three years of postdoctoral experience and a strong publication record.

Interested applicants should send a brief statement of research interests as well as their C.V. and contact information for 3 references as a single PDF to:
John Hulleman, Ph.D.
UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75390-9057
john.hulleman@utsouthwestern.edu

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Pathology, Department of

Bioinformatics at UT Southwestern (357)

The Pathology Department is recruiting for a postdoctoral candidate. The focus is on the Analysis of Complex Datasets including: DNA-sequencing, RNA-sequencing, Metabolomics, and Drug Sensitivity Data. Specific emphasis will be placed on delineating the impact of specific pathways on disease progression and therapeutic response using data from clinically annotated tissue specimens and patient-derived models.

Ideal candidates should have experience with bioinformatics, a track record of leading projects to publication, and be creative in using computational methods to interrogate complex biological problems.
Postdoctoral fellows will be expected to direct independent projects in a multi-disciplinary setting, assist in mentoring junior lab members, and apply for independent fellowship funding. A long-term goal of the project is to bring the research to clinical application and fellows will have the opportunity to directly contribute to clinical trial development and interactions with the multi-disciplinary teams in molecular oncology.

Requirements:
1. PhD in a related discipline
2. Record of research accomplishment
3. Self-motivated with a positive attitude
4. Strong interpersonal skills

Interested individuals should send a CV, statement of interests, and a list of three references to:
Erik Knudsen, Ph.D.
UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75390-9072
erik.knudsen@utsouthwestern.edu
Attention:
linda.jones@utsuothwestern.edu

Neuronal Cell Death Research (353)

The Pathology Department at UT Southwestern Medical Center is recruiting for two postdoctoral positions to be filled January 2015 in the laboratory of Yingfei Wang, Ph.D., to study neuronal cell death after acute brain injury. We will use a combination of tools, including epigenomics, bioinformatics, proteomics, and mouse genetics, to study the molecular mechanism of PARP-1-dependent cell death (parthanatos) by focusing on the newly identified parthanatos-dependent AIF-associated nuclease (PAAN1) in acute brain injury. The project is supported by NIH grant. UTSW offers an excellent working environment and competitive benefits package.

Requirements: Candidates must have a Ph.D. or M.D./Ph.D. degree in biological sciences or other related disciplines. A strong background in molecular biology, biochemistry and animal models of global or focal ischemic stroke is desired. 

Interested individuals should send a cover letter with a brief description of research experience and interests, CV, and three supporting letters to: Yingfei Wang, Ph.D., yingfei.wang@utsouthwestern.edu.

Gene Regulation and Cancer Biology (354)

The Pathology Department at UT Southwestern Medical Center is recruiting for several postdoctoral positions expected to be filled in January 2015, in the laboratory of Weibo Luo, Ph.D., to study gene regulation by hypoxia-inducible factors in breast cancer (Cell 2011, 145(5):732-44; PNAS 2012, 109(49):E3367-76). We are particularly interested in understanding the crosstalk of oxygen homeostasis, epigenetics, and metabolism in breast cancer progression. The cutting-edge techniques including proteomics, next generation sequencing, and metabolomics are used in our studies. Our research is supported by NCI and CPRIT.

Requirements: We are seeking highly motivated candidates with a Ph.D. or M.D./Ph.D. Interested candidates must have 1) a strong background in biochemistry, molecular biology, and oncology, 2) a strong publication record, and 3) good communication skills. Experience with bioinformatics is a plus.

Interested individuals should send a cover letter, CV, and three reference letters via email to Weibo Luo, Ph.D., at weibo.luo@utsouthwestern.edu.

Pharmacology, Department of 

Glycosylation Pathways of the ER (346)

A postdoctoral position is available in the laboratory of Mark Lehrman, Ph.D., in the Department of Pharmacology UT Southwestern Medical Center to study glycosylation pathways of the endoplasmic reticulum, with emphasis on dysregulation of glycoprotein synthesis by human disease and viral infection. Additional information can be found at the Lehrman Lab

Candidates must hold a Ph.D. or comparable degree, experience in biochemistry or glycobiology. Interested individuals should send a CV, statement of interests, and a list of three references to:

Mark Lehrman, Ph.D.
Professor, Department of Pharmacology
UT Southwestern Medical Center
5323 Harry Hines Blvd
Dallas, TX 75390-9041
mark.lehrman@utsouthwestern.edu

Sugar Biosynthesis and ER Stress (345)

A postdoctoral position is available in the laboratory of Mark Lehrman, Ph.D., in the Department of Pharmacology UT Southwestern Medical Center to study regulation of sugar biosynthesis by endoplasmic reticulum stress, with application to viral infection. Additional information can be found at the Lehrman Lab

Candidates must hold a Ph.D. or comparable degree, experience in biochemistry. Interested individuals should send a CV, statement of interests, and a list of three references to:

Mark Lehrman, Ph.D.
Professor, Department of Pharmacology
UT Southwestern Medical Center
5323 Harry Hines Blvd 
Dallas, TX 75390-9041
mark.lehrman@utsouthwestern.edu

Mechanism of G Protein Signal Control (330)

A postdoctoral researcher position is open in the laboratory of Elliot Ross, Ph.D., in the Department of Pharmacology at UT Southwestern Medical Center to study molecular mechanisms of signal amplification, integration, and timing in receptor-G protein-effector systems. We are particularly interested in how receptors and G protein GAPs independently and cooperatively regulate signal amplitude and kinetics, and how multiple G protein inputs regulate effector proteins additively or synergistically. Multiple quantitative approaches and model systems are applicable to this research, both in cells and in reconstituted systems of purified proteins.

Specific projects will be determined by the person’s interests, talents and experience. I welcome suggestions for new projects or strategies. Our group tries to focus on essential mechanisms of molecular signaling and quantitative experimental approaches. Our group is in the Department of Pharmacology and Green Center for Systems Biology, and affiliated with the Cell Regulation and Molecular Biophysics Graduate Programs. You can learn more about our work at the Ross Lab website.

These projects, or their spin-offs, will attract people with diverse backgrounds. Strong applicants could come from a signaling background, or from other areas of biochemistry, biophysics, or systems biology. Applicants must hold a Ph.D. degree and demonstrate research experience appropriate to the project. Applications must include a CV, contact information for referees and a statement of research interests.

Elliott M. Ross, Ph.D.
Professor, Department of Pharmacology
Green Center for Systems Biology
University of Texas Southwestern Medical Center
6001 Forest Park Road
Dallas, TX 75230-9041
ross@utsw.swmed.edu

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Psychiatry, Department of

Molecular Biologist \ Biochemist (356)

Fellow-Research Associate position is available immediately in the lab of Saïd Kourrich at UT Southwestern Medical Center. The applicant will join a highly collaborative research group that focuses on the relationships between drug-induced changes in synaptic/intrinsic excitability and the development of drug addiction. The successful applicant will investigate signaling pathways that contribute to drug-induced changes in specific voltage-gated ion channels. Experiments will involve a combination of in vitro (cell culture) and brain slice electrophysiology.

The successful candidate must hold a Ph.D. in cell biology, neurobiology, biology, or closely related field. Strong expertise in cell culture (primary neuronal or neuroblastoma lines) and immunocytochemistry are required. Experience in DNA constructs, cell transfection, and ligand-receptor binding assay would be appreciated. Experience in electrophysiological patch-clamp recordings is not required. To apply, send CV and names of three references directly to: said.kourrich@utsouthwestern.edu.

Said Kourrich, Ph.D.
Assistant Professor
UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75390-9070
Department: Psychiatry
Kourrich Lab 

Radiology, Department of

Chemistry for Molecular Imaging (344)

The UT Southwestern Medical Center has recently established the Cyclotron and Radiochemistry Program, which encompasses a GE PETTrace cyclotron, three small animal scanners (a Siemens Inveon PET/CT Multimodality System, a Bioscan NanoSPECT/CT Plus system, and an ASPECT M2 1T MRI system), and state-of-the-art chemistry and radiochemistry laboratories and quality assurance facilities equipped with high-end analytical instruments including ICP/MS, Q-TOF LC/MS, FPLC, and HPLC. With research focus on design, synthesis, and biological evaluations of targeted imaging probes for noninvasive disease detection and therapy assessment, the Program is poised to stand at the forefront of molecular imaging.

The Program has an immediate opening for a postdoctoral researcher for design and synthesis of molecular imaging probes. Candidates with Ph.D. in synthetic or medicinal chemistry and career interests in molecular imaging are encouraged to apply. Hands-on experience with small animal imaging, medical radioisotopes, and live animals is desirable but not required. Interested individuals should send current curriculum vitae and contact information for three references to:

Hancheng Cai, Ph.D.
Assistant Professor 
Department of Radiology and Advanced Imaging Research Center
Chief Radiochemist, Cyclotron and Radiochemistry Program
UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75390-8542
hancheng.cai@utsouthwestern.edu

There are no positions available in your field of choice. We update ads on a regular basis so please check back soon. 

UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. In accordance with federal and state law, the University prohibits unlawful discrimination, including harassment, on the basis of: race; color; religion; national origin; gender, including sexual harassment; age; disability; citizenship; and veteran status. In addition, it is UT Southwestern policy to prohibit discrimination on the basis of sexual orientation, gender identity, or gender expression.

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