Division faculty are engaged in a broad spectrum of research activities across the clinical and translational research spectrum including: clinical epidemiology, outcomes, health services, quality improvement, medical errors, patient safety, disparities, geriatrics, palliative care, medical education, HIV, chronic disease, and translational research studies.

The Parkland-UT Southwestern Center for Clinical Innovation focuses on evidence-based approaches to improving the quality and efficiency of care in the Parkland Memorial Health System with an emphasis on harnessing/leveraging medical information technologies.

Key research faculty include:
Ethan A. Halm, M.D., M.P.H.
Ruben Amarasingham, M.D., M.B.A.
Linda Cavillo-King, M.D., M.P.H.
Rody Cox, M.D.
Kathryn Eubank, M.D.
Elizabeth Paulk, M.D.
Dolores Peterson, M.D., Ph.D.
Colleen Sam, M.D., M.P.H.