Human Cancer Cell Lines

John Minna, M.D., and Adi Gazdar, M.D., both of UT Southwestern Medical Center, have spent decades at the forefront of biomedical research on lung cancer, breast cancer, and other cancer sites. Thanks to their commitment to careful curation, the HCC cell line collection meets the urgent research need for a well-characterized, broad, and diverse collection of human cancer cell lines.

Research has confirmed that these cell lines retain the molecular characteristics of primary tumors even after lengthy culture periods, making them suitable model systems for biomedical studies of primary neoplasms.

The HCC collection includes rare or unique cell lines and cancers from a diversity of ages and ethnicities. To review journal articles describing these cell lines and confirming their value as tumor models, please see these two articles:

Lung Cancer 68 (2010) 309-318
J Natl Cancer Inst 2010;102:1310-1321

For information on non-exclusive licensing terms for one or more of these cell lines, please contact the Office for Technology Development at 214-648-1888 or

UT Southwestern Human Cancer Cell Lines

Cell Line NumberOther name (ATCC)Tumor TypeSubtypeAgeRaceGender
HCC0010 Colorectal Adenocarcinoma 60 Black M
HCC0012 Kidney Renal Cell Carcinoma 45 Unknown F
HCC0015 Lung Squamous 55 Black M
HCC0019 Unknown Primary Metastatic Adenocarcinoma 58 Caucasian F
HCC0031 Lung Squamous 57 Caucasian M
HCC0033 Lung SCLC 53 Caucasian M
HCC0038 CRL-2314 Breast Ductal Carcinoma 50 Caucasian F
HCC0041 Lung SCLC 67 Unknown F
HCC0044 Lung Adenocarcinoma 54 Caucasian F
HCC0060 Ovary Cystoadenocarcinoma 26 Black F
HCC0070 CRL-2315 Breast Ductal Carcinoma 50 Black F
HCC0078 Lung Adenocarcinoma 55 Caucasian M
HCC0089 Kidney Renal Cell Carcinoma 64 Caucasian F
HCC0090 Bladder Transitional Cell Carcinoma 47 Caucasian M
HCC0095 Lung Squamous 65 Caucasian M
HCC0103 Lung Adenocarcinoma 54 Caucasian F
HCC0122 Lung Adenocarcinoma 48 Black M
HCC0128 Kidney Renal Cell Carcinoma 75 Caucasian F
HCC0149 Lung Adenocarcinoma 58 Black F
HCC0193 Lung Adenocarcinoma 71 Caucasian F
HCC0202 CRL-2316 Breast Ductal Carcinoma 82 F
HCC0229 Cervix Squamous Cell Carcinoma 35 Black F
HCC0242 Bladder Transitional Cell Carcinoma 62 Unknown M
HCC0267 Breast Ductal Carcinoma 57 Hispanic F
HCC0317 Kidney Transitional Cell Carcinoma, Shaffer's Syndrome 49 M
HCC0345 Larynx Squamous Cell Carcinoma 60 Black M
HCC0364 Lung Adenocarcinoma 76 M
HCC0366 Lung Adenosquamous 80 Unknown F
HCC0374 Spleen Adenocarcinoma 55 Black F
HCC0379 Breast Ductal Carcinoma 70 Black F
HCC0407 Brain Glioblastoma 48 Unknown M
HCC0420 Breast Neuroendocrine Carcinoma 62 Unknown F
HCC0435 Lung Squamous 63 Caucasian M
HCC0446 Lung Adenocarcinoma 49 Unknown F
HCC0461 Lung Adenocarcinoma 69 Caucasian M
HCC0515 Lung Adenocarcinoma 39 Caucasian F
HCC0590 Merkel Cell Carcinoma of Back and Shoulder 60 Unknown F
HCC0597 Uterus Endometrial Carcinoma 64 Caucasian F
HCC0630 Ovary Carcinoma 32 Hispanic F
HCC0653 Adrenal Gland Adrenal Carcinoma 67 Caucasian M
HCC0711 Colorectal Adenocarcinoma 59 Black M
HCC0712 Breast Ductal Carcinoma 53 Asian F
HCC0815 Lung Adenocarcinoma Hispanic M
HCC0824 Lung Adenocarcinoma 59 Caucasian F
HCC0826 Colorectal Carcinoma 40 Black F
HCC0827 CRL-2868 Lung Adenocarcinoma (BAC features) 38 Caucasian F
HCC0845 Lung Mesothelioma 37 Caucasian F
HCC0850 Ovary Small Cell Carcinoma 60 Black F
HCC0853 T-cell Leukemia Prolymphocytic Leukemia 48 Caucasian M
HCC0880 Kidney Renal Cell Carcinoma 58 Hispanic F
HCC0889 Thyroid Papillary Thyroid Carcinoma 47 Black M
HCC0954 Lung Large Cell, Neuroendocrine, and SC 41 Caucasian F
HCC0970 Lung SCLC 62 Unknown M
HCC0973 Lung Merkel Cell Carcinoma 56 Black M
HCC0985 Colorectal Adenocarcinoma 45 Unknown M
HCC1007 Breast Ductal Carcinoma 67 Black F
HCC1008 CRL-2320 Breast Ductal Carcinoma 67 Black F
HCC1010 Kidney Sarcomatoid Renal Cell Carcinoma 61 Hispanic M
HCC1011 Kidney Cystic Renal Cell Carcinoma 37 Hispanic M
HCC1033 Colorectal Adenocarcinoma 54 Unknown M
HCC1042 Ovary Papillary Serous Carcinoma 42 Caucasian F
HCC1054 Kidney Renal Cell Carcinoma 56 Caucasian F
HCC1057 Bladder Transitional Cell Carcinoma 43 Caucasian M
HCC1068 Pharynx Squamous Cell Carcinoma 48 Black M
HCC1106 Uterus Papillary Clear Cell Carcinoma 61 Black F
HCC1143 CRL-2321 Breast Ductal Carcinoma 50 Caucasian F
HCC1159 Ovary Carcinoma 48 Unknown F
HCC1162 Uterus Adenocarcinoma 58 Black F
HCC1171 Lung NSCLC (poorly differentiated) 58 Caucasian M
HCC1187 CRL-2322 Breast Ductal Carcinoma 41 Caucasian F
HCC1192 Lung Adenocarcinoma 68 Caucasian M
HCC1195 Lung Adenocarcinoma (mixed) 47 Black M
HCC1205 Kidney Transitional Cell Carcinoma 61 Caucasian F
HCC1210 Lung Adenocarcinoma 62 Unknown M
HCC1217 Kidney Renal Cell Carcinoma 50 Caucasian M
HCC1261 Lung Adenocarcinoma
HCC1263 Colorectal Adenocarcinoma 20 Black F
HCC1266 Lung SCLC 52 Caucasian F
HCC1311 Breast Ductal Carcinoma 38 Black F
HCC1313 Lung Squamous 51 M
HCC1314 Bladder Transitional Cell Carcinoma 45 M
HCC1319 Kidney Renal Cell Carcinoma 68 Caucasian M
HCC1323 Breast Ductal Carcinoma 73 Black F
HCC1347 Kidney Renal Cell Carcinoma 66 Caucasian F
HCC1354 Uterus Endometrial Carcinoma 75 Unknown F
HCC1359 Lung Large Cell 55 Black F
HCC1360 Bladder Adenocarcinoma 52 Caucasian M
HCC1367 Colorectal Adenocarcinoma
HCC1375 Bowel Small Bowel Tumor 57 Caucasian M
HCC1385 Under investigation 55 Black F
HCC1386 Under investigation 77 Caucasian F
HCC1395 CRL-2324 Breast Ductal Carcinoma 40 Caucasian F
HCC1419 CRL-2326 Breast Ductal Carcinoma 42 Hispanic F
HCC1426 Ovary Papillary Serous Adenocarcinoma 37 Unknown F
HCC1428 CRL-2327 Breast Adenocarcinoma 49 Caucasian F
HCC1438 Lung Large Cell 43 Black M
HCC1445 Lung Carcinoma 68 M
HCC1448 Bone Adenocarcinoma 49 Black F
HCC1482 Uterus Adenocarcinoma 62 Caucasian F
HCC1493 Breast Adenocarcinoma 43 M
HCC1498 Melanoma Melanoma 37 Caucasian M
HCC1500 CRL-2329 Breast Ductal Carcinoma 32 Black F
HCC1501 Lung Adenocarcinoma
HCC1534 Lung Adenocarcinoma
HCC1561 Lung Adenocarcinoma 72 M
HCC1569 CRL-2330 Breast Metaplastic Carcinoma 70 Black F
HCC1576 Adrenal Gland Under investigation
HCC1581 Lung Adenocarcinoma 61 Caucasian F
HCC1588 Lung Squamous 63 Black F
HCC1599 CRL-2331 Breast Ductal Carcinoma 45 Caucasian F
HCC1623 Colorectal Adenocarcinoma 58 Black F
HCC1629 Lung SCLC 64 Caucasian M
HCC1671 Lung Adenocarcinoma 81 Caucasian M
HCC1685 Breast Ductal Carcinoma 28 Hispanic F
HCC1686 Lung Adenocarcinoma 50 Caucasian F
HCC1688 Uterus Leiomyosarcoma 60 Black F
HCC1705 Lung Adenocarcinoma
HCC1719 Lung Adenocarcinoma 60 Black M
HCC1739 Breast Ductal Carcinoma (in-situ) 51 Caucasian F
HCC1772 Lung Adenocarcinoma 35 Caucasian F
HCC1806 CRL-2335 Breast Acantholytic Squamous Cell 60 Black F
HCC1820 Lung Adenocarcinoma
HCC1833 Lung Adenocarcinoma 69 Caucasian F
HCC1897 Lung Squamous 47 Black M
HCC1908 Lung Adenocarcinoma (poorly differentiated) 58 Caucasian F
HCC1937 CRL-2336 Breast Ductal Carcinoma 23 Caucasian F
HCC1943 Ureter Transitional Cell Carcinoma 63 Unknown M
HCC1944 Lung Adenocarcinoma M
HCC1945 Lung Adenocarcinoma 70 F
HCC1954 CRL-2338 Breast Ductal Carcinoma 61 Indian F
HCC1963 Lung Adenocarcinoma 66 Caucasian M
HCC1972 Uterus Endometrial Adenocarcinoma 54 Caucasian F
HCC1974 Lung Adenocarcinoma
HCC2041 Breast Medullary Carcinoma
HCC2108 Lung Adenocarcinoma
HCC2157 CRL-2340 Breast Ductal Carcinoma 48 Black F
HCC2185 Breast Metastatic Lobular Carcinoma F
HCC2270 Lung Adenocarcinoma 64 Caucasian F
HCC2279 Lung Adenocarcinoma 52 Asian F
HCC2302 Lung Adenocarcinoma
HCC2308 Ovary Endometrioid Adenocarcinoma 64 Caucasian F
HCC2312 Ovary Epithelial Malignant Neoplasm 16 Caucasian F
HCC2344 Lung Squamous 60 Black M
HCC2352 Lung Adenosquamous (mixed) 59 Black M
HCC2374 Lung Large Cell Neuroendocrine 69 Black F
HCC2389 Breast Adenocarcinoma 57 Unknown F
HCC2393 Lung SCLC
HCC2414 Breast Ductal Carcinoma 42 Hispanic F
HCC2433 Lung SCLC 57 Black M
HCC2450 Lung Squamous 52 Caucasian M
HCC2677 Lung Adenocarcinoma 55 Caucasian F
HCC2688 Breast Ductal Carcinoma F
HCC2713 Breast Ductal Carcinoma 35 Black F
HCC2771 Breast Ductal Carcinoma 40 F
HCC2783 Lung SCLC 67 Caucasian M
HCC2814 Lung Squamous 55 Caucasian M
HCC2846 Bladder Transitional Cell Carcinoma 71 F
HCC2885 Lung NSCLC
HCC2935 CRL-2869 Lung Adenocarcinoma 39 Caucasian M
HCC3051 Lung Large Cell 63 Black M
HCC3153 Breast Ductal Carcinoma F
HCC4006 CRL-2871 Lung Adenocarcinoma Caucasian M
HCC4011 Lung Adenocarcinoma 53 Caucasian M
HCC4017 Lung Large Cell 62 Caucasian F
HCC4018 Lung Adenocarcinoma 75 Caucasian F
HCC4019 Lung Adenocarcinoma 40 Caucasian M